Abstract: The present invention relates to a method of treatment of movement disorders, comprising administering to a patient in need thereof an effective amount of befiradol, wherein the administering step provides an average patient's maximum plasma concentration of befiradol below 15 ng/mL which occurs more than 4 hours post administration, said method minimizing side effects of dizziness and nausea. Sustained release pharmaceutical compositions that can be used according to this method are also described.

Abstract: The present invention relates to a method of treatment of movement disorders, comprising administering to a patient in need thereof an effective amount of befiradol, wherein the administering step provides an average patient's maximum plasma concentration of befiradol below 15 ng/mL which occurs more than 4 hours post administration, said method minimizing side effects of dizziness and nausea. Sustained release pharmaceutical compositions that can be used according to this method are also described.

Abstract: A method for selling seats in a movie theater, comprising the steps of: providing a first screening room in a movie theater with actuated seats providing movement in synchronization with a motion picture having a feature-length presentation being projected; selling access to non-actuated seats in the movie theater at a base price per seat; selling access to said actuated seats in said first screening room at a second price per seat, the second price being equal to the base price per seat added to an actuated-seat premium; controlling the access to said actuated seats in said first screening room as opposed to the non-actuated seats; and projecting said motion picture in the first screening room with the actuated seats being actuated to provide movement in synchronization with the motion picture.

Abstract: The present invention relates to a method of treatment of movement disorders, comprising administering to a patient in need thereof an effective amount of befiradol, wherein the administering step provides an average patient's maximum plasma concentration of befiradol below 15 ng/mL which occurs more than 4 hours post administration, said method minimizing side effects of dizziness and nausea. Sustained release pharmaceutical compositions that can be used according to this method are also described.

Abstract: The present invention relates to a method of treatment of movement disorders, comprising administering to a patient in need thereof an effective amount of befiradol, where in the administering step provides an average patient's maximum plasma concentration of befiradol below 15 ng/mL which occurs more than 4 hours post administration, said method minimizing side effects of dizziness and nausea. Sustained release pharmaceutical compositions that can be used according to this method are also described.

Abstract: A system for providing motion signals indicative of a motion to be performed by the motion platforms synchronously with video images comprising an input interface for extracting a motion signal from the input signal. A server provides a network address to each motion platform. A motion platform interface has control ports connected to arrays of motion platforms. Each motion platform being connected one to another by a wired connection according to a control protocol. The motion platform interface individually actuates each of the motion platforms by providing a client motion signal to each motion platform comprising the motion signal with a respective network address. Each motion platform is managed according to a respective feedback signal comprising the provided network address of each motion platform.

Abstract: The present invention relates to a method of treatment of movement disorders, comprising administering to a patient in need thereof an effective amount of befiradol, where in the administering step provides an average patient's maximum plasma concentration of befiradol below 15 ng/mL which occurs more than 4 hours post administration, said method minimizing side effects of dizziness and nausea. Sustained release pharmaceutical compositions that can be used according to this method are also described.

Abstract: A system for providing motion signals indicative of a motion to be performed by the motion platforms synchronously with video images comprising an input interface for extracting a motion signal from the input signal. A server provides a network address to each motion platform. A motion platform interface has control ports connected to arrays of motion platforms. Each motion platform being connected one to another by a wired connection according to a control protocol. The motion platform interface individually actuates each of the motion platforms by providing a client motion signal to each motion platform comprising the motion signal with a respective network address. Each motion platform is managed according to a respective feedback signal comprising the provided network address of each motion platform.

Abstract: Stable pharmaceutical composition consisting of a hydrosoluble vinflunine salt and at least one diluent and one lubricant, said composition being in the form of a solid intended for oral administration. The hydrosoluble vinflunine salt is preferably Vinflunine ditartrate. The pharmaceutical composition is advantageously in the form of a capsule or tablet. The invention also concerns a method of treating cancer pathology comprising the oral administration of the pharmaceutical composition of the invention.

Abstract: A system for providing motion signals indicative of a motion to be performed by the motion platforms synchronously with video images comprising an input interface for extracting a motion signal from the input signal. A server provides a network address to each motion platform. A motion platform interface has control ports connected to arrays of motion platforms. Each motion platform being connected one to another by a wired connection according to a control protocol. The motion platform interface individually actuates each of the motion platforms by providing a client motion signal to each motion platform comprising the motion signal with a respective network address. Each motion platform is managed according to a respective feedback signal comprising the provided network address of each motion platform.

Abstract: There is provided a system to provide a sequence of motion samples to a plurality of motion platforms, such as the plurality of seats in a movie theatre, such that the motion is synchronized with a sequence of images, such as a movie. In order to reduce the cost of the system, synchronization of a motion data signal with the sequence of images is centralized at a unique synchronizing unit. The synchronized sequence of motion samples is distributed to a plurality of motion platform hubs, each controlling and managing a reduced number of motion platforms.

Abstract: A method and a system for measuring amplitude and phase difference between two sinusoidal signals, using an adaptive filter. The method generally comprises measuring a sample of an output signal of a system excited by a sample of a reference signal; using an adaptive filter and the sample of the reference signal to determine a and b coefficients that minimize a prediction error on the sample of the output signal, iteratively, and determining the amplitude and/or phase of the output of the system using the a and b coefficients.

Abstract: There is described a method and device for encoding a vibro-kinetic signal (e.g., motion codes) directly onto a video player media (e.g., a DVD player) and for streaming the vibro-kinetic signal to a dedicated motion decoder in synchrony to the audio and video, while the movie support media (e.g., a DVD, a computer file, streaming data from a network) is being played. According to an embodiment, the multi-channel vibro-kinetic signal is encoded within one of the audio channels transported by the HDMI (High-Definition Multimedia Interface) link. Two methods are proposed to perform the encoding: Direct LSB (Least Significant Bit) Injection; and Perceptually Modulated Injection. There are also described corresponding decoding methods and motion decoders.

Abstract: There is described method for producing a computer file for inclusion in an audio bundle of a digital cinema file in which is encoded a multi-channel vibro-kinetic signal for controlling a motion platform. The audio bundle is for being transported over a digital transport link between a D-Cinema player and a motion decoder. The method comprises: obtaining a succession of blocks of vibro-kinetic samples from a vibro-kinetic file (e.g., a KineLink file); encoding binary data which represents the samples of the multi-channel vibro-kinetic signal into a sequence of monophonic PCM samples, according to a defined structure; and building a computer file using the encoded binary data, the computer file for incorporation into the audio bundle of the digital-cinema file, the encoded binary data for being transported over the digital transport link of the D-Cinema player to a motion decoder controlling the motion platform.

Abstract: The present description relates to the interfacing of a computer with a motion platform using a USB audio-class computer peripheral. The computer peripheral receives a digital audio-format signal according to the USB specification and provides a motion signal to up to four motion platforms. As the computer peripheral is a USB audio-class peripheral, no device-specific driver is required to play motion synchronously with a movie or a video game. The general purpose audio driver included in the operating system of the computer is advantageously used and the computer peripheral can alternately be used with any operating system comprising such a general purpose audio driver, such as Windows 2000, Windows XO or Mac OSX. The computer peripheral is seen by the computer as a USB sound card.

Abstract: A method and a system for measuring amplitude and phase difference between two sinusoidal signals, using an adaptive filter. The method generally comprises measuring a sample of an output signal of a system excited by a sample of a reference signal; using an adaptive filter and the sample of the reference signal to determine a and b coefficients that minimize a prediction error on the sample of the output signal, iteratively, and determining the amplitude and/or phase of the output of the system using the a and b coefficients.

Abstract: There is described method for producing a computer file for inclusion in an audio bundle of a digital cinema file in which is encoded a multi-channel vibro-kinetic signal for controlling a motion platform. The audio bundle is for being transported over a digital transport link between a D-Cinema player and a motion decoder. The method comprises: obtaining a succession of blocks of vibro-kinetic samples from a vibro-kinetic file (e.g., a KineLink file); encoding binary data which represents the samples of the multi-channel vibro-kinetic signal into a sequence of monophonic PCM samples, according to a defined structure; and building a computer file using the encoded binary data, the computer file for incorporation into the audio bundle of the digital-cinema file, the encoded binary data for being transported over the digital transport link of the D-Cinema player to a motion decoder controlling the motion platform.

Abstract: A system for providing motion signals indicative of a motion to be performed by the motion platforms synchronously with video images comprising an input interface for extracting a motion signal from the input signal. A server provides a network address to each motion platform. A motion platform interface has control ports connected to arrays of motion platforms. Each motion platform being connected one to another by a wired connection according to a control protocol. The motion platform interface individually actuates each of the motion platforms by providing a client motion signal to each motion platform comprising the motion signal with a respective network address. Each motion platform is managed according to a respective feedback signal comprising the provided network address of each motion platform.

Abstract: A stable pharmaceutical composition comprising a water-soluble vinorelbine salt and at least one diluent and one lubricant, characterized in that it appears in a solid form intended for oral administration. The water-soluble vinorelbine salt is advantageously vinorelbine ditartrate. The pharmaceutical composition advantageously appears as a gelatin capsule or tablet.

Abstract: Stable pharmaceutical composition consisting of a hydrosoluble vinflunine salt and at least one diluent and one lubricant, said composition being in the form of a solid intended for oral administration. The hydrosoluble vinflunine salt is preferably Vinflunine ditartrate. The pharmaceutical composition is advantageously in the form of a capsule or tablet. The invention also concerns a method of treating cancer pathology comprising the oral administration of the pharmaceutical composition of the invention.