Patents by Inventor Bernhard B. Sterling
Bernhard B. Sterling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10905342Abstract: Methods, associated algorithms, and systems for determining cardiac and/or cardiovascular performance from three measurements on a subject are presented, where two of the measurements are provided by plethysmographs and one measurement is provided by an electrocardiogram. The two plethysmographs are placed different distances from the subject's heart. Certain embodiments use the three measurements to calculate intermediate variables of a left ventricular ejection time and a pre-ejection period.Type: GrantFiled: July 3, 2014Date of Patent: February 2, 2021Assignee: Cardiac Profiles, Inc.Inventors: Bernhard B. Sterling, Andrew R. Lawrence, Gregory I. Voss, James M. Perry, Rankin A. Clinton, III
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Publication number: 20200187839Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: December 9, 2019Publication date: June 18, 2020Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 10499841Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: March 1, 2018Date of Patent: December 10, 2019Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20180317828Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: March 1, 2018Publication date: November 8, 2018Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 9907504Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: August 1, 2016Date of Patent: March 6, 2018Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20170172480Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: August 1, 2016Publication date: June 22, 2017Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 9404852Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: July 18, 2014Date of Patent: August 2, 2016Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20150168294Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: July 18, 2014Publication date: June 18, 2015Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20140323891Abstract: Methods, associated algorithms, and systems for determining cardiac and/or cardiovascular performance from three measurements on a subject are presented, where two of the measurements are provided by plethysmographs and one measurement is provided by an electrocardiogram. The two plethysmographs are placed different distances from the subject's heart. Certain embodiments use the three measurements to calculate intermediate variables of a left ventricular ejection time and a pre-ejection period.Type: ApplicationFiled: July 3, 2014Publication date: October 30, 2014Inventors: Bernhard B. Sterling, Andrew R. Lawrence, Gregory I. Voss, James M. Perry, Rankin A. Clinton, III
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Patent number: 8834382Abstract: A method for determining a cardiac function, comprising (i) determining base anatomical characteristics associated with the subject, (ii) determining pulse delay to a first body site (PD01) and a second body site (PD02) as a function of the anatomical characteristics, wherein the distance via the arterial tree from the aortic valve to the first body site (PD01) is different than the arterial tree distance from the aortic valve to the second body site (PD02), (iii) determining pulse wave velocity between the first body site and the second body site (PWV12), (iv) determining pulse wave velocity between the aortic valve and the first body site (PWV01) as a function of PWV12, and the anatomical characteristics; and (v) determining the pre-ejection period (PEP) as a function of PD01 and PWV01.Type: GrantFiled: January 23, 2008Date of Patent: September 16, 2014Assignee: Cardiac Profiles, Inc.Inventors: Gregory I. Voss, James M. Perry, Rankin A. Clinton, III, Bernhard B. Sterling, Andrew R Lawrence
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Patent number: 8786838Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: March 16, 2012Date of Patent: July 22, 2014Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 8620397Abstract: A method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement. The method reduces the error in the analyte concentration in the presence of interferents. The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations. From a sample measurement, which may or may not be one of the population, likely present interferents are identified, and a calibration vector is calculated.Type: GrantFiled: October 5, 2009Date of Patent: December 31, 2013Assignee: OptiScan Biomedical CorporationInventors: Bernhard B. Sterling, W. Dale Hall, Kenneth G. Witte, Mark Wechsler, Peng Zheng, Richard Keenan
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Publication number: 20130245663Abstract: An ingestible gastric device comprising a formed body that is adapted to expand upon exposure to a hydration medium and then degrade after a first residence time in the stomach cavity, allowing the device to be passed by the patient's normal digestive process, and monitoring means for monitoring the gastric device. In some embodiments, the monitoring means comprises a biocompatible RFID tag.Type: ApplicationFiled: May 1, 2013Publication date: September 19, 2013Applicant: Plensat, Inc.Inventors: Houston Fredrick Voss, Bernhard B. Sterling
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Publication number: 20120330115Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: March 16, 2012Publication date: December 27, 2012Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 8251907Abstract: In certain embodiments, a method of maintaining health of a patient uses an analyte detection system. The analyte detection system is coupled to the patient such that a bodily fluid of the patient is accessible to the analyte detection system. The method includes automatically initiating and conducting a measurement of an analyte in the bodily fluid using the analyte detection system. The method further includes determining a treatment dose for the patient based on the measurement using the analyte detection system.Type: GrantFiled: February 8, 2010Date of Patent: August 28, 2012Assignee: OptiScan Biomedical CorporationInventors: Bernhard B. Sterling, James R. Braig, Peter Rule, Richard A. King
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Patent number: 8140140Abstract: An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.Type: GrantFiled: December 21, 2005Date of Patent: March 20, 2012Assignee: OptiScan Biomedical CorporationInventors: Bernhard B. Sterling, James R. Braig, Kenneth G. Witte, Peter Rule, Richard Keenan, W. Dale Hall
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Patent number: 8139207Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: August 15, 2011Date of Patent: March 20, 2012Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20110300619Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: ApplicationFiled: August 15, 2011Publication date: December 8, 2011Inventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 7999927Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: January 14, 2011Date of Patent: August 16, 2011Assignee: Optiscan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20110112383Abstract: An ingestible gastric device comprising a formed body that is adapted to expand upon exposure to a hydration medium and then degrade after a first residence time in the stomach cavity, allowing the device to be passed by the patient's normal digestive process, and monitoring means for monitoring the gastric device. In some embodiments, the monitoring means comprises a biocompatible RFID tag.Type: ApplicationFiled: January 4, 2011Publication date: May 12, 2011Inventors: Houston Fredrick Voss, Bernhard B. Sterling