Patents by Inventor Burkhard Jaeger

Burkhard Jaeger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of a potent HCV inhibitor
    Patent number: 8362035
    Abstract: This invention relates to novel crystalline forms of the following Compound (1), and the sodium salt thereof, and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: January 29, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thilo Berkenbusch, Carl Alan Busacca, Burkhard Jaeger, Richard J. Varsolona
  • CRYSTALLINE FORMS OF A POTENT HCV INHIBITOR
    Publication number: 20120270775
    Abstract: This invention relates to novel crystalline forms of the following Compound (1), and the sodium salt thereof, and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Application
    Filed: July 3, 2012
    Publication date: October 25, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Thilo BERKENBUSCH, Carl Alan BUSACCA, Burkhard JAEGER, Richard J. VARSOLONA
  • Crystalline forms of a potent HCV inhibitor
    Patent number: 8232293
    Abstract: This invention relates to novel crystalline forms of the following Compound (1), and the sodium salt thereof, and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: July 31, 2012
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thilo Berkenbusch, Carl Alan Busacca, Burkhard Jaeger, Richard J. Varsolona
  • Process for preparing aminocrotonylamino-substituted quinazoline derivatives
    Patent number: 8188274
    Abstract: The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: May 29, 2012
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Juergen Schroeder, Georg Dziewas, Thomas Fachinger, Burkhard Jaeger, Cartsen Reichel, Svenja Renner
  • Process for preparing aminocrotonylamino-substituted quinazoline derivatives
    Publication number: 20110207929
    Abstract: The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases.
    Type: Application
    Filed: May 5, 2011
    Publication date: August 25, 2011
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Juergen SCHROEDER, Georg DZIEWAS, Thomas FACHINGER, Burkhard JAEGER, Cartsen REICHEL, Svenja RENNER
  • Process for preparing aminocrotonylamino-substituted quinazoline derivatives
    Publication number: 20110207932
    Abstract: The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases.
    Type: Application
    Filed: May 5, 2011
    Publication date: August 25, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Juergen SCHROEDER, Georg DZIEWAS, Thomas FACHINGER, Burkhard JAEGER, Carsten REICHEL, Svenja RENNER
  • Process for preparing aminocrotonylamino-substituted quinazoline derivatives
    Patent number: 7960546
    Abstract: The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula (XIII) and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: June 14, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Juergen Schroeder, Georg Dziewas, Thomas Fachinger, Burkhard Jaeger, Carsten Reichel, Svenja Renner
  • CRYSTALLINE FORMS OF A POTENT HCV INHIBITOR
    Publication number: 20100093792
    Abstract: This invention relates to novel crystalline forms of the following Compound (1), and the sodium salt thereof, and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Application
    Filed: September 15, 2009
    Publication date: April 15, 2010
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thilo BERKENBUSCH, Carl Alan BUSACCA, Burkhard JAEGER, Richard J. VARSOLONA
  • PROCESS FOR PREPARING AMINOCROTONYLAMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES
    Publication number: 20090306378
    Abstract: The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula (XIII) and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases.
    Type: Application
    Filed: January 25, 2007
    Publication date: December 10, 2009
    Inventors: Juergen Schroeder, Georg Dziewas, Thomas Fachinger, Burkhard Jaeger, Carsten Reichel, Svenja Renner
  • Process for preparing optically active dihydropyrones
    Patent number: 7041845
    Abstract: The invention relates to a process for preparing optically active 5-hydroxy-3-ketoesters of formula A1 or A2, or one of the tautomers thereof, the use thereof for preparing optically active dihydropyrones of formula B, and the use of the dihydropyrones of formula B thus prepared as starting compounds for preparing pharmaceutically active compounds, particularly Tipranavir.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: May 9, 2006
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Burkhard Jaeger, Markus Sauter, Juergen Schroeder
  • Process for preparing optically active dihydropyrones
    Publication number: 20040133032
    Abstract: The invention relates to a process for preparing optically active 5-hydroxy-3-ketoesters of formula A1 or A2, 1
    Type: Application
    Filed: December 3, 2003
    Publication date: July 8, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Burkhard Jaeger, Markus Sauter, Juergen Schroeder
  • Process for preparing optically active dihydropyrones
    Patent number: 6500963
    Abstract: The invention relates to a new process for preparing optically active dihydropyrones, new intermediate products which may be obtained by this synthesis, and their use as starting compounds in the preparation of pharmaceutically active compounds.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: December 31, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Markus Sauter, Burkhard Jaeger
  • Process for preparing optically active dihydropyrones
    Publication number: 20020165269
    Abstract: The invention relates to a new process for preparing optically active dihydropyrones, new intermediate products which may be obtained by this synthesis, and their use as starting compounds in the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: February 14, 2002
    Publication date: November 7, 2002
    Inventors: Markus Sauter, Burkhard Jaeger