Abstract: A a composition for prevention or treatment of a Staphylococcus aureus infectious disease and a composition for prevention or treatment of a thrombotic disorder caused by Staphylococcus aureus infection are disclosed. Cell lysis by 11 toxins of Staphylococcus aureus can be thoroughly inhibited by using the cross-reactivity of antibodies against Staphylococcus aureus toxins, even with a minimal combination of antigens. The composition can be used as an effective therapeutic composition that can comprehensively remove or alleviate comprehensive pathological conditions caused by infection, away from piecemeal amelioration of individual symptoms caused by Staphylococcus aureus infection, by inducing opsonophagocytosis and effectively controlling blood coagulation in infected individuals.

Abstract: A composition containing wall teichoic acid-attached peptidoglycan (WTA-PGN) as an active ingredient, a method for preventing or treating Staphylococcus aureus infectious diseases using the composition, and a method for preparing a soluble WTA-PGN which can be used as an active ingredient in the composition are provided. The composition of the present invention can be effectively used for preventing or treating Staphylococcus aureus infectious diseases by opsonophagocytosis due to antigen-antibody reaction and neutrophil-mediated phagocytosis due to T cell activation at the early stage of infection.

Abstract: The present invention relates to a vaccine composition for preventing staphylococcus aureus infection containing, as an active ingredient, a ribitol-phosphate which has been modified only by a ?-configuration in N-Acetylglucosamine (GlcNAc), a repeating unit of the ribitol-phosphate, or a wall teichoic acid (WTA) containing the repeating unit. The composition according to the present invention contains a coupling motif (an epitope) for an anti-WTA antibody, and thus can be effectively used as a vaccine composition or to prevent staphylococcus aureus infection by generating anti-WTA antibody.

Abstract: The present invention provides novel proteins activating pro-phenoloxidase (pro-PO) system of Tenebrio molitor, genes encoding the same, methods of detecting bacterial infection in a sample using the proteins, and kits for detecting bacterial infection in a sample using the proteins. The present invention also provides a method of preparing a soluble linearized Lys-type pep-tidoglycan (SLPG), useful for a standard substance for the kit.

Abstract: The present invention provides a separate and purified peptidoglycan-recognition protein having an amino acid sequence as set forth in SEQ ID NO: 1 and also a peptidoglycan detection kit comprising the separate and purified peptidoglycan-recognition protein.

Abstract: The present invention provides novel proteins activating pro-phenoloxidase (pro-PO) system of Tenebrio molitor, genes encoding the same, methods of detecting bacterial infection in a sample using the proteins, and kits for detecting bacterial infection in a sample using the proteins. The present invention also provides a method of preparing a soluble linearized Lys-type pep-tidoglycan (SLPG), useful for a standard substance for the kit.

Abstract: The present invention relates to a composition for selectively detecting an extremely small amount of peptidoglycan in sample, a preparation method of the composition, and a detection kit for peptidoglycan. It is possible to quantify a small amount of peptidoglycan contained in human blood, tissue, body fluid, water or food, and to diagnose an infection of microorganism with peptidoglycan as a component of cell wall using the composition and the detection kit. In addition, the composition can be applied for a diagnosis reagent of detecting an infection of Gram-positive bacteria in animal or human being in advance, and thus, can be used for the prevention or treatment of food poisonings and bacterial sepsis.

Abstract: Provided is a method of separating a peptidoglycan-recognition protein from the hemolymph of Tenebrio molitor larvae, the method including: (a) preparing an affinity chromatography column by packing a column with a resin bound with at least one synthetic peptidoglycan; (b) applying the hemolymph of Tenebrio molitor larvae to the affinity chromatography column; (c) applying a mobile phase to the affinity chromatography column to obtain a peptidoglycan-recognition protein-containing solution eluted from the affinity chromatography column; and (d) purifying a peptidoglycan-recognition protein from the eluted solution.

Abstract: The present invention relates to a composition for selectively detecting an extremely small amount of peptidoglycan in sample, a preparation method of the composition, and a detection kit for peptidoglycan. It is possible to quantify a small amount of peptidoglycan contained in human blood, tissue, body fluid, water or food, and to diagnose an infection of microorganism with peptidoglycan as a component of cell wall using the composition and the detection kit. In addition, the composition can be applied for a diagnosis reagent of detecting an infection of Gram-positive bacteria in animal or human being in advance, and thus, can be used for the prevention or treatment of food poisonings and bacterial sepsis.

Abstract: The present invention relates to a composition for detecting an infinitesimal quantity of ?-1,3-glucan, a preparation method thereof and a diagnostic kit detecting ?-1,3-glucan. The composition of the present invention shows phenoloxidase activity by ?-1,3-glucan in the presence of calcium ions. Using the composition of the present invention, a sample is gathered from a specimen, the composition of the present invention and calcium ions are added to the sample, and ?-1,3-glucan is detected by measuring phenoloxidase activity.

Abstract: The present invention relates to a composition for selectively detecting an extremely small amount of peptidoglycan in sample, a preparation method of the composition, and a detection kit for peptidoglycan. It is possible to quantify a small amount of peptidoglycan contained in human blood, tissue, body fluid, water or food, and to diagnose an infection of microorganism with peptidoglycan as a component of cell wall using the composition and the detection kit. In addition, the composition can be applied for a diagnosis reagent of detecting an infection of Gram-positive bacteria in animal or human being in advance, and thus, can be used for the prevention or treatment of food poisonings and Bacterial sepsis.

Abstract: The present invention relates to a composition for detecting an infinitesimal quantity of beta-1,3-glucan, a preparation method thereof and a diagnostic kit detecting beta-1,3-glucan. The composition of the present invention shows phenoloxidase activity by beta-1.3-glucan in the presence of calcium ions. Using the composition of the present invention, a sample is gathered from a specimen, the composition of the present invention and calcium ions are added to the sample, and beta-1,3-glucan is detected by measuring phenoloxidase activity.

Abstract: The present invention relates to a protein related to encapsulation in immune reaction and a gene encoding the same.