Patents by Inventor Boaz Manash

Boaz Manash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11938021
    Abstract: A prosthetic heart valve has a frame including a plurality of strut members, an inflow end, and an outflow end. A leaflet structure is situated at least partially within the frame, and a covering is disposed around an exterior of the frame. The covering includes a cushioning layer, and a first strip member folded over an inflow circumferential edge portion of the cushioning layer to form a first protective portion. A second strip member is folded over an outflow circumferential edge portion of the cushioning layer to form a second protective portion. The first strip member and the second strip member are spaced apart from each other along a longitudinal axis of the prosthetic heart valve.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: March 26, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Sara Tzadok, Khen Perlmutter, Darshin S. Patel, Boaz Manash, Ajay Chadha, Waina Michelle Chu, Chambory Chhe, Evan T. Schwartz, Sandip Vasant Pawar
  • Patent number: 11931258
    Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The delivery system can include a number of advantageous steering and delivery features, in particular for the transseptal delivery approach.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: March 19, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Boaz Manash, Oren Cohen, Noam Nir, Ilan Tamir, Eitan Atias, Ofir Witzman, Michal Aliza Ruchelsman
  • Publication number: 20240074851
    Abstract: In one embodiment, a prosthetic valve assembly includes an annular frame being radially expandable and compressible between a radially compressed configuration and a radially expanded configuration, a valvular structure comprising a plurality of leaflets mounted inside the annular frame, a plurality of posts mounted on an interior surface of the annular frame, and a pair of commissure attachment members extending outwardly from each post and away from each other. Each two adjacent leaflets can form a pair of commissure tabs. Each pair of commissure tabs can be attached to a corresponding pair of the commissure attachment members.
    Type: Application
    Filed: August 18, 2023
    Publication date: March 7, 2024
    Inventors: Noam Nir, Michael Bukin, Boaz Manash
  • Patent number: 11883294
    Abstract: An anchoring system and related methods are provided for treatment of dilated hearts and of functional valve regurgitation, the system comprising one or more self-expandable or manually expandable anchors and associated devices for fixating a valve splint within the heart. For example, a spade-shaped assembly may be configured to be deployed in a right ventricle of the heart and to stabilize a puncturing instrument to puncture the septum. Various puncturing instruments may also be part of the anchoring system, including one or more of a flexible needle having a multiplicity of slits disposed along the length of the needle, a trocar catheter with a retractable head, and a catheter needle having a blunt introducer to protect nearby tissue within the heart during advancing a guidewire. A cutter catheter and puncture location catheter may also be part of the system and be used during treatment.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: January 30, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Arie Tylis, Nikolai Gurovich, Eran Goldberg, Boaz Manash, Dan Rottenberg, Hagar Adika, Tal Regev, Dikla Kersh, Danny M. Garmahi, Hernan Altman, Amir Blumenfeld
  • Patent number: 11877925
    Abstract: Systems and methods usable in delivering a docking device to a native valve of a patient's heart. A distal region of a delivery catheter can be positioned in an atrium of the heart and a distal tip can be positioned at or near a commissure of the native valve. The docking device can be located within the delivery catheter. A pusher, such as a pusher wire or tube, of a pusher tool can be advanced distally through the delivery catheter, wherein the pusher can push the docking device along within the delivery catheter. The docking device can be connected to the pusher tool by a line, such as a suture. A member of the pusher tool can be rotatable to change the amount of the suture extending from the pusher tool.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: January 23, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Boaz Manash, Yoav Rozen, Eitan Atias
  • Publication number: 20230404748
    Abstract: Systems and methods usable in delivering a docking device to a native valve of a patient's heart. A docking device can be connected to a pusher tool by a line, such as a suture. A member of the pusher tool can be rotatable to change the amount of the suture extending from the pusher tool.
    Type: Application
    Filed: July 28, 2023
    Publication date: December 21, 2023
    Inventors: Boaz Manash, Yoav Rozen, Eitan Atias
  • Patent number: 11801133
    Abstract: Docking devices for docking a prosthetic valve at a native valve of a heart can include a coiled docking anchor and a retrieval suture. The docking device and retrieval suture can be configured for improved retention and retrieval of the docking device after deployment. The docking devices can have an end portion with a central axis. The retrieval suture can be connected to the end portion such that a line of force applied by applying tension to the retrieval suture is substantially aligned with the central axis.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: October 31, 2023
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Eyal Leiba, Yoav Rozen, Dinesh L. Sirimanne, Tri D. Tran, Jocelyn Chau, Noa Axelrod Manela, Zohar Kiblitski
  • Publication number: 20230310152
    Abstract: A docking device for docking a prosthetic valve at a native valve of a heart can include a coil comprising a plurality of turns and having a proximal end and distal end. The docking device can further include a first covering disposed around and covering the coil from the distal end to the proximal end of the coil, and a second covering disposed over the first covering. A distal end and proximal end of the second covering are spaced away from a distal end and proximal end, respectively, of the first covering.
    Type: Application
    Filed: June 6, 2023
    Publication date: October 5, 2023
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Eyal Leiba, Yoav Rozen, Dinesh L. Sirimanne, Tri D. Tran, Jocelyn Chau, Noa Axelrod Manela, Zohar Kiblitski
  • Publication number: 20230285141
    Abstract: A docking device for docking a prosthetic valve at a native valve of a heart includes a coiled body and a high friction sleeve. The coiled body has an upper region, a central region, and a lower region. The docking device is configured to be implanted at the native valve with the upper region positioned in a first chamber of the heart, the lower region positioned in a second chamber of the heart, and the central region positioned to extend around a plurality of leaflets of the native valve. A high friction sleeve covers at least a portion of the central region. The high friction sleeve comprises a material configured to generate more friction between the prosthetic valve and the docking device than an exterior surface of the coiled body.
    Type: Application
    Filed: May 19, 2023
    Publication date: September 14, 2023
    Inventors: Darshin S. Patel, Hernan Altman, Boaz Manash, Tamir S. Levi, Dinesh L. Sirimanne
  • Publication number: 20230225717
    Abstract: Embodiments of the present disclosure include a device for passing a guidewire around an anatomical structure within a body, comprising a catheter including an elongated tube having at least a first lumen and a second lumen, a guidewire configured to pass through the first lumen of the catheter, and a snare configured to pass through the second lumen of the catheter. A first exit of one of the first lumen and the second lumen may be positioned at or near a distal tip of the catheter, and a second exit of another of the first lumen and the second lumen may be positioned on a side of the catheter at a distance proximal to the distal tip of the catheter. A portion of the catheter distal to the second exit may be configured to bend around at least a portion of the anatomical structure of interest within the body.
    Type: Application
    Filed: May 24, 2021
    Publication date: July 20, 2023
    Inventors: David NEUSTADTER, Boaz MANASH
  • Patent number: 11690708
    Abstract: Methods of implanting docking devices for prosthetic valves at a native heart valve include positioning a distal end of a delivery catheter into a first chamber of a heart, advancing a tubular body of a docking device from within the delivery catheter so that the distal end of the tubular body is advanced between native valve leaflets and positioned in a second chamber of the heart. The methods further include inserting a coil into a lumen of the docking device so that the tubular body adopts a configuration, releasing a proximal end of the docking device in the first chamber, inserting a replacement valve in an inner space of the docking device, and radially expanding the replacement valve until there is a retention force between the replacement valve and the docking device to hold the replacement valve in a stable position in the native valve.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: July 4, 2023
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Darshin S. Patel, Hernan Altman, Boaz Manash, Tamir S. Levi, Dinesh L. Sirimanne
  • Publication number: 20230201015
    Abstract: A docking station for a prosthetic heart valve includes a radially expandable and collapsible frame with a first plurality of struts, an inflow end portion, an outflow end portion, and a longitudinal axis. A sealing member is disposed on the outflow end portion and configured to form a seal between the docking station and a body lumen. The docking station further includes a valve seat coupled to the frame and configured to receive an expandable prosthetic valve. The valve seat includes a second plurality of struts coupled to the frame and extending in a downstream direction and angled inwardly toward the longitudinal axis of the frame.
    Type: Application
    Filed: February 17, 2023
    Publication date: June 29, 2023
    Inventors: Nikolai Gurovich, Boaz Manash, Adi Carmi, Eran Goldberg, Khen Perlmutter
  • Publication number: 20230089738
    Abstract: A prosthetic valve assembly includes a prosthetic valve and an anchoring frame. The prosthetic valve includes a valve frame and a valve structure. The valve frame includes a plurality of struts and is expandable from a compressed configuration to an expanded configuration. The valvular structure includes leaflets. The valvular structure is disposed radially within and is coupled to the valve frame. The valvular structure is configured to allow blood flow through the prosthetic valve assembly in a first direction and to restrict blood flow through the prosthetic valve assembly in a second direction. The anchoring frame includes a plurality of struts. The anchoring frame is disposed radially outwardly from and is coupled to the valve frame. The struts of the anchoring frame comprise one or more tissue-engaging elements configured for contacting native tissue to help secure the prosthetic valve assembly at an implantation location.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 23, 2023
    Inventors: Adi Carmi, Boaz Manash, Nikolai Gurovich, Michael Bukin
  • Publication number: 20230090577
    Abstract: Exemplary embodiments of devices and method for affecting at least one anatomical tissue can be provided. A configuration can be provided that includes a structure which is expandable (i) having and/or (ii) forming at least one opening or a working space through which the anatomical tissue(s) is placed in the structure. For example, the structure, prior to being expanding, can have at least one partially rigid portion. In addition, or as an alternative, upon a partial or complete expansion thereof, the structure can be controllable to have a plurality of shapes. Further, the structure can be controllable to provide the working space with multiple shapes and/or multiple sizes.
    Type: Application
    Filed: September 26, 2022
    Publication date: March 23, 2023
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Gregory Piskun, Dan Rottenberg, Boaz Manash, Dima Pinhasov
  • Publication number: 20230077068
    Abstract: Methods and tools for implanting prosthetic heart valves and modifying leaflets of an existing valvular structure in a subject are disclosed herein. Prior to or during implantation of the prosthetic heart valve within the existing valvular structure, each tool can be provided in the ascending aorta (or equivalent thereof) of a subject and can be used to pierce, lacerate, slice, tear, cut or otherwise modify a leaflet or commissure of the existing valvular structure. The existing valvular structure can be a native aortic valve or other native heart valve, or a previously-implanted prosthetic heart valve. The modification can avoid, or at least reduce the likelihood of, issues that leaflets of the existing valvular structure might otherwise cause once the prosthetic heart valve has been fully installed, for example, obstruction of blood flow to the coronary arteries and/or improper valve mounting due to a non-circular cross-section.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 9, 2023
    Inventors: Ilan Tamir, David Maimon, Hanoch Cohen-Tzemach, Adva Alon, Amir Keret, Eyal Leiba, Boaz Manash, Sean Chow, Ziv Yohanan, Shay Zarneger
  • Publication number: 20230062364
    Abstract: One embodiment of the present disclosure is directed to a selectively connectable medical device. The medical device may include a first flexible wire having an orifice on a distal end thereof and a flexible sleeve surrounding the first flexible wire. The flexible sleeve may be movable along the first flexible wire to a first orientation exposing the orifice, and a second orientation extending over the orifice. The device may further include a second flexible wire having a graspable region on an end thereof. The flexible sleeve may be configured, when the graspable region is threaded through the orifice, to be moved to the second orientation causing the graspable region to bend about an edge of the orifice, and to simultaneously cover the orifice and at least a portion of the graspable region, thereby locking the second wire to the first wire.
    Type: Application
    Filed: February 16, 2021
    Publication date: March 2, 2023
    Inventors: David NEUSTADTER, Boaz MANASH
  • Patent number: 11576784
    Abstract: An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: February 14, 2023
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yaron Keidar, W. Vaso Adzich, Dan Rottenberg, Boaz Manash, Alon Nahshon
  • Publication number: 20220401215
    Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.
    Type: Application
    Filed: August 23, 2022
    Publication date: December 22, 2022
    Inventors: Anatoly Dvorsky, Tamir S. Levi, Yair A. Neumann, Noa Axelrod Manela, Eitan Atias, Oren Cohen, Elazar Levi Schwarcz, Ofir Witzman, Noam Miller, Boaz Manash, Danny M. Garmahi
  • Patent number: 11446141
    Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: September 20, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Anatoly Dvorsky, Tamir S. Levi, Yair A. Neumann, Noa Axelrod Manela, Eitan Atias, Oren Cohen, Elazar Levi Schwarcz, Ofir Witzman, Noam Miller, Boaz Manash, Danny M. Garmahi
  • Patent number: 11446146
    Abstract: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: September 20, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Noa Axelrod Manela, Oren H. Wintner, Eran Goldberg, Dikla Kersh, Danny M. Garmahi, Dan Rottenberg, Boaz Manash