Abstract: This invention relates to a therapeutic composition for detection and/or treatment of mammalian tumors which comprises at least one fluorescent porphyrin containing at least three carboxylic acid groups and pharmaceutically acceptable salts thereof.

Abstract: A fluorescent mono-, di-, or tri- or tetramide between an amino acid of the formula ##STR1## and a carboxy containing tetrapyrrole of the formula: ##STR2## or the corresponding di or tetrahydrotetrapyrroles. The compounds herein are useful for the photodetection and phototreatment of tumors and/or cancerous tissues in animal hosts.

Abstract: This invention relates to new therapeutic compositions which are useful in photodiagnosis and phototherapy, especially in the detection and treatment of tumors and cancerous tissues in the human or animal body. The compounds of the present new therapeutic composition are mono-, di or polyamides of an amino monocarboxylic acid and a tetrapyrrole containing at least one carboxyl group of the structure ##STR1## wherein Z is the aminomonocarboxylic acid residue less the amino group, X is the tetrapyrrole residue less the carboxy group, and "n" is an integer from 1 to 4 inclusive.

Abstract: This invention relates to a fluorescent mono, di- or polyamide of an aminodicarboxylic acid and a tetrapyrrole containing at least three carboxy groups of the structure: ##STR1## wherein Z is the amino acid residue and X is the tetrapyrrole residue and "n" is an integer from 1 to 4 inclusive.

Abstract: The present invention relates to compounds having the following formula: ##STR1## or the corresponding di- or tetrahydrotetrapyrroles wherein ##STR2## provided that when R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.7 and R.sub.8 represent two substituents or are divalent and attached to the same carbon, the respective pyrrole ring to which attached is a dihydropyrrole;R is lower alkyl or benzyl;R.sub.6 and R.sub.9, taken together are ##STR3## with the proviso that at least one of R.sub.1 -R.sub.9 includes a free carboxyl group; and salts thereof.These compounds are useful in the photodiagnosis and phototherapy of tumors.

Abstract: This invention relates to new fluorescent mono, di- or polyamide of an aminomonocarboxylic acid and a tetrapyrrole containing at least three carboxy groups of the structure: ##STR1## wherein Z is the amino acid residue and x is the tetrapyrrole residue and "n" is an integer from 1 to 4 inclusive.