Patents by Inventor Bassam B. Damaj
Bassam B. Damaj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10632086Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: GrantFiled: December 15, 2017Date of Patent: April 28, 2020Assignee: NEXMED HOLDINGS, INC.Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20180333377Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: ApplicationFiled: December 15, 2017Publication date: November 22, 2018Applicant: NEXMED HOLDINGS, INC.Inventors: Daniel W. FRANK, Richard MARTIN, Bassam B. DAMAJ
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Patent number: 9855231Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: GrantFiled: July 29, 2016Date of Patent: January 2, 2018Assignee: NEXMED HOLDINGS, INC.Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Patent number: 9517218Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: GrantFiled: January 7, 2015Date of Patent: December 13, 2016Assignee: NEXMED HOLDINGS, INC.Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20160331761Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: ApplicationFiled: July 29, 2016Publication date: November 17, 2016Applicant: Nexmed Holdings, Inc.Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20160220524Abstract: Compositions containing a small molecule therapeutic and an alkyl N,N-disubstituted amino acetate are disclosed. Inclusion of the alkyl N,N-disubstituted amino acetate enhances the pharmacokinetic properties of the small molecule therapeutic.Type: ApplicationFiled: January 29, 2015Publication date: August 4, 2016Inventors: Bassam B. Damaj, Richard M. Martin
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Publication number: 20160081954Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: ApplicationFiled: January 7, 2015Publication date: March 24, 2016Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20150265709Abstract: Therapeutic peptide compositions comprise a therapeutic peptide, such as insulin, together with an alkyl N,N-disubstituted amino acetate, such as dodecyl 2-(N,N-dimethylamino)propionate.Type: ApplicationFiled: June 4, 2015Publication date: September 24, 2015Applicant: NEXMED HOLDINGS, INC.Inventors: Bassam B. Damaj, Richard Martin
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Publication number: 20150079163Abstract: The present disclosure provides antimicrobial compounds, compositions comprising such antimicrobial compounds, and methods of their use, in particular, antibacterial compounds and antifungal compounds. In certain aspects, the antimicrobial compounds are effective against pathogens of hospital-acquired infections. In certain aspects, the antimicrobial compounds are effective against pathogens that are resistant to antibiotics. The antimicrobial compounds can be used in antibacterial compositions, antifungal compositions, antiseptic compositions and disinfectant compositions. The antimicrobial compounds can be used as adjuncts in antibacterial compositions and antifungal compositions.Type: ApplicationFiled: September 25, 2014Publication date: March 19, 2015Inventors: Bassam B. DAMAJ, Richard Martin
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Patent number: 8962595Abstract: Compositions containing a small molecule therapeutic and an alkyl N,N-disubstituted amino acetate are disclosed. Inclusion of the alkyl N,N-disubstituted amino acetate enhances the pharmacokinetic properties of the small molecule therapeutic.Type: GrantFiled: May 4, 2011Date of Patent: February 24, 2015Assignee: Nexmed Holdings, Inc.Inventors: Bassam B. Damaj, Richard Martin
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Patent number: 8940794Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: GrantFiled: April 6, 2012Date of Patent: January 27, 2015Assignee: Nexmed Holdings, Inc.Inventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20140357713Abstract: The present disclosure provides antimicrobial compounds, compositions comprising such antimicrobial compounds, and methods of their use, in particular, antibacterial compounds and antifungal compounds. In certain aspects, the antimicrobial compounds are effective against pathogens of hospital-acquired infections. In certain aspects, the antimicrobial compounds are effective against pathogens that are resistant to antibiotics. The antimicrobial compounds can be used in antibacterial compositions, antifungal compositions, antiseptic compositions and disinfectant compositions. The antimicrobial compounds can be used as adjuncts in antibacterial compositions and antifungal compositions.Type: ApplicationFiled: May 7, 2014Publication date: December 4, 2014Applicant: NexMed Holdings, Inc.Inventors: Bassam B. Damaj, Richard Martin
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Patent number: 8900625Abstract: The present disclosure provides antimicrobial compounds, compositions comprising such antimicrobial compounds, and methods of their use, in particular, antibacterial compounds and antifungal compounds. In certain aspects, the antimicrobial compounds are effective against pathogens of hospital-acquired infections. In certain aspects, the antimicrobial compounds are effective against pathogens that are resistant to antibiotics. The antimicrobial compounds can be used in antibacterial compositions, antifungal compositions, antiseptic compositions and disinfectant compositions. The antimicrobial compounds can be used as adjuncts in antibacterial compositions and antifungal compositions.Type: GrantFiled: March 15, 2013Date of Patent: December 2, 2014Assignee: Nexmed Holdings, Inc.Inventors: Bassam B. Damaj, Richard M. Martin
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Publication number: 20140350482Abstract: The present invention relates to methods for reconstituting and relates to reconstitution devices suitable for reconstituting many different materials. Furthermore, the present invention includes methods of treatment and methods of use related to a reconstitution device or apparatus. Some embodiments are suitable for reconstituting small amounts of a pharmaceutical compositions and using the pharmaceutical composition for the treatment of sexual dysfunction.Type: ApplicationFiled: July 6, 2012Publication date: November 27, 2014Inventors: Bassam B. Damaj, Richard Martin, Michael Mueller, Daniel W. Frank
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Publication number: 20140200274Abstract: In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.Type: ApplicationFiled: April 6, 2012Publication date: July 17, 2014Applicant: Nexmed Holdings, IncInventors: Daniel W. Frank, Richard Martin, Bassam B. Damaj
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Publication number: 20140170207Abstract: The present disclosure provides antimicrobial compounds, compositions comprising such antimicrobial compounds, and methods of their use, in particular, antibacterial compounds and antifungal compounds. In certain aspects, the antimicrobial compounds are effective against pathogens of hospital-acquired infections. In certain aspects, the antimicrobial compounds are effective against pathogens that are resistant to antibiotics. The antimicrobial compounds can be used in antibacterial compositions, antifungal compositions, antiseptic compositions and disinfectant compositions. The antimicrobial compounds can be used as adjuncts in antibacterial compositions and antifungal compositions.Type: ApplicationFiled: March 15, 2013Publication date: June 19, 2014Inventors: Bassam B. Damaj, Richard M. Martin
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Patent number: 8697629Abstract: A method of treating a disease characterized by aberrant cell migration and/or invasion includes administering to a subject an effective amount of the peptide of SEQ ID NO:3, an ?6 polypeptide, or an isolated polypeptide consisting essentially of the Link region of human CD44 as indicated in FIG. 17 to modulate a FAK signal transduction pathway for a sufficient period of time to treat the disease. A method of diagnosing a condition characterized by aberrant cell migration and/or invasion includes measuring the effect of these polypeptides on FAK signal transduction activity; wherein a change in FAK signal transduction activity is indicative of said aberrant cell migration or invasion. A method of diagnosing a condition characterized by aberrant cell migration and/or invasion includes imaging FAK signal transduction activity in the presence of these polypeptides.Type: GrantFiled: March 4, 2011Date of Patent: April 15, 2014Assignee: Angstrom Pharmaceuticals, Inc.Inventors: Malcolm Finlayson, Bassam B. Damaj
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Publication number: 20130267562Abstract: 2R-dodecyl 2-(N,N dimethylamino)-propionate (R-DDAIP) provides an unexpectedly improved activity in facilitating transport of a pharmaceutically active compound across biological membranes and tissues, compared to S-DDAIP of the same enantiomeric purity, or racemic DDAIP. Purified S-DDAIP is also provided.Type: ApplicationFiled: November 30, 2011Publication date: October 10, 2013Applicant: NEXMED HOLDINGS, INCInventors: Bassam B. Damaj, Richard Martin
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Publication number: 20130210766Abstract: Compositions containing a small molecule therapeutic and an alkyl N,N-disubstituted amino acetate are disclosed. Inclusion of the alkyl N,N-disubstituted amino acetate enhances the pharmacokinetic properties of the small molecule therapeutic.Type: ApplicationFiled: May 4, 2011Publication date: August 15, 2013Applicant: NEXMED HOLDINGS, INC.Inventors: Bassam B. Damaj, Richard Martin
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Publication number: 20130209393Abstract: Therapeutic peptide compositions comprise a therapeutic peptide, such as insulin, together with an alkyl N,N-disubstituted amino acetate, such as dodecyl 2-(N,N-dimethylamino) propionate.Type: ApplicationFiled: May 4, 2011Publication date: August 15, 2013Applicant: NEXMED HOLDINGS, INC.Inventors: Bassam B. Damaj, Richard Martin