Patents by Inventor Barry D. Sears

Barry D. Sears has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180206542
    Abstract: Specialized high-protein, reduced-carbohydrate edible food products with excellent organoleptic and stability characteristics can be produced which modulate or reduce insulin resistance and increase fat-free mass in a calorie-restricted dietary regimen. These specialized food products, ranging from breads, pasta, pizza dough, tortillas, bagels, pastries, and other similar food products higher in protein and lower in carbohydrate content, have a significant clinical benefit. Modulation or reduction of insulin resistance using such food products has been observed to be clinically relevant and can be used for the treatment of many chronic disease conditions associated with increased insulin resistance.
    Type: Application
    Filed: August 4, 2016
    Publication date: July 26, 2018
    Inventor: Barry D. Sears
  • Publication number: 20170014432
    Abstract: The invention relates to compositions and methods for reducing chronic low-level inflammation associated with chronic conditions. Specifically, the invention relates to compositions of hydrophobic derivatives of aspirin and/or hydrophobic derivatives of sesamol in combination with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and their methods for reducing chronic low-level inflammation associated with chronic conditions including obesity, metabolic syndrome, diabetes, cardiovascular disease, cancer, auto-immune disorders, ocular and neurological disorders in a mammal.
    Type: Application
    Filed: March 6, 2015
    Publication date: January 19, 2017
    Inventor: Barry D. SEARS
  • Publication number: 20150190368
    Abstract: The invention relates to a novel class of inhibitors of arachidonic acid formation that can be useful for treating inflammatory conditions. Specifically, the invention relates to derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Application
    Filed: February 12, 2015
    Publication date: July 9, 2015
    Inventor: Barry D. Sears
  • Patent number: 8987325
    Abstract: The invention relates to a novel class of inhibitors of arachidonic acid formation that can be useful for treating inflammatory conditions. Specifically, the invention relates to derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: March 24, 2015
    Inventor: Barry D. Sears
  • Publication number: 20140056988
    Abstract: The invention relates to a novel class of inhibitors of arachidonic acid formation that can be useful for treating inflammatory conditions. Specifically, the invention relates to derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Application
    Filed: May 14, 2013
    Publication date: February 27, 2014
    Inventor: Barry D. Sears
  • Publication number: 20120251624
    Abstract: The invention relates to a novel class of inhibitors of arachidonic acid formation that can be useful for treating inflammatory conditions. Specifically, the invention relates to derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Application
    Filed: December 9, 2011
    Publication date: October 4, 2012
    Inventor: Barry D. SEARS
  • Publication number: 20100068292
    Abstract: The invention relates to a novel class of inhibitors of arachidonic acid formation that can be useful for treating inflammatory conditions. Specifically, the invention relates to derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Application
    Filed: November 17, 2009
    Publication date: March 18, 2010
    Inventor: Barry D. Sears
  • Publication number: 20090012157
    Abstract: The invention relates to a novel class of inhibitor of arachidonic acid useful for treating inflammatory conditions. Specifically, the invention relates to hydrophobic and hydrophilic derivatives of sesamol that confer lower toxicity and increased circulatory lifetimes than pure sesamol.
    Type: Application
    Filed: February 6, 2007
    Publication date: January 8, 2009
    Inventor: Barry D. Sears
  • Patent number: 6140304
    Abstract: A method and nutritional and pharmaceutical compositions are provided for the reduction of hyperinsulinemia and the improvement of disease conditions related to hyperinsulinemia by administering a nutritional composition to modify hormonal response.
    Type: Grant
    Filed: December 24, 1992
    Date of Patent: October 31, 2000
    Assignee: Eicotech Corporation
    Inventor: Barry D. Sears
  • Patent number: 5059622
    Abstract: The modulation of prostaglandin levels can be realized through the dietary intake of specified ratios of activated Omega 6 essentially fatty acids when combined with the appropriate amount of eicosapentaenoic acid (EPA), an Omega 3 fatty acid. The modulation of prostaglandins levels can be determined by changes in physiological parameters which are related to prostaglandin levels in mammals. Certain ratios of activated Omega 6 essentially fatty acids and EPA can have significant physiological benefits, whereas other ratios demonstrate detrimental physiological effects in mammals.
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: October 22, 1991
    Assignee: BioSyn, Inc.
    Inventor: Barry D. Sears
  • Patent number: 4534899
    Abstract: Synthetic phospholipid compounds and their method of preparation, which compounds are phosphatidylethanolamine polycarboxyl polyalkylene glycols and are prepared by the reaction of a phosphatidylethanolamine, a polycarboxylic acid, such as succinic or glutaryl anhydride, and a polyalkylene glycol, such as polyethylene glycol.
    Type: Grant
    Filed: March 7, 1983
    Date of Patent: August 13, 1985
    Assignee: Lipid Specialties, Inc.
    Inventor: Barry D. Sears
  • Patent number: 4507217
    Abstract: Liquid magnetic compositions suitable for use in coating a substrate, such as a tape or a disc, for the preparation of magnetic memory devices, which liquid composition comprises finely-divided magnetic particles, optionally a binder for the magnetic particles, a dispersing agent for the magnetic particles and a volatile liquid solvent, the dispersing agent comprising a synthetic phosphatidyl ethanolamine polymer.
    Type: Grant
    Filed: May 12, 1983
    Date of Patent: March 26, 1985
    Assignee: Lipid Specialties, Inc.
    Inventor: Barry D. Sears
  • Patent number: 4426330
    Abstract: Novel synthetic phospholipid compounds, the compounds having the structural formula: ##STR1## where X is a hydrogen or alkyl group, n can vary from about 0 to 200, m can vary from 2 to 10, and R.sub.1 and R.sub.2 are saturated or unsaturated acyl radicals.
    Type: Grant
    Filed: July 20, 1981
    Date of Patent: January 17, 1984
    Assignee: Lipid Specialties, Inc.
    Inventor: Barry D. Sears
  • Patent number: 4320121
    Abstract: A method of emulsifying water insoluble compounds particularly cholesterol, cholesterol esters and triglycerides in the blood which method comprises emulsifying the water insoluble compound with a novel synthetic phosphatidyl quaternary ammonium, sulfonium and phosphonium hydroxide compounds or emulsifying agents which compounds have a hydrophobic/hydrophilic balance different from the natural phosphatidylcholine, by changes in the polar group.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: March 16, 1982
    Inventor: Barry D. Sears
  • Patent number: 4190628
    Abstract: A kit for determining the level of LDL cholesterol in body fluids is disclosed which contains a plant lectin which is a specific agglutinating agent for LDL.
    Type: Grant
    Filed: October 26, 1978
    Date of Patent: February 26, 1980
    Assignee: Trustees of Boston University
    Inventor: Barry D. Sears
  • Patent number: 4145410
    Abstract: A method of preparing a controlled-release pharmaceutical compound for oral administration, which pharmaceutical compound is subject to enzymatic hydrolysis on oral administration, which method comprises encapsulating the pharmaceutical compound with a synthetic phosphatidyl compound having a modified polarhead moiety which increases the resistance of the phosphatidyl compound to phospholipase C hydrolysis.
    Type: Grant
    Filed: June 17, 1977
    Date of Patent: March 20, 1979
    Inventor: Barry D. Sears
  • Patent number: 4126416
    Abstract: A method for determining the level of LDL cholesterol in blood plasma wherein LDL cholesterol is separated from other soluble cholesterol fractions by selectively agglutinating LDL with a plant lectin and subsequently detecting the amount of cholesterol associated with agglutinated LDL.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: November 21, 1978
    Assignee: The Trustees of Boston University
    Inventor: Barry D. Sears
  • Patent number: 4097503
    Abstract: Novel synthetic phosphatidyl phosphonium hydroxide compounds are prepared which have a hydrophobic/hydrophilic balance different from the natural phosphatidylcholine, which alterations are carried out by changes in the quaternary phosphonium polar group to provide different surfactant properties.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: June 27, 1978
    Inventor: Barry D. Sears
  • Patent number: RE30748
    Abstract: Novel synthetic phosphatidyl ammonium hydroxide compounds are prepared which have a hydrophobic/hydrophilic balance different from the natural phosphatidylcholine, which alterations are carried out by changes in the quaternary ammonium polar group to provide different surfactant properties.
    Type: Grant
    Filed: November 13, 1979
    Date of Patent: September 22, 1981
    Inventor: Barry D. Sears
  • Patent number: RE31609
    Abstract: A method of preparing a controlled-release pharmaceutical compound for oral administration, which pharmaceutical compound is subject to enzymatic hydrolysis on oral administration, which method comprises encapsulating the pharmaceutical compound with a synthetic phosphatidyl compound having a modified polarhead moiety which increases the resistance of the phosphatidyl compound to phospholipase C hydrolysis.
    Type: Grant
    Filed: December 14, 1979
    Date of Patent: June 19, 1984
    Assignee: Lipid Specialties, Inc.
    Inventor: Barry D. Sears