Patents by Inventor Baohua M. Huang

Baohua M. Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional small molecules
    Patent number: 9402911
    Abstract: The present invention relates to dendrimer synthesis. Specifically, the present invention relates to dendrimer compositions (e.g., scaffolds) capable of copper-free click conjugation for use in the synthesis of functionalized dendrimers, and methods of use of the same.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: August 2, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James R. Baker, Jr., Baohua M. Huang, Thommey P. Thomas
  • Pro-drug complexes and related methods of use
    Patent number: 8853151
    Abstract: The present invention provides methods, compositions and applications for efficient, site-specific drug delivery using pro-drug complexes comprising one or more functional groups (e.g., imaging agents, targeting agents, and trigger agents) conjugated with a therapeutic agent (e.g., a chemotherapeutic agent), methods of synthesizing the same, as well as systems and methods utilizing the therapeutic and diagnostic compositions (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, etc.))). Trigger agents include an indolequinone; attachment groups include a triazole ring; and therapeutic agents include camptothecin.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: October 7, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Baohua M. Huang, Thommey P. Thomas
  • MULTIFUNCTIONAL SMALL MOLECULES
    Publication number: 20140294733
    Abstract: The present invention relates to dendrimer synthesis. Specifically, the present invention relates to dendrimer compositions (e.g., scaffolds) capable of copper-free click conjugation for use in the synthesis of functionalized dendrimers, and methods of use of the same.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 2, 2014
    Inventors: James R. Baker, JR., Baohua M. Huang, Thommey P. Thomas
  • PRO-DRUG COMPLEXES AND RELATED METHODS OF USE
    Publication number: 20120171227
    Abstract: The present invention provides methods, compositions and applications for efficient, site-specific drug delivery using pro-drug complexes comprising therapeutic agents and one or more functional groups (e.g., imaging agents, targeting agents, and trigger agents). In particular, the present invention relates to pro-drug complexes comprising one or more functional groups conjugated with a therapeutic agent (e.g., a chemotherapeutic agent), methods of synthesizing the same, as well as systems and methods utilizing the therapeutic and diagnostic compositions (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, etc.)).
    Type: Application
    Filed: June 30, 2010
    Publication date: July 5, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James R. Baker, JR., Baohua M. Huang, Thommey P. Thomas