Patents by Inventor Balaji SITHARAMAN
Balaji SITHARAMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230108396Abstract: The present invention provides for a process for synthesis of carbon beads comprising sub-micron size, micron size or milli size. The process enables modulation of the viscous slurry for synthesis of the carbon beads with improved physico-chemical properties. The process enhances ability of the carbon beads to withstand extreme pH and high temperatures. The present invention also provides a composition for synthesis of the carbon beads. The present invention also provides a microfluidic droplet generator for synthesizing the carbon beads. The carbon beads synthesized by the present invention are applicable in separation, filtration, purification, wires and cables, electrodes, sensor, composite and additive manufacturing, pharmaceutical delivery applications.Type: ApplicationFiled: March 2, 2021Publication date: April 6, 2023Inventors: Michael Parente, Balaji Sitharaman
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Patent number: 10610607Abstract: The present invention provides a magnetic graphene-like nanoparticle or graphitic nano- or microparticle. The magnetic graphene-like nanoparticle or graphitic nano- or microparticle of the invention exhibits a high relaxivity, and is useful as a MRI contrast agent. The present invention also provides a composition for use with MRI imaging, comprising a sufficient amount of the magnetic graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. The present invention also provides methods of using the magnetic graphene-like nanoparticles or graphitic nano- or microparticles as MRI contrast agents. The present invention further provides methods of producing the magnetic graphene-like nanoparticle or graphitic nano- or microparticle.Type: GrantFiled: July 7, 2017Date of Patent: April 7, 2020Assignee: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Bhavna S. Paratala
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Patent number: 10343918Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: GrantFiled: November 14, 2017Date of Patent: July 9, 2019Assignee: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Publication number: 20180147296Abstract: The present disclosure is directed to carbon nanomaterials and methods for delivering a drug to a mammal's cell including administering the carbon nanomaterial to the mammal. The present disclosure is also directed to carbon nanomaterials and methods for delivering a nucleic acid to a mammal's cell including administering the carbon nanomaterial to the mammal.Type: ApplicationFiled: May 26, 2016Publication date: May 31, 2018Applicant: The Research Foundation for The State University of New YorkInventors: Balaji SITHARAMAN, Sayan Mullick CHOWDHURY
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Publication number: 20180086640Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: ApplicationFiled: November 14, 2017Publication date: March 29, 2018Applicant: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Patent number: 9833522Abstract: The present invention provides a composition for use with photoacoustic or thermoacoustic imaging, comprising a sufficient amount of the graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. The present invention also provides methods of using the graphene-like nanoparticles or graphitic nano- or microparticles as PAT/TAT contrast agents.Type: GrantFiled: December 23, 2014Date of Patent: December 5, 2017Assignee: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Patent number: 9815696Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: GrantFiled: March 16, 2017Date of Patent: November 14, 2017Assignee: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Publication number: 20170312374Abstract: The present invention provides a magnetic graphene-like nanoparticle or graphitic nano- or microparticle. The magnetic graphene-like nanoparticle or graphitic nano- or microparticle of the invention exhibits a high relaxivity, and is useful as a MRI contrast agent. The present invention also provides a composition for use with MRI imaging, comprising a sufficient amount of the magnetic graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. The present invention also provides methods of using the magnetic graphene-like nanoparticles or graphitic nano- or microparticles as MRI contrast agents. The present invention further provides methods of producing the magnetic graphene-like nanoparticle or graphitic nano- or microparticle.Type: ApplicationFiled: July 7, 2017Publication date: November 2, 2017Applicant: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Bhavna S. Paratala
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Patent number: 9713650Abstract: A magnetic graphene-like nanoparticle or graphitic nano- or microparticle exhibits a high relaxivity, and is useful as a MRI contrast agent. A composition for use with MRI imaging, comprising a sufficient amount of the magnetic graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. Methods of using the magnetic graphene-like nanoparticles or graphitic nano- or microparticles as MRI contrast agents. Methods of producing the magnetic graphene-like nanoparticle or graphitic nano- or microparticle.Type: GrantFiled: May 7, 2012Date of Patent: July 25, 2017Assignee: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Bhavna S. Paratala
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Publication number: 20170190577Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: ApplicationFiled: March 16, 2017Publication date: July 6, 2017Applicant: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Patent number: 9630848Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: GrantFiled: April 4, 2013Date of Patent: April 25, 2017Assignee: The Research Foundation for The State of New YorkInventors: Balaji Sitharaman, Gaurav Lalwani
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Publication number: 20150217002Abstract: The method of the present disclosure is directed towards a method for determining the concentration of an analyte in a mammal's bloodstream. This method includes the following steps; applying a patch to the mammal's skin, the patch configured to transmit a reporter through the mammal's skin, wherein the reporter is configured to have an affinity for the analyte and is capable of exhibiting a detectable change in fluorescence upon binding to the analyte, subjecting a portion of the mammal's skin to Near Infrared Spectroscopy (NIRS), detecting fluorescence emission intensity and calculating the concentration of the analyte based on the detected fluorescence emission. The system of the present disclosure is directed towards an analyte monitoring system.Type: ApplicationFiled: August 9, 2013Publication date: August 6, 2015Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: Lilianne R. Mujica-Parodi, Balaji Sitharaman, Daniel Dedora, Sayan Mullick Chowdhury
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Publication number: 20150182642Abstract: The present invention provides a composition for use with photoacoustic or thermoacoustic imaging, comprising a sufficient amount of the graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. The present invention also provides methods of using the graphene-like nanoparticles or graphitic nano- or microparticles as PAT/TAT contrast agents.Type: ApplicationFiled: December 23, 2014Publication date: July 2, 2015Inventors: Balaji Sitharaman, Gaurav Lalwani
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Publication number: 20150118492Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.Type: ApplicationFiled: April 4, 2013Publication date: April 30, 2015Inventors: Balaji Sitharaman, Gaurav Lalwani
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Publication number: 20150080770Abstract: This invention relates to stimulation of stem cells and other progenitors of differentiated cells using nanoparticles and electromagnetic stimulation. The invention provides a method for differentiating mesenchymal stem cells (MSCs) towards osteoblasts and other connective tissue. The invention provides osteoinductive materials useful for bone regeneration and reconstruction in treatment of bone trauma and bone related diseases, and to correct birth defects. The invention also provides for reduced adipogenesis.Type: ApplicationFiled: November 26, 2014Publication date: March 19, 2015Inventors: Balaji SITHARAMAN, Jon LONGTIN
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Publication number: 20140303525Abstract: The present invention provides a method for non-invasive acoustic stimulation of stem cells and/or progenitor cells in a patient. The invention also provides a device for non-invasive stimulation of stem cells and/or progenitor cells in the patient by generating and delivering acoustic waves of a suitable frequency and intensity to the stem cells and/or progenitor cells. The method and device of the present invention is useful in enhancing regeneration of bones and other tissues, such as cartilages, muscles, and nerve tissues, in a patient, for treatment of conditions such as bone loss or fracture.Type: ApplicationFiled: June 8, 2012Publication date: October 9, 2014Inventor: Balaji Sitharaman
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Publication number: 20140161730Abstract: A magnetic graphene-like nanoparticle or graphitic nano- or microparticle exhibits a high relaxivity, and is useful as a MRI contrast agent. A composition for use with MRI imaging, comprising a sufficient amount of the magnetic graphene-like nanoparticles or graphitic nano- or microparticles and one or more physiologically acceptable carriers or excipients. Methods of using the magnetic graphene-like nanoparticles or graphitic nano- or microparticles as MRI contrast agents. Methods of producing the magnetic graphene-like nanoparticle or graphitic nano- or microparticle.Type: ApplicationFiled: May 7, 2012Publication date: June 12, 2014Applicant: The Research Foundation for The State University of New YorkInventors: Balaji Sitharaman, Bhavna S. Paratala
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Publication number: 20120141543Abstract: Novel methods and compositions of nanocomposites are provided. One exemplary composition comprises a biocompatible polymer, such as polypropylene fumarate, and a carbon nanotube, such as a single walled carbon nanotube, an ultra-short carbon nanotube, or a substituted ultra-short carbon nanotube. An exemplary method comprises providing a biocompatible polymer and a carbon nanotube and combining a biocompatible polymer and a carbon nanotube to form a nanocomposite. Another exemplary method comprises providing a nanocomposite comprising a biocompatible polymer and a carbon nanotube and administering the composition to a subject.Type: ApplicationFiled: January 11, 2008Publication date: June 7, 2012Inventors: Balaji Sitharaman, Antonios G. Mikos, Lon J. Wilson, Xinfeng Shi
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Publication number: 20120076830Abstract: A method for differentiating mesenchymal stem cells (MSCs) towards osteoblasts and other connective tissue using nanoparticles and electromagnetic stimulation Osteoinductive materials produced using said method may be useful for bone regeneration and reconstruction in treatment of bone trauma and bone related diseases, and to correct birth defects.Type: ApplicationFiled: December 1, 2009Publication date: March 29, 2012Inventors: Balaji Sitharaman, Longtin Jon
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Publication number: 20120052004Abstract: A contrast agent composition comprising at least one carbon nanotube and a metal catalyst. A method for obtaining a magnetic resonance image, the method comprising: administering to a subject a contrast agent composition, wherein a contrast agent composition comprises at least one carbon nanotube and a metal catalyst; and obtaining a magnetic resonance image of at least a portion of the subject in which the contrast agent is disposed.Type: ApplicationFiled: February 7, 2011Publication date: March 1, 2012Inventors: Lon J. Wilson, Jeyarama Subramanian Ananta Narayanan, Balaji Sitharaman, Keith Bennett Hartman