Patents by Inventor Bernd Kühn

Bernd Kühn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11077021
    Abstract: The disclosure provides a two-chamber carpule comprising two-chambers adapted to be joined together. Each chamber is adapted to contain a medicament component. The carpule further comprises a bevel arranged on a circumference of at least one of the chambers in a transition area. The bevel extends from one chamber to the other chamber.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: August 3, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Bernd Kühn, Jörn Möckel, Werner Seiferlein
  • Publication number: 20210001053
    Abstract: A stopper for use in a cartridge or syringe of a medical device [SL6]is configured to be disposed within a container closure system. The stopper comprises a shell comprising a closed end and an open end with sidewalls extending between the closed end and the open end along a longitudinal axis of the shell. The open end defines a cavity and the sidewalls define an exterior surface sized and shaped to fit inside the container closure system. An insert is configured to be inserted into the cavity, receive a force from a plunger rod, and distribute the force to the shell in order to advance the shell into the container closure system. The closed end of the shell in the cavity defining a convex surface configured to be contacted and deflected by the insert upon insertion into the cavity includes an elastic and/or plastic deformable material.
    Type: Application
    Filed: February 8, 2019
    Publication date: January 7, 2021
    Inventor: Bernd Kuehn
  • Publication number: 20200330694
    Abstract: Implementations of the present disclosure are directed to an injection device (102) that includes a medicament reservoir (103), a stopper (105) including a rigid core (125) and an ultrasound probe (122) disposed in a housing, the ultrasound probe configured to transmit an emitted ultrasound signal through the rigid core along a longitudinal direction of the rigid core into the medicament reservoir and to receive an ultrasound signal generated by reflections of the emitted ultrasound signal, the reflections including at least a reflection from a distal end of the medicament reservoir, a control component (124a) configured to be electronically coupled with the ultrasound probe and to process the ultrasound signal to generate injection device data, and an antenna (124c) configured to be electronically coupled with the control component and to transmit the injection device data to an external computing device (104).
    Type: Application
    Filed: November 12, 2018
    Publication date: October 22, 2020
    Inventors: Bernd Kuehn, Michael Schabbach, Dietmar Hammen
  • Publication number: 20200225306
    Abstract: A method for operating a magnetic resonance device is provided. The magnetic resonance device includes a component that has an operating limit in relation to a state parameter. The component uses a protocol to record magnetic resonance data. The protocol includes a magnetic resonance sequence and is described by protocol parameters. A protocol parameter set that, in relation to a protocol section, allows the protocol section to be repeated as often as desired without exceeding the operating limit is provided or determined. The method includes receiving a boost parameter from a user interface. At least for the protocol section, adaptation parameters are determined at least partially automatically based on the boost parameter, such that the desired number of repetitions described by the boost parameter is established while complying with the operating limit. Magnetic resonance data is recorded with the protocol using the determined adaptation parameters.
    Type: Application
    Filed: January 15, 2020
    Publication date: July 16, 2020
    Inventors: Thorsten Feiweier, Andreas Greiser, David Grodzki, Bernd Kühn, Mathias Nittka, Dominik Paul, Thorsten Speckner
  • Publication number: 20200054837
    Abstract: Embodiments of the present disclosure are directed to conserving energy of an injection device that includes an energy source, an electronic component configured to be electrically decoupled from the energy source, a priming component configured to generate a trigger, and a mechanism attached to the priming component and configured to perform operations comprising in response to receiving the trigger, electrically coupling the energy source to the electronic component.
    Type: Application
    Filed: April 27, 2018
    Publication date: February 20, 2020
    Inventor: Bernd Kuehn
  • Publication number: 20190262233
    Abstract: The disclosure provides a two-chamber carpule comprising two-chambers adapted to be joined together. Each chamber is adapted to contain a medicament component. The carpule further comprises a bevel arranged on a circumference of at least one of the chambers in a transition area. The bevel extends from one chamber to the other chamber.
    Type: Application
    Filed: February 9, 2017
    Publication date: August 29, 2019
    Inventors: Bernd Kühn, Jörn Möckel, Werner Seiferlein
  • Patent number: 10281545
    Abstract: In a magnetic resonance apparatus and an operating method therefore, a data acquisition sequence for operating the apparatus is repeatedly reviewed in a number of ascertainment passes executed in a processor, each ascertainment pass involving a calculation step, and in each calculation step a determination is made as to other respective values of data elements used in a previous calculation step have changed. If no change has occurred, a re-calculation in the current calculation step is not implemented, thereby reducing the time and computing capacity that are needed to generate a final data acquisition sequence.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 7, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Simon Bauer, Bernd Kuehn, Thomas Loeffler, Dominik Paul, Daniel Nico Splitthoff
  • Patent number: 10241175
    Abstract: In a method for operating a medical imaging examination apparatus having multiple subsystems controlled by a control computer in a scan sequence, a control protocol for the scan is provided to the control computer, which determines sequence control data for the control protocol that define different functional subsequences of the scan, with different effective volumes assigned to each functional subsequence. Current ambient conditions of the apparatus are determined that are decisive for the determined relevant sequence control data and associated effective volumes. Control signals for the scan are determined from the sequence control data, the effective volumes and the current ambient conditions determined that optimize the functional subsequences of the scan.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: March 26, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thomas Loeffler, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff, Stephan Stoecker, Johann Sukkau, Michael Wullenweber
  • Patent number: 10191131
    Abstract: In a method for operating a medical imaging apparatus having subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes, for a series of states of physiological processes that occur during the scan sequence. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions per observed state, that optimize the functional subsequences of the scan sequence locally.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 29, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Peter Speier
  • Patent number: 10168407
    Abstract: In a method for operating a medical imaging apparatus having multiple subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions that optimize the functional subsequences of the scan sequence locally, at least with regard to a sub-region of the respective effective volumes.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 1, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Peter Speier
  • Patent number: 10114097
    Abstract: In a method for operating a medical imaging examination apparatus having multiple subsystems, current ambient conditions in a scan volume of the apparatus are determined and stored in a global ambient condition parameter set. A control computer starts a scan sequence according to a selected scan protocol, and sequence control data that define different functional sub-sequences for the respective subsystems are provided to the control computer. Different effective volumes are assigned to each functional sub-sequence, and respective current sub-regions in the effective volume associated with the respective sub-sequence are determined, in which a volume optimization is to take place. Control signals for the scan sequence are calculated using the sequence control data, the global ambient condition parameter set, and the determined current sub-regions of the affected volumes, in order to optimize the functional sub-sequences at least with regard to the current sub-region of the assigned effective volume.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 30, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff, Michael Wullenweber
  • Patent number: 10101425
    Abstract: In a method for operating a medical imaging apparatus having subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes, for a series of states of physiological processes that occur during the scan sequence. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions per observed state, that optimize the functional subsequences of the scan sequence locally.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 16, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff
  • Patent number: 10061001
    Abstract: In a method for determining time windows in a scan sequence, in which values of setting parameters of a scan can be changed during a current scan without adversely affecting the scan data obtained with the scan, comprising the following a scan sequence is loaded into a control computer, that then determines the time windows in the scan sequence in which values of setting parameters can be changed during a current scan, on the basis of an analysis of useful coherences in the scan sequence. The determined time windows are stored or processed so as to be available to operate an imaging apparatus to execute the scan sequence.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: August 28, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff
  • Patent number: 9993464
    Abstract: The invention relates to a pharmaceutical composition comprising methyl (2R.3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]amino}butanoate or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable acidic reacting compound or to an aqueous solution or dispersion of the composition as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: June 12, 2018
    Assignee: SANOFI
    Inventors: Walter Kamm, Till Bussemer, Doris Andert, Bernd Kuehn, Ernst-Josef Todt
  • Patent number: 9835703
    Abstract: In a method to determine a complete parameter of a pulse sequence composed of multiple pulse sequence modules for operating a magnetic resonance examination apparatus parameter information of the pulse sequence modules is stored in a memory in leaves and nodes of a tree structure, and the parameter information stored in the tree structure is evaluated to determine the complete parameter of the pulse sequence.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: December 5, 2017
    Assignee: Siemens Aktiengesellschaft
    Inventor: Bernd Kuehn
  • Publication number: 20170224668
    Abstract: The invention relates to a pharmaceutical composition comprising methyl (2R.3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]amino} butanoate or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable acidic reacting compound or to an aqueous solution or dispersion of the composition as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.
    Type: Application
    Filed: September 14, 2016
    Publication date: August 10, 2017
    Inventors: Walter KAMM, Till BUSSEMER, Doris ANDERT, Bernd KUEHN, Ernst-Josef TODT
  • Patent number: 9651644
    Abstract: In a method and a magnetic resonance (MR) system, a marked area is determined that demarcates a predetermined volume segment of the subject relative to the regions adjacent thereto. Nuclei in the predetermined volume segment are excited, or nuclei in a region adjacent thereto are saturated with an RF excitation pulse at the same time a magnetic field gradient is activated. The center frequency of a frequency range of the RF excitation pulse and the direction of the magnetic field gradient are adjusted dependent on resonant frequencies of substances present within the predetermined volume segment in order, starting from the predetermined volume segment to shift an actual excitation volume segment excited by the RF excitation pulse toward the marked area, or to shift a saturation volume saturated by the RF excitation pulse away from the marked area. MR data are then acquired from the predetermined volume segment.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: May 16, 2017
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thorsten Feiweier, Christof Krellmann, Bernd Kuehn, Dominik Paul, Josef Pfeuffer, Elisabeth Preusche, Katrin Wohlfarth
  • Patent number: 9599689
    Abstract: In a method and apparatus for automatic magnetic resonance imaging of a patient, an MR overall image is composed from several MR partial images. An MR overview image is received by a process that determines several scanning ranges based on the MR overview image. The MR scanning ranges are characterized by a length along a first direction. For all MR scanning ranges: the length along the first direction is set equal to the length of the longest MR scanning range in the first direction.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: March 21, 2017
    Assignee: Siemens Aktiengesellschaft
    Inventors: Wilhelm Horger, Bernd Kuehn, Andre de Oliveira
  • Patent number: 9453896
    Abstract: In a method and apparatus for magnetic resonance (MR) imaging, a magnetization of nuclear spins in a subject is prepared in multiple preparation modules of an acquisition sequence. MR signals are acquired with at least one imaging module of the sequence. Spoiler gradient fields are generated in the multiple preparation modules in order to affect a transverse magnetization of the spins. The spoiler gradient fields that are applied in at least two different preparation modules are spatially varied along different directions. Spoiler gradient moments of the spoiler gradient fields are selected so that, for at least one of three orthogonal spatial directions, a weighted sum of the spoiler gradient moments that are applied along this spatial direction satisfies a threshold condition.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: September 27, 2016
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thorsten Feiweier, Bernd Kuehn
  • Patent number: 9365306
    Abstract: A sterile packaging system for use in the manufacture and sale of combination medical product preferably one that is attachable to an injection system to co-deliver at least two medicaments is disclosed where a tray grid comprises sterile receptacles that are removably connected, sealable and configured for use in an automated drug filling and assembly line.
    Type: Grant
    Filed: August 24, 2011
    Date of Patent: June 14, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Bernd Kühn, Werner Seiferlein