Patents by Inventor Betty Jin

Betty Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10195226
    Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: February 5, 2019
    Assignee: Australian Biomedical Company Pty Ltd.
    Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
  • Publication number: 20180264128
    Abstract: The present invention provides compounds for use in treating and/or preventing influenza. The compound comprises a first and second domain in which the first domain comprises at least one anchoring group which binds to the surface of influenza viruses and the second domain comprises at least one anionic group. The first and second domains are covalently linked. Also provided are pharmaceutically acceptable salts, solvates, prodrugs or stereoisomer of the compounds.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 20, 2018
    Applicant: Australian Biomedical Co. Pty Ltd.
    Inventors: Betty Jin, Ee-Ling Seah, Paul Arthur Jones, Peter James Jenkins, Henry Kenneth Windle, Wen Yang Wu
  • Publication number: 20150238512
    Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.
    Type: Application
    Filed: May 8, 2015
    Publication date: August 27, 2015
    Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
  • Patent number: 9040503
    Abstract: A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which accelerates sialyglycoconjugate biosynthesis to restore sialylglycoconjugates on the surface of the respiratory cell. Also disclosed are a method and a pharmaceutical composition, both for treating a respiratory condition.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: May 26, 2015
    Assignee: Australian Biomedical Company Pty Ltd.
    Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
  • Patent number: 8927565
    Abstract: Compositions including polymeric dialdehydes and compounds of where R1, R2, R7, R8, R9, and R10 may be the same or different and are selected from H, CH3, OH, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl; R3, R4, R5, R6 may be the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl, or R5 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R4 together are ?O, or R4 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R5 together form a double bond or are ?O, or R3 and R4, are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R5 and R6 together are ?O; R11 and R12 together form ?CH2, or R11 and R12 may be the same or different and are independently selected from the group consisting of H, CH3, CH2CH3 and CH2CH2CH3; and X is selected from the group consisting of Cl, Br, SO4, I and R13COO,
    Type: Grant
    Filed: August 26, 2004
    Date of Patent: January 6, 2015
    Assignee: Australian Biomedical Company Pty. Ltd.
    Inventors: Betty Jin, Wen-Yang Wu
  • Publication number: 20120142619
    Abstract: The present invention relates to a method and compounds of Formula (1) and/or (2) or their pharmaceutically acceptable inorganic or organic salt thereof, and their compositions for treating respiratory conditions including post viral/bacterial infections, acute/chronic bronchitis, COPD, cystic fibrosis, and inflammatory conditions. It has been found by the applicants that the compounds of Formula (1) and/or (2) or their pharmaceutically acceptable inorganic or organic salt thereof could speed up the recovery of the viability of damaged respiratory tract cells by restoring sialylglyco-conjugates on their surface.
    Type: Application
    Filed: July 2, 2010
    Publication date: June 7, 2012
    Applicant: Australian Blomedical Company Pty Ltd,
    Inventors: Betty Jin, Paul Arthur Jones, Ee Ling Seah, Wen Yang Wu, Peter James Jenkins
  • Patent number: 7468388
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: December 23, 2008
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
  • Patent number: 7371755
    Abstract: This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: May 13, 2008
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Guy Krippner, Phillip A. Reece, Keith G. Watson, Wen-Yang Wu, Betty Jin, Simon P. Tucker
  • Publication number: 20070293564
    Abstract: A method for the prevention of an orthomyxovirus or paramyxovirus infection comprising the step of administration to a subject in need thereof of an effective amount of a compound of formula (I)
    Type: Application
    Filed: December 4, 2006
    Publication date: December 20, 2007
    Inventors: Michael Dowle, Betty Jin, Simon MacDonald, Andrew Mason, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
  • Publication number: 20070225358
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Application
    Filed: April 12, 2007
    Publication date: September 27, 2007
    Inventors: Betty JIN, Simon MacDonald, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
  • Patent number: 7223790
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2–C8 alkyl C3-8 cycloalkyl, C1–C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: May 29, 2007
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
  • Patent number: 7205333
    Abstract: The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: April 17, 2007
    Inventors: Wen-Yang Wu, Michael Dennis Dowle, Betty Jin, Simon John Fawcett Macdonald, Andrew McMurtrie Mason, Darryl McConnell, Keith Watson
  • Publication number: 20070027176
    Abstract: This invention is related to compositions including compounds of where R1, R2, R7, R8, R9, and R10 may be the same or different and are selected from H, CH3, OH, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl; R3, R4, R5, R6 may be the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl, or R5 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R4 together are ?O, or R4 and R6 are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R3 and R5 together form a double bond or are ?O, or R3 and R4, are the same or different and are selected from H, CH3, OCH3, C2H5, OC2H5OCH2Ph, OCH2PhNO2, F or Cl and R5 and R6 together are ?O; R11 and R12 together form ?CH2, or R11 and R12 may be the same or different and are independently selected from the group consisting of H, CH3, CH2CH3 and CH2CH2CH3; and X is selected from the group consisting of Cl, Br, SO4, I and
    Type: Application
    Filed: August 26, 2004
    Publication date: February 1, 2007
    Inventors: Betty Jin, Wen-Yang Wu
  • Patent number: 7157494
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, SO2NH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: January 2, 2007
    Assignee: Biota Scientific Management Pty. Ltd.
    Inventors: Michael D. Dowle, Betty Jin, Simon J. F. Macdonald, Andrew McM Mason, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
  • Patent number: 7078403
    Abstract: Disclosed herein are compounds of formula II: wherein Alk, Z, X1, X2, R1, —R10 and R11 are defined herein, and their salts and pharmaceutically acceptable derivatives thereof, as well as other compounds of the general formula Het-A-Alk-W-Ar-C(X2)?NO-X2 where Het, A, W and Ar are also defined herein. These compounds are useful in treating picornavirus infections in mammals. Novel intermediates of these compounds, as well as pharmaceutical compositions and methods of use, are also disclosed herein.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: July 18, 2006
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Wen-Yang Wu, Keith Watson, Darryl McConnell, Betty Jin, Guy Krippner
  • Publication number: 20050085413
    Abstract: The invention relates to a compound of general formula (I): X-L-Y??(I) in which X and Y are pharmaceutically active moieties which may be the same or different; and L is a linker which is an optionally substituted saturated or unsaturated straight chain, branched and/or cyclic hydrocarbon radical having a backbone of at least 11 atoms, or a pharmaceutically acceptable derivative or salt thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a microbial infection.
    Type: Application
    Filed: November 8, 2002
    Publication date: April 21, 2005
    Inventors: Betty Jin, John Lambert, Roland Nearn, Van Nguyen, Simon Tucker, Wen-Yang Wu
  • Publication number: 20050054719
    Abstract: The invention relates to compounds of general formula (1); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C8 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Application
    Filed: November 8, 2002
    Publication date: March 10, 2005
    Inventors: Betty Jin, Simon MacDonald, Darryl McConnell, Van Nguyen, Stephen Shanahan, Wen-Yang Wu
  • Publication number: 20050038108
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, SO2NH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Application
    Filed: November 8, 2002
    Publication date: February 17, 2005
    Inventors: Michael Dowle, Betty Jin, Simon Macdonald, Andrew McM Mason, Darryl Mcconnell, Van Nguyen, Stepehn Shanahan, Wen-Yang Wu
  • Publication number: 20040058853
    Abstract: The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.
    Type: Application
    Filed: October 14, 2003
    Publication date: March 25, 2004
    Inventors: Wen-Yang Wu, Michael Dennis Dowle, Betty Jin, Simon John Fawcett Macdonald, Andrew McMurtrie Mason, Darryl McConnell, Keith Watson
  • Patent number: 6680054
    Abstract: The invention provides novel macromolecules, methods for their preparation, pharmaceutical formulations thereof and their use as anti-influenza agents. The invention also provides a novel diagnostic method which can be used for detection of all types of influenza A and B virus. The macromolecular compound of the invention has attached to it one or more molecules (neuraminidase binders) which bind to the active site of influenza virus neuraminidase but which are not cleaved by the neuraminidase.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: January 20, 2004
    Assignee: Biota Scientific Management PTY Ltd.
    Inventors: Phillip A. Reece, Keith Geoffrey Watson, Wen-Yang Wu, Betty Jin, Guy Y. Krippner