Abstract: Detection device and nucleic acid extraction method are disclosed. The detection device includes body chamber including first and second surfaces oppositely arranged, cover, piston rotatable plate and piston. The first surface is open. Sub-chambers are provided in circumferential direction of body chamber. End of each sub-chamber away from first surface has first opening. The cover is arranged on the first surface and has second opening connecting first sub-chamber. The piston rotatable plate includes cylindrical structure connected to the second surface, and includes first and second accommodating chambers connected via connecting channel along axial direction of the cylindrical structure. Third surface of the piston rotatable plate facing the body chamber includes at least one third opening connecting the first accommodating chamber.

Abstract: The present disclosure provides a microfluidic chip configured to extract a nucleic acid, the microfluidic chip including: a first substrate having at least two buffer areas configured to cooperate with a magnet, and being provided with a microfluidic channel, wherein the microfluidic channel includes a primary flow channel and a plurality of buffer flow channels connected in series to the primary flow channel, the buffer flow channels are in the buffer areas, different buffer flow channels are in different buffer areas, respectively, and each of the buffer flow channels has a double-spiral shape; and a second substrate opposite to the first substrate. The microfluidic chip has a plurality of openings in communication with the primary flow channel. The present disclosure further provides a nucleic acid extraction apparatus and a nucleic acid extraction method.

Abstract: A control valve structure, a using method thereof, a microfluidic chip, and a nucleic acid extraction device. The control valve structure includes: a cover plate layer, a first channel layer, a first adhesive layer, a second channel layer, at least one valve core, and at least one elastic film. When the valve core is embedded in the first limiting hole, the elastic film seals the first limiting hole, and the second limiting hole, the first through hole and the liquid outlet channel form a sample liquid flow channel; and when the valve core is embedded in the second limiting hole, the elastic film seals the second limiting hole so as to block the sample liquid flow channel.

Abstract: A chip heat sink for a chip and a nucleic acid extraction device, where the chip has a channel for conveying a fluid, and on/off of the channel is controlled by an solenoid valve, the chip heat sink includes: a substrate, where the substrate has a first surface for placing the chip, and the first surface is provided with a first accommodating groove for accommodating an electromagnet; and a heat dissipation structure on the substrate and for dissipating heat from the electromagnet.

Abstract: A control valve structure, a using method thereof, a microfluidic chip, and a nucleic acid extraction device. The control valve structure includes: a cover plate layer, a first channel layer, a first adhesive layer, a second channel layer, at least one valve core, and at least one elastic film. When the valve core is embedded in the first limiting hole, the elastic film seals the first limiting hole, and the second limiting hole, the first through hole and the liquid outlet channel form a sample liquid flow channel; and when the valve core is embedded in the second limiting hole, the elastic film seals the second limiting hole so as to block the sample liquid flow channel.

Abstract: The present disclosure provides a detection chip, including: a micro-cavity-defining layer having a plurality of micro-pores extending through the micro-cavity-defining layer are arranged; and a ventilative liquid-resistant layer on a side of the micro-cavity-defining layer and completely covering openings on a side of the plurality of micro-pores. The ventilative liquid-resistant layer is configured to allow gas to pass therethrough and to block liquid from passing therethrough. The present disclosure also provides a method for manufacturing a detection chip and a sample introduction method for the detection chip.

Abstract: A device and a driving method for driving a microfluidic chip are disclosed. The device for driving a microfluidic chip includes a carrying member configured to carry the microfluidic chip; a releasing member configured to electrically connected to the microfluidic chip, and control the release of the reagent of the microfluidic chip a valve control member configured to control the opening and closing of the flow channel in the valve control area of the microfluidic chip when the valve control area is within the valve control range of the valve control member a fluid driving member configured to drive the flow of fluid in the microfluidic chip, and a controller configured to control the driving process of the microfluidic chip.

Abstract: The present disclosure provides a microfluidic chip including a plurality of microcavities, at least two of the plurality of microcavities have different volumes.