Patents by Inventor Balaji Srinivasan Santhanam

Balaji Srinivasan Santhanam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200394491
    Abstract: A system and method for providing sequencing of biomolecules, which can be used for differential analysis of a test sample from a normal sample.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 17, 2020
    Inventors: Yee Him Cheung, Nevenka Dimitrova, Balaji Srinivasan Santhanam
  • Publication number: 20190071718
    Abstract: A system for characterizing intercellular communication and heterogeneity in cancer tumors, and more particularly a method for detecting sub-populations and receptor-ligand states for providing predictive information in relation to cancer and cancer treatment is disclosed. The system comprises the steps of obtaining from a NGS sequencer, single-cell RNA-seq for a plurality of cells within a tumor, correlation with a plurality of data sets from a curated gene list of receptor-ligand pairs, normalizing their transcript abundance data, assigning states (e.g. 0,1,2,3) to each curated receptor-ligand pair in each cell (e.g.
    Type: Application
    Filed: April 7, 2017
    Publication date: March 7, 2019
    Inventors: Balaji Srinivasan Santhanam, Yee Him Cheung, Vartika Agrawal, Johanna Maria De Bont, Nevenka Dimitrova