Patents by Inventor Bo-Tsang Huang

Bo-Tsang Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11214774
    Abstract: The present disclosure includes a PINK1-C-terminal domain (PINK1-CTD) polypeptide that binds to ERBB tyrosine kinase domain (ERBB-TKD) and therefore impedes ERBB from dimerization and activation. The PINK1-CTD polypeptide inhibits, prevents and/or treats ERBB-expressing cancers. The disclosure demonstrates the anti-tumor function of the PINK1-CTD, which provides a new direction for ERBB-expressing cancer therapy.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: January 4, 2022
    Assignees: National Taiwan University, Academia Sinica
    Inventors: Pan-Chyr Yang, Pei-Ying Lin, Bo-Tsang Huang
  • Publication number: 20200411561
    Abstract: A display apparatus includes a wireless transmission unit and a display panel. The display panel includes a substrate, a plurality of pixel units and a signal line. The substrate includes a display region and a periphery region. The periphery region surrounds the display region. The pixel units are disposed on the display region. Each of the pixel units includes an active device and a pixel electrode. The active device is electrically connected to the pixel electrode. The signal line is on the periphery region. As viewed from a top view, the signal line has an annular shape having a gap and surrounds the display region.
    Type: Application
    Filed: June 22, 2020
    Publication date: December 31, 2020
    Inventors: Chia-Chi CHANG, Chih-Chun CHEN, Chi-Ming WU, Yi-Ching WANG, Jia-Hung CHEN, Bo-Tsang HUANG, Wei-Yueh KU
  • Patent number: 10584341
    Abstract: Aptamers that bind to and antagonize PDL1 and uses thereof in enhancing immune activity (e.g., promoting T cell proliferation), treating cancer, and/or infectious diseases such as infections caused by enterovirus, HBV, or HCV infection.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: March 10, 2020
    Assignees: Academia Sinica, National Taiwan University
    Inventors: Pan-Chyr Yang, Wei-Yun Lai, Bo-Tsang Huang
  • Patent number: 10533179
    Abstract: Aptamers that bind to and inhibit CTLA-4 and uses thereof in enhancing immune activities, and treating cancer and HIV infection are provided.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: January 14, 2020
    Assignees: Academia Sinica, National Taiwan University, Taipei Medical University
    Inventors: Konan Peck, Pan-Chyr Yang, Yi-Chung Chang, Bo-Tsang Huang, Shauh-Der Yeh
  • Publication number: 20180258431
    Abstract: Aptamers that bind to and antagonize PDL1 and uses thereof in enhancing immune activity (e.g., promoting T cell proliferation), treating cancer, and/or infectious diseases such as infections caused by enterovirus, HBV, or HCV infection.
    Type: Application
    Filed: August 31, 2016
    Publication date: September 13, 2018
    Applicants: Academia Sinica, National Taiwan University
    Inventors: Pan-Chyr Yang, Wei-Yun Lai, Bo-Tsang Huang
  • Publication number: 20180112192
    Abstract: The present disclosure includes a PINK1-C-terminal domain (PINK1-CTD) polypeptide that binds to ERBB tyrosine kinase domain (ERBB-TKD) and therefore impedes ERBB from dimerization and activation. The PINK1-CTD polypeptide inhibits, prevents and/or treats ERBB-expressing cancers. The disclosure demonstrates the anti-tumor function of the PINK1-CTD, which provides a new direction for ERBB-expressing cancer therapy.
    Type: Application
    Filed: May 2, 2016
    Publication date: April 26, 2018
    Inventors: Pan-Chyr Yang, Pei-Ying Lin, Bo-Tsang Huang
  • Publication number: 20170211067
    Abstract: Aptamers that bind to and inhibit CTLA-4 and uses thereof in enhancing immune activities, and treating cancer and HIV infection are provided.
    Type: Application
    Filed: July 31, 2015
    Publication date: July 27, 2017
    Applicants: Academia Sinica, National Taiwan University, Taipei Medical University
    Inventors: Konan Peck, Pan-Chyr Yang, Yi-Chung Chang, Bo-Tsang Huang, Shauh-Der Yeh