Patents by Inventor Bruce J. Simon

Bruce J. Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210085971
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a vagus nerve. The system comprises a handheld stimulator including a housing having a contact surface for contacting an outer skin surface of a patient. The housing is configured for attachment and electrical coupling to a mobile device configured to receive a wireless signal. An energy source is coupled to the stimulator and the mobile device. The energy source is configured to generate an electric field that transmits an electric current through the contact surface and the outer skin surface to modulate a nerve within the patient and thereby treat a medical condition of the patient.
    Type: Application
    Filed: November 20, 2020
    Publication date: March 25, 2021
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Publication number: 20210031026
    Abstract: Devices and methods for non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode spaced from the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is positioned within the housing and operably coupled to the electrode, either wirelessly or via a lead or other wired connection. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises bursts each with a frequency from about 1 Hz to about 100 Hz, wherein each of the bursts comprises 2 pulses to 20 pulses.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 4, 2021
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 10874857
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 29, 2020
    Assignee: ELECTROCORE, INC
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Publication number: 20200398043
    Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a spinal nerve within the patient such that the patient experiences at least some pain relief. The methods include varying an electric field such that burst periods and constant periods are created. The electric field has a charge that alternates between positive and negative during the burst periods and a charge with a magnitude of zero during the constant periods.
    Type: Application
    Filed: September 2, 2020
    Publication date: December 24, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200353240
    Abstract: Methods and devices for stimulating a nerve in a patient include positioning a device adjacent an outer skin surface of the patient and emitting an electrical field near the vagus nerve within the patient. The electric field is varied to create burst periods and constant periods. The charge of the electric field emitted during the burst periods alternates between positive and negative. The charge of the electric field emitted during the constant periods has a magnitude of zero.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 12, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200346011
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A stimulator comprises a contact surface for contacting an outer skin surface of a patient and a pulse generator coupled to the contact surface. The pulse generator is configured for attachment and electrical coupling to a mobile device configured to receive a wireless signal, such as a mobile phone. The pulse generator is further configured to generate an electrical impulse and to transmit the electrical impulse through the contact surface and the outer skin surface of the patient to modulate a nerve within the patient.
    Type: Application
    Filed: July 22, 2020
    Publication date: November 5, 2020
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Publication number: 20200246616
    Abstract: Devices and methods are provided for treating a patient that include delivering an electrical signal to a target nerve within the patient. The electrical signal has parameters selected to modulate the target nerve for therapeutic purposes to treat a disease or disorder in the patient.
    Type: Application
    Filed: April 2, 2020
    Publication date: August 6, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200246615
    Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a target nerve within the patient. The electrical signal comprises bursts with a frequency of 1 to 100 Hz. Each of the bursts has 2 to 20 pulses with a duration of about 50 microseconds to about 1000 microseconds.
    Type: Application
    Filed: April 1, 2020
    Publication date: August 6, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200246617
    Abstract: Systems and methods for reducing or inhibiting an inflammatory response in a patient include a source of energy and one or more electrodes coupled to the source of energy and positionable near a vagus nerve of the patient to deliver the electrical impulse to the vagus nerve. The electrical impulse is sufficient to either inhibit a release of a pro-inflammatory cytokine, such as TNF-alpha, or increase an anti-inflammatory competence of a cytokine, such as TGF-beta, in the patient, thereby inhibiting the inflammatory response. The electrical impulse may be delivered transcutaneously and non-invasively through an outer skin surface of the patient to the vagus nerve.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Inventors: Joseph P. Errico, Francis R. Amato, Steven M. Mendez, Hecheng Hu, Bruce J. Simon
  • Publication number: 20200230408
    Abstract: Systems and methods are provided for treating an inflammatory or allergic response associated with a replicating pathogen, such as a virus in the coronaviridae family. The methods include emitting an electrical impulse near a vagus nerve within the patient sufficient to inhibit or reduce an inflammatory or allergic response in the patient. The systems and methods of the present invention reduce the expression of inflammatory mediators that are elevated in ARDS and other inflammatory or allergic disorders, thereby ameliorating the overactivity of the immune reaction in patient's suffering from certain disorders, such as the coronavirus. This therapy may include a feedback mechanism to provide potent anti-inflammatory benefits without the negative side effects of conventional immune suppression techniques and drugs, such as steroids and other nebulized drugs.
    Type: Application
    Filed: April 2, 2020
    Publication date: July 23, 2020
    Inventors: Joseph P. Errico, Bruce J. Simon, Peter Staats, Thomas Errico
  • Publication number: 20200222695
    Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a target nerve within the patient. The electrical signal comprises bursts of about 2 to about 20 pulses and the pulses oscillate between a positive voltage and a negative voltage within each burst.
    Type: Application
    Filed: April 1, 2020
    Publication date: July 16, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200222708
    Abstract: Devices, systems and methods are provided for treating a disease or disorder in a patient. The methods incluce positioning a surface of a housing in contact with an outer skin surface of the patient and applying sufficient energy to an energy transmitter within the housing via a power supply to generate an electrical impulse at or near a vagus nerve of the patient. The the electrical impulse is sufficient to modulate fibers of the vagus nerve and treat the disease or disorder.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 16, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle, Steven Mendez
  • Publication number: 20200171304
    Abstract: Transcutaneous electrical and magnetic nerve stimulation devices are disclosed, along with methods of treating lower urinary tract disorders using energy that is delivered noninvasively by the devices. The disorders comprise overactive bladder, urge incontinence, stress, incontinence, urge frequency, non-obstructive urinary retention and interstitial cystitis/painful bladder syndrome. In embodiments of the disclosed methods, a posterior tibial nerve of a patient is stimulated non-invasively. Methods are disclosed for selecting protocol parameters for a nerve stimulation session for treating each individual patient, wherein modules of the bladder of the patient are represented as coupled non-linear oscillators.
    Type: Application
    Filed: March 18, 2019
    Publication date: June 4, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 10639490
    Abstract: Devices, systems and methods are disclosed for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease. The treatment comprises transmitting impulses of energy non-invasively to selected nerve fibers that are responsible for smooth muscle dilation. The transmitted energy impulses, comprising magnetic and/or electrical, mechanical and/or acoustic, and optical and/or thermal energy, stimulate the selected nerve fibers.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: May 5, 2020
    Assignee: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle, Steven Mendez
  • Publication number: 20200086108
    Abstract: Devices, systems and methods are disclosed for reducing inflammation associated with an aneurysm in a patient. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in the vagus nerve. Vagus nerve stimulation is used to modulate the release of neurotransmitters in the brain and to reduce inflammation that may lead to the formation, growth, rupture or hemorrhage of an aneurysm.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 19, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Publication number: 20200078589
    Abstract: Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.
    Type: Application
    Filed: October 24, 2019
    Publication date: March 12, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200054872
    Abstract: Devices, systems and methods are disclosed for treating or preventing an autism spectrum disorder, a pervasive developmental disorder, or a disorder of psychological development. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The nerve stimulation may be used as a behavior conditioning tool, by producing euphoria in an autistic individual. Vagus nerve stimulation is also used to modulate circulating serotonin levels in a pregnant woman so as to reduce the risk of having an autistic child; modulate the levels of growth factors within a child; promote balance of neuronal excitation/inhibition; modulate the activity of abnormal resting state neuronal networks; increase respiratory sinus arrhythmia; and avert episodes of motor stereotypies with the aid of forecasting methods.
    Type: Application
    Filed: October 24, 2019
    Publication date: February 20, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200046973
    Abstract: Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The devices comprise a housing and an energy source for generating an electric current and transmitting the electric current from the electrode through an interface and the outer skin surface of the patient to a selected nerve fiber within the patient as the interface contacts the outer skin surface. The electric current is sufficient to modulate the selected nerve fiber to at least one of treat or prevent at least one of gastroparesis, functional dyspepsia, or ileus in the patient.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 13, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200053487
    Abstract: Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 13, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20200046976
    Abstract: Methods and devices are disclosed for the non-invasive treatment of neurodegenerative diseases through delivery of energy to target nervous tissue, particularly the vagus nerve. The methods and devices transmit an electrical impulse transcutaneously through an outer skin surface of the patient to modulate activity of a selected nerve at the target region to inhibit inflammation, enhance an anti-inflammatory competence of a cytokine in the patient and treat the neurodegenerative disorder. The stimulation brings about reduction of neuroinflammation in patients suffering from conditions comprising Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, postoperative cognitive dysfunction and postoperative delirium.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 13, 2020
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle