Patents by Inventor Bazbek DAVLETOV

Bazbek DAVLETOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BONDED NEUROTOXINS
    Publication number: 20230028019
    Abstract: The present invention provides novel neurotoxins and compositions comprising the same. The neurotoxins are useful in therapy, particularly for preventing, regulating or reducing neuropathic pain or sweating. Methods and kits for producing the neurotoxins are also provided.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Inventors: Bazbek DAVLETOV, Charlotte Michelle LEESE
  • Stable VAMP reporter assay
    Patent number: 11345945
    Abstract: The present invention provides a polypeptide comprising an N-terminal polypeptide domain having luciferase activity and a C-terminal polypeptide domain having VAMP1, VAMP2 or VAMP3 activity where VAMP stands for vesicle-associated membrane protein. Corresponding nucleic acid molecules, expression vectors and genetically modified cells are also provided. The invention also provides methods and uses of the same.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: May 31, 2022
    Assignee: The University Of Sheffield
    Inventors: Bazbek Davletov, Andrew Alexander Peden, Aleksander Mikael Rudolf Rust, Ciara Louise Doran
  • STABLE VAMP REPORTER ASSAY
    Publication number: 20200024639
    Abstract: The present invention provides a polypeptide comprising an N-terminal polypeptide domain having luciferase activity and a C-terminal polypeptide domain having VAMP1, VAMP2 or VAMP3 activity where VAMP stands for vesicle-associated membrane protein. Corresponding nucleic acid molecules, expression vectors and genetically modified cells are also provided. The invention also provides methods and uses of the same.
    Type: Application
    Filed: February 14, 2018
    Publication date: January 23, 2020
    Applicant: THE UNIVERSITY OF SHEFFIELD
    Inventors: Bazbek Davletov, Andrew Alexander Peden, Aleksander Mikael Rudolf Rust, Ciara Louise Doran
  • COMPLEXING SYSTEM
    Publication number: 20110038892
    Abstract: The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.
    Type: Application
    Filed: August 11, 2010
    Publication date: February 17, 2011
    Applicants: MEDICAL RESEARCH COUNCIL, ROYAL HOLOLOWAY AND BEDFORD NEW COLLEGE
    Inventors: Bazbek DAVLETOV, Frederic DARIOS, Enrico FERRARI, Mikhail SOLOVIEV