Abstract: This invention relates to novel sulfoximine substituted quinazoline derivatives of formula I wherein Ar, R1 and R2 are as defined in the description and claims, and their use as MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) kinase inhibitors, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment or amelioration of MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) mediated disorders.

Abstract: A micromechanical rotation rate sensor has at least one first and one second seismic mass coupled to at least one first drive device and are suspended such that the first and second seismic masses are driven such that they are deflected in antiphase in one drive mode, with the rotation rate sensor being designed such that it can detect rotation rates about at least two mutually essentially orthogonal sensitive axes, wherein at least the first and second seismic masses are designed and suspended such that they oscillate in antiphase in a first read mode when a first rotation rate about the first sensitive axis is detected, and the first and second seismic masses and/or additional seismic masses are designed and suspended such that they oscillate in antiphase in a second read mode when a second rotation rate about the second sensitive axis is detected.

Abstract: A micromechanical rotation rate sensor, including a substrate whose base surface is aligned parallel to the x-y plane of a Cartesian coordinate system, with the rotation rate sensor having at least one first seismic mass and a second seismic mass which are coupled to at least one first drive device and are suspended such that the first and the second seismic masses are driven such that they are deflected in antiphase in one drive mode, with the rotation rate sensor being designed such that it can detect rotation rates about at least two mutually essentially orthogonal sensitive axes, wherein at least the second seismic mass is in the form of a frame which at least partially surrounds the first seismic mass with respect to the position on the x-y plane.

Abstract: The present inventions relate to substituted piperazine derivatives of general formula (I) and to the manufacture of said compounds, pharmaceutical compositions comprising a compound according to general formula (I), and the use of said compounds for the treatment of various medical conditions related to glycine transporter-1 (GlyT1).

Abstract: This invention relates to novel sulfoximine substituted quinazoline derivatives of formula I wherein Ar, R1 and R2 are as defined in the description and claims, and their use as MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) kinase inhibitors, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment or amelioration of MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) mediated disorders.

Abstract: A method for filtering data in a tire pressure monitoring system for a vehicle includes the steps of: recording a variable that is dependent on the tire radius for a wheel of the vehicle, and filtering the variable that is dependent on the tire radius on the basis of driving dynamics data and/or a global navigation satellite system signal, called GNSS signal below. A vehicle control system and a vehicle having the control system are also described.

Abstract: A micromechanical component formed from, a substrate (100) having a first cavity (112) and a second cavity (113), a first micromechanical structure (117) arranged in the first cavity (112), and a second micromechanical structure (118) arranged in the second cavity (113). The first cavity (112) and the second cavities having respective first and second gas pressures having different values. The first gas pressure is provided by a closed configuration of the first cavity (112) and a first channel (115) opens into the second cavity (113), and the second gas pressure is adjustable via the first channel (115).

Abstract: A storage or transport container for gasoline or similar hydraulic media, which tend to form explosive mixtures of air or gas and vapors. The container includes an electrically conductive plastic. The interior chamber of the container is substantially filled with an explosion-protection filling made of very highly thermally conductive material having a small displacement volume and a large surface.

Abstract: A micromechanical element (123a) having a plurality of individual sensor elements (1?a, 2?a, 3?a, 23a), wherein a first physical measurement variable can be measured with a first individual sensor element (1?a, 2?a, 3?a, 23a) and a second physical measurement variable can be measured with a second individual sensor element (1?a, 2?a, 3?a, 23a). A component is provided having at least one control electronics unit (1?b, 2?b, 3?b) which can be connected electrically to the micromechanical element (123a); wherein the micromechanical element (123a) and the control electronics unit (1?b, 2?b, 3?b) are arranged in a common housing (123c). A method for producing the component is further described.

Abstract: A micromechanical rotation rate sensor, comprising at least one substrate, wherein the rotation rate sensor has at least a first and a second seismic mass which are coupled to one another by means of at least one coupling beam, and wherein the rotation rate sensor is embodied in such a way that it can detect rotation rates about at least a first and a second sensitive axis, wherein each seismic mass is assigned at least one actuator unit with which the deflection behavior of the seismic mass can be influenced.

Abstract: A method and apparatus for the precise measuring operation of a micromechanical rotation rate sensor, including at least one deflectively suspended seismic mass, at least one drive device for driving the seismic mass, and at least one first and one second trimming electrode element, which are jointly assigned directly or indirectly to the seismic mass, a first electrical trimming voltage (UTO1, UTLO1, UTRO1) being set between the first trimming electrode element and the seismic mass, and a second electrical trimming voltage (UTO2, UTLO2, UTRO2) being set between the second trimming electrode element and the seismic mass, the first and the second electrical trimming voltages being set at least as a function of a quadrature parameter (UT) and a resonance parameter (Uf).

Abstract: A micromechanical acceleration sensor, including at least one substrate, one or more frames, at least a first frame of which is suspended directly or indirectly on the substrate by at least one spring element, and is deflected with respect to the substrate when at least a first acceleration acts, and at least a first seismic mass which is suspended on the first frame or an additional frame by at least one spring element, and is deflected with respect to this frame when an acceleration acts which is, in particular, different from the first acceleration.

Abstract: In order to be able to perform redundant measurements of rotation rates particularly economically, disclosed herein is a sensor device which includes a dual-axis, first rotation rate sensor element with which rotation rates of rotating motions of the sensor device about a first and a second rotation rate measurement axis can be detected, wherein the first and the second rotation rate measurement axes are oriented orthogonally in relation to one another. The sensor device is defined by the fact that the sensor device includes at least one other rotation rate sensor element with which a rotation rate of a rotating motion of the sensor device about a rotation rate measurement axis, which lies in a plane together with the first and the second rotation rate measurement axes, can be deselected.

Abstract: A device and a method for producing individual blanks from a foil web and their transport are disclosed. The foil web is fed with a first conveyor to a device for producing at least one potential parting line. The formed individual blanks are transferred with a second conveyor and fed for further processing. A tear in the individual blank is formed in the area of a guide system of the second conveyor.

Abstract: A micromechanical rotation rate sensor including at least one substrate, wherein the base surface of the substrate is oriented parallel to the x-y plane of a Cartesian coordinate system, at least two seismic masses and in each case at least one suspension spring element for suspending the seismic mass from the substrate, wherein the at least two seismic masses are coupled to one another by at least one coupling bar, and at least one of the suspension spring elements includes at least two bar sections, which, in the undeflected state, are oriented essentially parallel to one another or are at an angle of less than 45° with respect to one another, and one or more connecting sections, which connect the bar sections to one another, wherein the bar sections can be displaced relative to one another in their longitudinal direction.

Abstract: A sensor device for detecting a motion state of a motor vehicle. The sensor device includes at least one laser unit having a light source for emitting coherent light which is transmitted in the direction of a roadway surface, and an interference detector which is designed to detect at least one measurement variable which characterizes interference between the light scattered at the surface and the light of the light source. The measurement variable represents a speed component of the sensor device and/or a distance between the sensor device and the roadway surface. The laser unit is coupled to an evaluation device which is designed to determine, from the measurement variable, at least one variable which characterizes the motion state of the vehicle, in particular a speed component of the center of gravity of the vehicle, a rotational angle or a rotation rate of the vehicle.

Abstract: A micromechanical rotational rate sensor includes a substrate, at least one base element suspended by at least one spring element on the substrate, an excitation device and a read-out arrangement. The base element includes at least one seismic or inertial mass. The spring element is movable perpendicularly to the motion direction of the base element so that apex or deflection points of the spring element will move perpendicularly to the excitation direction while the base element is thereby not excited to move perpendicularly to the excitation direction.

Abstract: The invention relates to a sensor system including a plurality of sensor elements which are designed so that the elements detect at least partially different primary measured values and utilize at least partially different measurement principles, further including a signal processing apparatus, an interface apparatus and a plurality of functional apparatuses. The sensor elements are connected to the signal processing apparatus, which is designed so that it includes at least one of the following signal processing functions each for at least one of the sensor elements and/or the output signals thereof, an error handling, a filtering, a calculation and/or provision of a derived measured value. At least one measured value is derived from at least one primary measured value of one or more sensor elements, and all functional apparatuses are connected to the signal processing apparatus via the interface apparatus and the signal processing apparatus provides the signal processing functions.

Abstract: A micromechanical rotation rate sensor, including a substrate whose base surface is aligned parallel to the x-y plane of a Cartesian coordinate system, with the rotation rate sensor having at least one first seismic mass and a second seismic mass which are coupled to at least one first drive device and are suspended such that the first and the second seismic masses are driven such that they are deflected in antiphase in one drive mode, with the rotation rate sensor being designed such that it can detect rotation rates about at least two mutually essentially orthogonal sensitive axes, wherein at least the second seismic mass is in the form of a frame which at least partially surrounds the first seismic mass with respect to the position on the x-y plane.

Abstract: A method of coupling asynchronous process interaction between computer systems integrated within an overall system of interconnected systems includes receiving a set of information describing an invocation call for execution of a first process on a first system integrated within the overall system; correlating a first callback argument received upon completion of the first process that includes a first unique identifier for the first process generated by the first system with the set of information according to the first unique identifier for the first process; and sending a notification message to a callback endpoint in a second process implemented to receive notification upon completion of the first process by the first system indicating completion of the first process. The second process executing on a second system integrated within the overall system makes the invocation call. The set of information specifies the first unique identifier and the callback endpoint.