Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.

Abstract: The present invention provides a crosslinkable prepolymer which can be used to produce crosslinked polymeric materials (or contact lenses containing the same) having a high strength and excellent durability. The present invention relates to a polyvinyl alcohol-based prepolymer containing a unit having a pendant 1,2-diol containing group and a unit having a specific crosslinkable functional group, as well as a molding using the same.

Abstract: There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 ?m relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

Abstract: The present invention provides a crosslinkable prepolymer which can be used to produce crosslinked polymeric materials (or contact lenses containing the same) having a high strength and excellent durability. The present invention relates to a polyvinyl alcohol-based prepolymer containing a unit having a pendant 1,2-diol containing group and a unit having a specific crosslinkable functional group, as well as a molding using the same.

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.

Abstract: There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 ?m relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

Abstract: There is described a composition for forming an contact lens, in particular for forming a silicone hydrogel contact lens, comprising at least one first vinylic monomer or macromer having one first ethylenically unsaturated group and at least one second vinylic monomer or macromer having one second ethylenically unsaturated group, wherein the first and second ethylenically unsaturated groups are different from each other and wherein the composition further comprises a crosslinker with at least two ethylenically unsaturated (polymerizable) groups with a selected kinetic copolymerization parameter r1 of less than 1.0 relative to one of the first and second ethylenically unsaturated (polymerizable) groups as defined above.

Abstract: There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 ?m relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The invention is concerned with the problem that with known plastic casting molds, especially those of polypropylene, the lenses produced with these molds have a slippery surface. The invention solves this problem through the use of polymers which are notable for their very low oxygen permeability.

Abstract: The invention provide a class of actinically-crosslinkable silicone-containing prepolymers which comprise dangling polysiloxane chains each having a terminal ethylenically-unsaturated group and are obtained in a one-step of RAFT polymerization of a reactive mixture comprising a polysiloxane crosslinker, a hydrophilic vinylic monomer, a RAFT agent, and a free-radical initiator. The present invention is also related to silicone hydrogel contact lenses made from a prepolymer of the invention and methods for making the contact lenses in a cost-effective way and with high consistency and high fidelity to the original lens design.

Abstract: There is described a composition for forming an contact lens, in particular for forming a silicone hydrogel contact lens, comprising at least one first vinylic monomer or macromer having one first ethylenically unsaturated group and at least one second vinylic monomer or macromer having one second ethylenically unsaturated group, wherein the first and second ethylenically unsaturated groups are different from each other and wherein the composition further comprises a crosslinker with at least two ethylenically unsaturated (polymerizable) groups with a selected kinetic copolymerization parameter r1 of less than 1.0 relative to one of the first and second ethylenically unsaturated (polymerizable) groups as defined above.

Abstract: The invention relates to a process for the manufacture of a hydrophilic coating on a biomedical article, which comprises treating the biomedical article for a time period of ?5 minutes with a solution of an organic solvent comprising a polyanionic compound with a number average molecular weight Mn of >5000, wherein the solution comprises less than 10% by weight of water, and wherein the solution is devoid of a cationic polymer. The coated biomedical articles obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus especially useful in the field of ophthalmic devices.

Abstract: The present invention relates to a process for effectively curing a lens forming material to form a lens, preferably a contact lens. In particular the present invention relates to a modulated UV/VIS irradiation curing process, preferably using UV light, wherein the lens forming material is first cured with a very high intensity for a first short time period and then with a significantly lower intensity for a significantly longer time period.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: A measured amount of a material that is crosslinkable by impingement of a suitable form of energy, especially UV light, is introduced into a two-part mould of which the cavity determines the shape of a moulding to be produced. The two mould halves are held a small distance from one another so that a thin annular gap is formed between them, which gap is in communication with the mould cavity and through which gap excess material can escape. The crosslinking is triggered by impingement of the selected form of energy, the impingement being spatially restricted to the cavity by suitable masking so that material disposed outside the mould cavity is not crosslinked. In that manner mouldings are obtained that do not require subsequent mechanical processing, and the mould is reusable. The process is especially, but not, however, exclusively, suitable for the manufacture of contact lenses.

Abstract: There is described a method of separating excess lens forming material from a molded ophthalmic lens, in particular a contact lens. After polymerization and/or cross-linking of a lens forming material (P) within a mold cavity (4) of a mold (1) comprising female and male mold halves (2, 3) to form an ophthalmic lens non-polymerized and/or non-cross-linked lens forming material is flushed away from the mold halves (2, 3) with a jet of a fluid flushing medium, such as, e.g., water or a solvent or an inert gas. Subsequently the molded lens is dried. In accordance with the invention the flushing is accomplished with the mold halves (2, 3) still in the closed position. There is also described an apparatus for carrying out the method.