Patents by Inventor Benoît Rondot

Benoît Rondot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them
    Patent number: 8476455
    Abstract: The invention relates to the compounds of formula (I): in which R1, R2, R3, R4, Q and Z are as defined in the specification. The invention also relates to the pharmaceutical compositions containing these compounds.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: July 2, 2013
    Assignee: Laboratoire Theramex
    Inventors: Jean Lafay, Benoit Rondot, Paule Bonnet, Thierry Clerc, Jacqueline Shields, Igor Duc, Eric Duranti, Francois Puccio, Christian Blot, Philippe Maillos
  • Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents
    Patent number: 8173679
    Abstract: The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 8, 2012
    Assignee: Laboratoire Thermamex
    Inventors: Benoit Rondot, Jean Lafay, Paule Bonnet, Thierry Clerc, Igor Duc, Eric Duranti, Francois Puccio, Jacqueline Shields, Christian Blot, Philippe Maillos
  • INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS
    Publication number: 20110237624
    Abstract: The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Applicant: LABORATOIRE THERAMEX
    Inventors: Benoit RONDOT, Jean LAFAY, Paule BONNET, Thierry CLERC, Igor DUC, Eric DURANTI, François PUCCIO, Jacqueline SHIELDS, Christian BLOT, Philippe MAILLOS
  • Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents
    Patent number: 7977364
    Abstract: The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: July 12, 2011
    Assignee: Laboratoire Thermamex
    Inventors: Benoit Rondot, Jean Lafay, Paule Bonnet, Thierry Clerc, Igor Duc, Eric Duranti, Francois Puccio, Jacqueline Shields, Christian Blot, Philippe Maillos
  • SULFAMATOBENZOTHIOPHENE DERIVATIVES
    Publication number: 20100168217
    Abstract: The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in claim 1, to the preparation thereof and to the use thereof as medicaments. The compounds (I) are inhibitors of steroid sulfatase and are used for the treatment of cancer.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 1, 2010
    Applicant: MERCK PATENT GMBH
    Inventors: Wolfgang Staehle, David Bruge, Gerald Scholz, Benoit Rondot, Jean Lafay
  • SULFAMATOBENZOTHIOPHENE DERIVATIVES
    Publication number: 20090286863
    Abstract: The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in Claim 1, to the preparation thereof and to the use thereof as medicaments. The compounds (I) are inhibitors of steroid sulfatase and are used for the treatment of cancer.
    Type: Application
    Filed: June 5, 2007
    Publication date: November 19, 2009
    Inventors: David Bruge, Wolfgang Staehle, Gerald Scholz, Benoit Rondot, Jean Lafay
  • Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents
    Publication number: 20090023779
    Abstract: The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
    Type: Application
    Filed: October 14, 2005
    Publication date: January 22, 2009
    Applicant: Laboratoire Theramex
    Inventors: Benoit Rondot, Jean Lafay, Paule Bonnet, Thierry Clerc, Igor Duc, Eric Duranti, Francois Puccio, Jacqueline Shields, Christian Blot, Philippe Maillos
  • Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors
    Patent number: 7476691
    Abstract: The present invention relates to sulfamate benzothiophene compounds of the formula: (I) wherein R1, R2, R3, m and n are as defined in the specification. The invention also relates to pharmaceutical compositions containing these compounds and to methods of using them.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: January 13, 2009
    Assignee: Laboratoire Theramex
    Inventors: Jean Lafay, Benoît Rondot, Denis Carniato, Paule Bonnet, Thierry Clerc, Jacqueline Shields, Igor Duc, Eric Duranti
  • 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them
    Publication number: 20070112009
    Abstract: The invention relates to the compounds of formula (I): in which R1, R2, R3, R4, Q and Z are as defined in the specification. The invention also relates to the pharmaceutical compositions containing these compounds.
    Type: Application
    Filed: December 15, 2004
    Publication date: May 17, 2007
    Inventors: Jean Lafay, Benoit Rondot, Paule Bonnet, Thierry Clerc, Jaqueline Shields, Igor Duc, Eric Duranti, Francois Puccio, Christian Blot, Philippe Maillos
  • Process for preparing medrogestone
    Publication number: 20060178520
    Abstract: A method for preparing medrogestone by heterogeneously palladium-catalyzed isomerization from 17?-methyl-6-methylenepregn-4-ene-3,20-dione.
    Type: Application
    Filed: January 17, 2006
    Publication date: August 10, 2006
    Applicant: Solvay Pharmaceuticals GmbH
    Inventors: Jean-Luc Moutou, Benoit Rondot, Jean Lafay, Philippe Maillos
  • .alpha.-phenoxy-alkanols, their methods of preparation and their applications
    Patent number: 6090984
    Abstract: New .alpha.-phenoxy-alkanols represented by the general formula ##STR1## in which R.sup.1 and R.sub.2, which may be identical or different, represent a hydrogen atom or the CH.sub.3 radical, and their stereoisomers of R,S conformation when they contain at least one asymmetric carbon.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: July 18, 2000
    Assignee: CFPI Agro
    Inventors: Joseph Schapira, Jean-Claude Cheminaud, Jean-Jacques Gasse, Vincent Schanen, Benoit Rondot, Jean-Claude Lemoine
  • Process for 3,4-disubstituted dinitroanilines
    Patent number: 6028226
    Abstract: Preparation process for 3,4-disubstituted dinitroanilines of formula ##STR1## in which, R.sub.1 and R.sub.2, which are identical to or different from one another, represent a hydrogen atom, a C.sub.1 to C.sub.6 saturated, linear or branched alkyl radical, a C.sub.2 to C.sub.6 linear or branched alkylene radical, a cyclopropyl radical or a chloroethyl radical,R.sub.3 and R.sub.4, which are identical to or different from one another are chosen from the group containing the chlorine atom, the amino group, the C.sub.1 to C.sub.3 lower alkyl radicals and the trifluoromethyl radical,comprising successively a dinitration stage of a 3,4-disubstituted phenol, an alkylation stage of the dinitrated derivative thus obtained and an amination stage of the 3,4-disubstituted 2,6-dinitro-alkoxybenzene thus obtained.
    Type: Grant
    Filed: April 7, 1998
    Date of Patent: February 22, 2000
    Assignee: Cfpi Agro
    Inventors: Joseph Schapira, Jean-Claude Cheminaud, Jean-Jacques Gasse, Vincent Schanen, Benoit Rondot, Jean-Claude Lemoine
  • Preparation process for 4-substituted dinitroanilines
    Patent number: 5981800
    Abstract: Preparation process for 4-substituted dinitroanilines of formula ##STR1## in which R.sub.1 is chosen from the group containing the tert-butyl, sulphonamido, trifluoromethyl, methyl-sulphonyl and isopropyl radicals,R.sub.2 and R.sub.3, which are identical to or different from one another, represent a hydrogen atom, a linear or branched alkyl, cycloalkyl, haloalkyl or alkenyl radical containing less than 6 carbon atoms, characterized in that that it comprises successively:a dinitration stage of the 4-substituted phenol corresponding to the sought 4-substituted dinitro-aniline, this dinitration stage being carried out in a reaction medium containing a slight excess of nitrating agent, a sufficient quantity of protons and a catalyst chosen from the group containing the soluble salts of the transition metals of columns IV to XII of the Periodic Table, preferably the soluble salts of Fe.sub.III, Fe.sub.II, Zn.sub.II and Cu.sub.
    Type: Grant
    Filed: April 7, 1998
    Date of Patent: November 9, 1999
    Assignee: CFPI Agro
    Inventors: Joseph Schapira, Jean-Claude Cheminaud, Jean-Jacques Gasse, Vincent Schanen, Benoit Rondot, Jean-Claude Lemoine