Patents by Inventor Brian B. Masek

Brian B. Masek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,6-naphthyridinone derivatives having angiotension II antagonist activity
    Patent number: 5294620
    Abstract: The invention concerns pharmaceutically useful compounds of the formula I, in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: March 15, 1994
    Assignee: Imperial Chemical Industries PLC
    Inventors: Arnold H. Ratcliffe, Robert J. Pearce, Keith H. Gibson, Robin Wood, Brian B. Masek
  • 1,6-naphthyridone derivatives having angiotensin II antagonist activity
    Patent number: 5217976
    Abstract: The invention concerns pharmaceutically useful compounds of the formula I, in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: June 8, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: Arnold H. Ratcliffe, Robert J. Pearce, Keith H. Gibson, Robin Wood, Brian B. Masek