Patents by Inventor Brian A. Fox

Brian A. Fox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10570187
    Abstract: Disclosed are soluble hybrid Fc? receptor (Fc?R) polypeptide compositions and related methods of using such polypeptides to treat IgG-mediated and immune complex-mediated inflammation. Also disclosed are related compositions and methods for producing the soluble hybrid Fc?R polypeptides.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: February 25, 2020
    Assignee: ZymoGenetics, Inc.
    Inventors: Carl W. Birks, Brian A. Fox, Mark W. Rixon, Jeff L. Ellsworth
  • Patent number: 10540176
    Abstract: A computer system, method, or computer-readable medium controls a potentially unacceptable software component intended for a software repository. A pre-defined application or repository policy associated with the repository or application pre-defines risks and, for each of the risks, an action to take for the risk. The action can be a pass action or a does-not-pass action, which are pre-defined programmatic steps also defined in the policy. When the component is not new to the repository or the application, the component is passed through for the usual handling. When the component is new, risks are determined that match the software component; for risks which match, the actions are taken as defined in the pre-defined policy. The pass action can include adding the software component to the software repository. The does-not-pass action is followed for a component that does not pass as a potentially unacceptable software component.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: January 21, 2020
    Assignee: Sonatype, Inc.
    Inventors: Wayne Jackson, Michael Hansen, Brian Fox, Jaime Whitehouse, Jason Dillon
  • Patent number: 10494138
    Abstract: A container for an article includes a series of walls including a top wall that cooperate to define an interior of the container. A brace assembly is positioned toward an upper end defined by the interior of the container, and includes a brace member that is positioned below the top wall of the container and that defines opposite ends, each of which is located adjacent one of a pair of opposite sidewalls of the container. The brace assembly includes a carrier, which may be formed of a series of corrugated panels, and the brace member may be secured to a hinged brace member mounting panel such that the brace member is suspended above an upper surface of an article within the container interior and below the top wall of the container.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: December 3, 2019
    Assignee: Green Bay Packaging, Inc.
    Inventors: Jeremy Velliquette, Andrew Capogrosso, Brian Fox
  • Publication number: 20190300537
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Application
    Filed: June 7, 2019
    Publication date: October 3, 2019
    Applicant: Denali Therapeutics Inc.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cheng Hu, Maksim Osipov, Zachary K. Sweeney, Javier de Vicente Fidalgo, Arun Thottumkara
  • Publication number: 20190112318
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Application
    Filed: September 13, 2018
    Publication date: April 18, 2019
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
  • Publication number: 20190048329
    Abstract: Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, ?-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The ?-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.
    Type: Application
    Filed: August 14, 2018
    Publication date: February 14, 2019
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Timothy James Donohue, Daniel Leo Gall, Wayne S. Kontur, Hoon Kim, John Ralph, Daniel R. Noguera, Brian Fox, Craig Bingman
  • Publication number: 20180357481
    Abstract: An electronic device, computer-readable medium, and method executed by the electronic device including the steps of activating at least one camera of the electronic device, receiving one or more images of an object comprising at least one graphic printed thereon or embedded therein via the at least one camera, recognizing the at least one graphic within at least one image in the one or more images, determining a pre-programmed output in one or more pre-programmed outputs based at least in part on the recognized at least one graphic, and transmitting the pre-programmed output via one or more of at least one speaker of the electronic device or the at least one display of the electronic device.
    Type: Application
    Filed: June 12, 2018
    Publication date: December 13, 2018
    Inventors: THOMAS BROSSEAU, BRIAN FOX
  • Publication number: 20180353480
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 13, 2018
    Inventors: Giorgio Bonanomi, Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Carmela Napolitano, Alfonso Pozzan, Anantha Sudhakar, Zachary K. Sweeney, Federica Tonelli, Javier de Vicente Fidalgo
  • Patent number: 10131676
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: November 20, 2018
    Assignee: Denali Therapeutics Inc.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
  • Publication number: 20180298353
    Abstract: The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of p-coumaroyl-CoA:monolignol transferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 18, 2018
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
  • Publication number: 20180282710
    Abstract: The invention relates to feruloyl-CoA:monolignol transferase enzymes and nucleic acids encoding the feruloyl-CoA:monolignol transferase enzymes. The enzymes and/or the nucleic acids enable incorporation of monolignol ferulates into the lignin of plants. The monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate.
    Type: Application
    Filed: April 4, 2018
    Publication date: October 4, 2018
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATON
    Inventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
  • Publication number: 20180258172
    Abstract: Disclosed is a newly identified B7 family member, zB7H6, which functions as a counter-receptor for the NK cell triggering receptor, NKp30. Methods and compositions for modulating NKp30-mediated NK cell activity based on the interaction of zB7H6 with NKp30, as well as related screening methods, are also disclosed. Further disclosed are anti-zB7H6 antibodies as well as antibody-drug conjugates comprising an anti-zB7H6 antibody conjugated to a therapeutic agent, including methods for using such antibodies and antibody-drug conjugates to exert therapeutic effects against zB7H6-expressing cells.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 13, 2018
    Inventors: Cameron S. Brandt, Jacob J. Kennedy, Wenfeng Xu, Eugene C. Yi, Brian A. Fox, Zeren Gao, Pallavur V. Sivakumar
  • Patent number: 10005837
    Abstract: Disclosed is a newly identified B7 family member, zB7H6, which functions as a counter-receptor for the NK cell triggering receptor, NKp30. Methods and compositions for modulating NKp30-mediated NK cell activity based on the interaction of zB7H6 with NKp30, as well as related screening methods, are also disclosed. Further disclosed are anti-zB7H6 antibodies as well as antibody-drug conjugates comprising an anti-zB7H6 antibody conjugated to a therapeutic agent, including methods for using such antibodies and antibody-drug conjugates to exert therapeutic effects against zB7H6-expressing cells.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: June 26, 2018
    Assignee: Zymogenetics, Inc.
    Inventors: Cameron S. Brandt, Jacob J. Kennedy, Wenfeng Xu, Eugene C. Yi, Brian A. Fox, Zeren Gao, Pallavur V. Sivakumar
  • Patent number: 9971594
    Abstract: A computer system, method, or non-transitory computer-readable medium provides an authoritative name source for files within an ecosystem. Files in the ecosystem which have identical contends and similar contents to each other are merged into the same supercluster, to capture possibly incremental changes to the files over time in one of the superclusters. For each supercluster which has files with identical and similar contents, the supercluster is broken down into package clusters, based on packages to which the files belong, each of the package clusters has the files from a same package. The package cluster which has most change frequency across versions, is identified as the authoritative package. The authoritative name for the files is resolved, based on the authoritative packages that are determined, across the plurality of superclusters which have files with identical and similar contents, and the authoritative name is generated. Any authoritative name collision is resolved.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: May 15, 2018
    Assignee: Sonatype, Inc.
    Inventors: Brian Fox, Bruce Mayhew, Jamie Whitehouse, Gazi Mahmud
  • Publication number: 20180099981
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Application
    Filed: September 29, 2017
    Publication date: April 12, 2018
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
  • Publication number: 20180052682
    Abstract: A computer system, method, or non-transitory computer-readable medium provides an authoritative name source for files within an ecosystem. Files in the ecosystem which have identical contends and similar contents to each other are merged into the same supercluster, to capture possibly incremental changes to the files over time in one of the superclusters. For each supercluster which has files with identical and similar contents, the supercluster is broken down into package clusters, based on packages to which the files belong, each of the package clusters has the files from a same package. The package cluster which has most change frequency across versions, is identified as the authoritative package. The authoritative name for the files is resolved, based on the authoritative packages that are determined, across the plurality of superclusters which have files with identical and similar contents, and the authoritative name is generated. Any authoritative name collision is resolved.
    Type: Application
    Filed: August 16, 2016
    Publication date: February 22, 2018
    Inventors: Brian Fox, Bruce Mayhew, Jamie Whitehouse, Gazi Mahmud
  • Patent number: 9896458
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 20, 2018
    Assignee: Denali Therapeutics Inc.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Zachary K. Sweeney
  • Publication number: 20180022759
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
  • Patent number: 9815850
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: November 14, 2017
    Assignee: Denali Therapeutics Inc.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
  • Publication number: 20170226127
    Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
    Type: Application
    Filed: February 3, 2017
    Publication date: August 10, 2017
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo