Patents by Inventor Brandon M. Young

Brandon M. Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11395665
    Abstract: A neurovascular catheter having an atraumatic navigational tip is disclosed. The catheter includes an elongate flexible tubular body, a distal zone of the tubular body comprising: a tubular inner liner; a helical coil surrounding the inner liner and having a distal end, a tubular jacket surrounding the helical coil, and extending distally beyond the helical coil distal end to terminate in a catheter distal face, and a tubular radiopaque marker embedded in the tubular jacket. The catheter distal face comprises a first section that resides on a first plane which crosses a longitudinal axis of the tubular body at a first angle within the range of from about 35 degrees to about 55 degrees, and a second section that resides on a second plane which crosses the longitudinal axis of the tubular body at a second angle within the range from about 55 degrees to about 90 degrees.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: July 26, 2022
    Assignee: Incept, LLC
    Inventors: Yi Yang, Ashoor Shahbazi Yourgenlow, Lisa M. Young, Brandon Yee, Marc Russell, Ryan Taylor Krone
  • Publication number: 20210188777
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Patent number: 11028051
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 8, 2021
    Assignee: St. Jude Children's Research Hospital
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Patent number: 10875875
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: December 29, 2020
    Assignee: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • Publication number: 20200079739
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 12, 2017
    Publication date: March 12, 2020
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Patent number: 10494367
    Abstract: Provided herein are methods for antagonizing the action of an ?4-integrin to treat various pathophysiological conditions utilizing pharmaceutical compositions of compounds or pharmaceutically acceptable salts or stereoisomer(s) thereof of formula I where R1, R2, R3, R4, R5, X and R6 are as described herein.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: December 3, 2019
    Assignee: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Robert V. Market, Michael M. Savage, Brandon M. Young
  • Publication number: 20190225602
    Abstract: Provided herein are methods for antagonizing the action of an ?4-integrin to treat various pathophysiological conditions utilizing pharmaceutical compositions of compounds or pharmaceutically acceptable salts or stereoisomer(s) thereof of formula I where R1, R2, R3, R4, R5, X and R6 are as described herein.
    Type: Application
    Filed: April 1, 2019
    Publication date: July 25, 2019
    Applicant: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Robert V. Market, Michael M. Savage, Brandon M. Young
  • Patent number: 10246451
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5, X and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomer(s) of these compounds. In addition methods are provided for antagonizing the action of an ?4-integrin to treat various pathophysiological conditions.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: April 2, 2019
    Assignee: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Robert V. Market, Michael M. Savage, Brandon M. Young
  • Publication number: 20180312498
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5, X and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomer(s) of these compounds. In addition methods are provided for antagonizing the action of an ?4-integrin to treat various pathophysiological conditions.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 1, 2018
    Applicant: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Robert V. Market, Michael M. Savage, Brandon M. Young
  • Publication number: 20180312523
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 1, 2018
    Applicant: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • Patent number: 8178699
    Abstract: Provided are compounds that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or ameliorating diseases associated with modulation of CCR9 receptor activity.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: May 15, 2012
    Assignee: Pfizer Inc.
    Inventors: Eric C Anderson, Ronald J Biediger, Jie Chen, Brian Dupre, Pedro Lory, Robert V. Market, Keith A. Monk, Michael M. Savage, Reginald Tennyson, Brandon M. Young
  • Publication number: 20100029753
    Abstract: Provided are compounds that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or ameliorating diseases associated with modulation of CCR9 receptor activity.
    Type: Application
    Filed: July 30, 2008
    Publication date: February 4, 2010
    Inventors: Eric C. Anderson, Ronald J. Biediger, Jie Chen, Brian Dupre, Pedro Lory, Robert V. Market, Keith A. Monk, Michael M. Savage, Reginald Tennyson, Brandon M. Young