Abstract: The application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride or stannous pyrophosphate, potassium salts, and an amino acid (e.g., a basic amino acid) in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. Additionally, oral care compositions described here useful in order to naturally promote nitrate reduction from the oral microbiome, which can eventually result in systemic increases of nitric oxide in blood plasma, and can form part of an overall regimen to maintain or control blood pressure. Compositions comprise stannous fluoride, stannous chloride or stannous pyrophosphate, nitric acid or a water-soluble nitrate salt such as potassium nitrate, a water-soluble alkali metal polyphosphate such as tetrasodium pyrophosphate or trisodium polyphosphate, a basic amino aid such as arginine and more than 10 wt % water.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride, and/or stannous chloride, and/or stannous pyrophosphate and potassium salts, with a polyphosphate source, wherein the polyphosphate source comprises three or more phosphate moieties or units, in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous pyrophosphate and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor. The compositions comprise stannous pyrophosphate, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: Disclosed herein are oral compositions comprising an amino acid and a gelling agent. In certain embodiments, the chewable composition is in the form of a gummy comprising arginine and pectin. Related kits and methods of use are further provided.

Abstract: The disclosure relates to oral care compositions comprising guanidine in free or orally acceptable salt form and a stannous ion source (e.g., stannous fluoride) as well as to methods of using and of making these compositions.

Abstract: This application relates to novel black translucent oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a charcoal composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: In one aspect, the application relates to novel aqueous oral care compositions useful for combining and delivering potassium salts and a basic amino acid in a high-water composition, for example, to naturally promote nitrate reduction from the oral microbiome, which can result in systemic increases of nitric oxide in blood plasma and can form part of an overall regimen to maintain, reduce, treat or control systemic blood pressure.

Abstract: This application provides, among other things, novel aqueous monophasic compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.

Abstract: Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.

Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g., lysine, and methods for making and using the same.

Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g., lysine, and methods for making and using the same.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: This application provides, among other things, novel aqueous biphasic oral care compositions comprising two distinct aqueous phases, useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with short chain polyphosphate salts that protect against erosion and staining, by addition of a stabilizing amount of an anionic surfactant and methods for making and using the same.