Patents by Inventor Bo Ye
Bo Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210041343Abstract: A blood analysis method, a blood analysis system, and a storage medium are provided. The blood analysis method includes: providing a blood sample; mixing a first aliquot of the blood sample with a diluent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample to obtain first volume distribution data; detecting at least two types of optical signals of the second test sample to obtain second volume distribution data; acquiring red blood cell test data of the blood sample; determining, based on the first volume distribution data, the second volume distribution data, and the red blood cell test data, whether the blood sample contains schistocytes; and if the determination result is yes, providing a warning that the blood sample may contain schistocytes.Type: ApplicationFiled: October 23, 2020Publication date: February 11, 2021Inventors: Bo YE, Wenbo ZHENG, Huan QI, Zhaoyang LI
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Publication number: 20210041361Abstract: A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.Type: ApplicationFiled: October 23, 2020Publication date: February 11, 2021Inventors: Huan QI, Wenbo ZHENG, Bo YE, Zhaoyang LI, Yi YE
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Publication number: 20210033592Abstract: A blood analyzer and a blood analysis method thereof are provided. The blood analyzer includes a test sample preparation apparatus, a flow chamber, a measurement apparatus and a data processor. The method adopts a white blood cell measurement channel to detect a test blood sample subjected to hemolysis and fluorescence staining and utilizes data in a blood ghost region to identify reticulocyte particles, thereby realizing differentiation of reticulocytes and large platelets and realizing finer classification and count of reticulocytes without separately designing an optical detection channel in the blood analyzer. A computer readable storage medium is also disclosed, in which a program is stored, and the program can be executed by the data processor to implement the above method.Type: ApplicationFiled: October 20, 2020Publication date: February 4, 2021Inventors: Bo YE, Huan QI, Wenbo ZHENG, Yi YE
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Publication number: 20210033593Abstract: Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system (100) and a storage medium.Type: ApplicationFiled: October 20, 2020Publication date: February 4, 2021Inventors: Huan QI, Bo YE, Wenbo ZHENG, Changsong HU, Qi YU
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Patent number: 10883916Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.Type: GrantFiled: February 26, 2020Date of Patent: January 5, 2021Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
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Publication number: 20200209218Abstract: An alarming method for a platelet aggregation sample can include providing a blood sample, preparing a first test sample from the blood sample under a first reaction condition, acquiring a test signal of the first test sample, and obtaining first platelet test data. The method can also include preparing a second test sample from the blood sample under a second reaction condition, acquiring a test signal of the second test sample, and obtaining second platelet test data. The method can further include obtaining an evaluation result based on the first platelet test data and the second platelet test data, determining whether the evaluation result meets a predetermined condition, and alarming that the blood sample may be the platelet aggregation sample if the evaluation result meets the predetermined condition. The second reaction condition may include a reaction condition for reducing the platelet aggregation degree of the blood sample.Type: ApplicationFiled: March 4, 2020Publication date: July 2, 2020Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Bo YE, Wenbo ZHENG, Huan QI, Xuerong LI
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Publication number: 20200209224Abstract: The present disclosure relates to the field of medical technology, which provides methods and apparatuses for identifying red blood cells infected by plasmodium. The methods may include: obtaining a forward-scattered light signal, a side-scattered light signal and an optional fluorescence signal from cells in a blood sample; obtaining a first two-dimensional scattergram according to the forward-scattered light signal and the side-scattered light signal, or obtaining a three-dimensional scattergram according to the forward-scattered light signal, the side-scattered light signal and the fluorescence signal; and identifying cells located in a predetermined area of the first two-dimensional scattergram or the three-dimensional scattergram as the red blood cells infected by plasmodium. The apparatuses perform the methods. The methods and apparatuses can have better identification accuracy.Type: ApplicationFiled: March 10, 2020Publication date: July 2, 2020Inventors: Bo Ye, Cheng Qian, Huan Qi
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Publication number: 20200191700Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
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Publication number: 20200191701Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
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Publication number: 20200180687Abstract: A method and system corrects steering of a vehicle upon a brake system malfunction. The brake system has a diagonal split layout. An electronic brake system (EBS) controls operation of the master cylinder. An electronic power steering system (EPS) includes sensors to measure motion and torque of a steering column of the vehicle and includes a motor to provide torque to the steering column. During driver braking when one of the brake circuits has failed, the system calculates a yaw torque value introduced by a driver braking with just one functioning brake circuit. Based on a steer wheel angle and a steer wheel torque obtained from the sensors of the EPS and on the yaw torque value, a steer wheel torque request defining a steer wheel torque/angle needed to counter the yaw torque value is calculated and sent the EPS which operates the motor to compensate for the steering deviation.Type: ApplicationFiled: December 11, 2018Publication date: June 11, 2020Applicant: Continental Automotive Systems, Inc.Inventors: Bo Ye, Pedro Henriques, Naren Dhansri
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Patent number: 10656143Abstract: The present disclosure relates to the field of medical technology, which provides methods and apparatuses for identifying red blood cells infected by plasmodium. The methods may include: obtaining a forward-scattered light signal, a side-scattered light signal and an optional fluorescence signal from cells in a blood sample; obtaining a first two-dimensional scattergram according to the forward-scattered light signal and the side-scattered light signal, or obtaining a three-dimensional scattergram according to the forward-scattered light signal, the side-scattered light signal and the fluorescence signal; and identifying cells located in a predetermined area of the first two-dimensional scattergram or the three-dimensional scattergram as the red blood cells infected by plasmodium. The apparatuses perform the methods. The methods and apparatuses can have better identification accuracy.Type: GrantFiled: October 31, 2012Date of Patent: May 19, 2020Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Bo Ye, Cheng Qian, Huan Qi
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Publication number: 20200130663Abstract: A method adjusts a brake pedal feedback in a brake-by-wire vehicle brake system. The brake system includes a brake pedal and a simulation device associated with the brake pedal such that in a brake-by-wire mode of operation, the simulation device provides brake pedal feedback to the driver. An input signal is provided to a processor circuit of a control unit of the brake system. The input signal relates to a desired brake pedal feedback associated with a driver of the vehicle. The processor circuit generates a brake pedal feel output signal based on data regarding vehicle deceleration vs. travel of the brake pedal and on data regarding the vehicle deceleration vs. force on the brake pedal. Based on the brake pedal feel output signal, the control unit controls an output of the simulation device to establish the desired brake pedal feedback.Type: ApplicationFiled: October 30, 2018Publication date: April 30, 2020Applicant: Continental Automotive Systems, Inc.Inventors: Bo Ye, Pedro Henriques
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Publication number: 20200132589Abstract: The present invention falls within the field of medical apparatuses. Disclosed are a method and a device for identifying platelet aggregation, and a flow cytometer, which are used for accurately giving an alarm about a platelet aggregation during blood cell analysis.Type: ApplicationFiled: December 18, 2019Publication date: April 30, 2020Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Guanzhen WANG, Bo YE, Jiantao DI
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Publication number: 20200129100Abstract: A blood detection method and a blood detection device are disclosed. When a count number of platelet in a blood sample is less than a predetermined value, a detection solution of the blood sample is prepared. A cell statistical amount of the detection solution of the blood sample is increased to obtain the platelet detection result. The cell statistics amount of the detection solution of the blood sample may be increased in an impedance detection area to perform PLT-I detection, or in an RET detection area; or performing both of RET detection and PLT-O detection simultaneously. Thus, the accuracy of platelet detection can be improved when the number of platelets in the blood sample is low.Type: ApplicationFiled: December 27, 2019Publication date: April 30, 2020Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Xuerong LI, Huilin SHI, Jianchao LIU, Bo YE
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Patent number: 10627332Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.Type: GrantFiled: May 16, 2019Date of Patent: April 21, 2020Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
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Publication number: 20190371434Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.Type: ApplicationFiled: August 15, 2019Publication date: December 5, 2019Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Bo YE, Changsong HU, Huan QI, Wenbo ZHENG
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Publication number: 20190360929Abstract: A method for identifying fragmented red blood cells comprising: acquiring side scatter light signals and fluorescence signals of cell particles in a sample liquid; and distinguishing and identifying a fragmented red blood cell population from the cell particles according to the side scatter light signals and the fluorescence signals of the cell particles. The fragmented red blood cell population can be identified from the cell particles by processing and analyzing the side scatter light signals and fluorescence signals of the sample liquid. The present application further provides a device for identifying fragmented red blood cells, a blood cell analyzer and an analysis method. Fragmented red blood cells can be identified according to the fluorescence that characterizes a nucleic acid content in a cell particle and the side scatter light, thus reducing errors in identification and counting.Type: ApplicationFiled: August 12, 2019Publication date: November 28, 2019Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Wenbo ZHENG, Bo YE, Huan QI, Shan YU, Xiujuan LI, Zhaoyang LI
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Publication number: 20190277746Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.Type: ApplicationFiled: May 16, 2019Publication date: September 12, 2019Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
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Publication number: 20190230215Abstract: According to a method for pushing a notification provided in some embodiments of the present disclosure, a to-be-notified event is obtained; a first notification condition and a second notification condition are determined; a first notification page is displayed on the display when the first notification condition is met, to display, to a user, first association information when the first notification condition is met, for example, event status information, to-be-executed behavior information, and operation association information; and a second notification page is displayed on the display when the second notification condition is met after the first notification page is displayed, to display, to the user, second association information when the second notification condition is met. A plurality of notification pages are pushed for a to-be-notified event, and each notification page is pushed when a notification condition is met as the event develops.Type: ApplicationFiled: September 9, 2016Publication date: July 25, 2019Applicant: HUAWEI TECHNOLOGIES CO.,LTD.Inventors: Guo Zhu, Dawei Li, Ning Ding, Yongning Wang, Bo Ye, Xueyan Huang
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Patent number: 10330584Abstract: A cell analyzer and a particle sorting method and device are disclosed. The method comprises: acquiring a pulse width of at least one optical signal according to a detected optical signal, selecting at least one optical signal as a combined optical signal, and respectively calculating a signal intensity of the combined optical signal with the pulse width in a combinatorial way to obtain at least one reinforcement signal, where a difference between a first category of particles and a second categories of particles in the reinforcement signal is increased relative to a difference therebetween in the combined optical signal; and on the basis of the reinforcement signal and at least another signal, forming a new scatter diagram, where the at least another signal is one of other reinforcement signals and the optical signal, distinguishing the first category of particles from the second category of particles according to the new scatter diagram.Type: GrantFiled: August 11, 2017Date of Patent: June 25, 2019Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi