Patents by Inventor Benedetto Marelli

Benedetto Marelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160215103
    Abstract: This application relates to silk fibroin particles that are structurally uniform. Related methods are also disclosed.
    Type: Application
    Filed: September 26, 2014
    Publication date: July 28, 2016
    Inventors: Fiorenzo Omenetto, Giovanni Perotto, Benedetto Marelli, David Kaplan, Alexander Mitropoulos
  • Publication number: 20160089854
    Abstract: The present invention provides, among other things, compositions including a first silk fibroin layer, and a second silk fibroin layer, wherein at least a portion of the first silk fibroin layer is directly adhered to at least a portion of the second silk fibroin layer to form a silk-silk interface and methods of making the same.
    Type: Application
    Filed: May 23, 2014
    Publication date: March 31, 2016
    Applicant: Tufts University
    Inventors: Florenzo G. Omenetto, Mark Brenckle, Benedetto Marelli, David L. Kaplan, Hu Tao
  • Publication number: 20160046138
    Abstract: The present invention provides compositions and methods for printing a predetermined pattern on silk fibroin materials using water based “inks.” Such technique may be useful for micro- and nano-engineering applications.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 18, 2016
    Inventors: Fiorenzo G. Omenetto, David L. Kaplan, Miaomiao Yang, Hu Tao, Benedetto Marelli, Sunghwan Kim
  • Publication number: 20160033861
    Abstract: The present application provides novel methods for the fabrication of nanostructures. More specifically, the invention relates to direct electron beam lithography with the use of silk fibroin as “green” resists.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Fiorenzo G. Omenetto, David L. Kaplan, Sunghwan Kim, Benedetto Marelli
  • Publication number: 20150307728
    Abstract: The present application discloses biopolymer-based ink formulations that are useful for inkjet printing and other applications. Related methods are also disclosed.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 29, 2015
    Inventors: Fiorenzo Omenetto, David Kaplan, Hu Tao, Benedetto Marelli, Miaomiao Yang
  • Publication number: 20150182660
    Abstract: There is provided a method for preparing a dense hydrogel comprising providing an at least partially gelled hydrogel, placing the at least a partially gelled hydrogel in fluid communication with an end of a capillary, and driving the at least partially gelled hydrogel into the capillary to form a dense hydrogel. There is also provided a system for preparing the dense hydrogel comprising a capillary having a bore; and a driver in communication with an end of the capillary for driving an at least partially gelled hydrogel into the bore of the capillary to form a dense hydrogel.
    Type: Application
    Filed: August 9, 2013
    Publication date: July 2, 2015
    Inventors: Showan Nazhat, Benedetto Marelli, Chiara Ghezzi, Neysan Nejat Oliver Kamranpour
  • Publication number: 20140086874
    Abstract: A method for making a biomaterial comprising providing at least one polypeptide fraction chymotryptically isolated and extracted from fibroin, and adding the at least one extracted polypeptide fraction to a hydrogel precursor before gelling, wherein the at least one isolated and extracted polypeptide fraction is selected from a soluble fraction Cs, and a precipitated fraction Cp. A biomaterial comprising at least one of the isolated and extracted polypeptide fractions incorporated in a hydrogel or a hydrogel precursor. Use of the biomaterial for constructing, regenerating, repairing, replacing or augmenting soft or hard tissue; as an in vitro or in vivo construct; as a coating material; or as a cell, molecule or particle delivery medium. Use of the isolated and extracted polypeptide fraction Cs for promoting osteoinduction, osteoconduction or osteogenesis. Use of the isolated and extracted polypeptide fraction Cp for enhancing a mechanical compressive modulus of a material into which it is incorporated.
    Type: Application
    Filed: February 28, 2012
    Publication date: March 27, 2014
    Applicants: INNOVHUB-STAZIONI SPERIMENTALI PER L'INDUSTRIA, MCGILL UNIVERSITY
    Inventors: Showan N. Nazhat, Benedetto Marelli, Giuliano Freddi, Antonio Alessandrino