Patents by Inventor Carl S. Brown
Carl S. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8848051Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines a virtual approximation plane or a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the virtual approximation plane or the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.Type: GrantFiled: February 11, 2010Date of Patent: September 30, 2014Assignees: Samsung Electronics, Co., Ltd., Applied Precision, Inc.Inventors: Kyu-sang Lee, Carl S. Brown, Kyla Teplitz, Steve Goodson
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Patent number: 8478069Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extent that respective contributions of the target object and each individual reflection may be distinguished and quantified.Type: GrantFiled: October 13, 2011Date of Patent: July 2, 2013Assignee: Applied Precision, Inc.Inventor: Carl S. Brown
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Patent number: 8333932Abstract: A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.Type: GrantFiled: February 11, 2010Date of Patent: December 18, 2012Assignees: Samsung Electronics Co., Ltd., Applied Precision, Inc.Inventors: Kyu-sang Lee, Seong-ho Cho, Carl S. Brown, Kyla Teplitz
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Patent number: 8115150Abstract: A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path.Type: GrantFiled: December 30, 2008Date of Patent: February 14, 2012Assignee: Applied Precision, Inc.Inventors: Carl S. Brown, Steven A. Reese
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Publication number: 20120033895Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extent that respective contributions of the target object and each individual reflection may be distinguished and quantified.Type: ApplicationFiled: October 13, 2011Publication date: February 9, 2012Applicant: APPLIED PRECISION, INC.Inventor: CARL S. BROWN
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Patent number: 8041146Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extend that respective contributions of the target object and each individual reflection may be distinguished and quantified.Type: GrantFiled: January 13, 2010Date of Patent: October 18, 2011Assignee: Applied Precision, IncInventor: Carl S. Brown
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Publication number: 20110117255Abstract: A method of preparing a blended alcoholic beverage and a blended alcoholic beverage formulation thus produced. The blended alcoholic beverage is made by a process including the steps of: a) combining a juiced fruit and optionally grinds of the juiced fruit with water and, optionally, other flavorings or additives, to produce a concentrate; b) blending the concentration with a sweetening agent; c) heating the sweetened concentrate for a period of time; d) filtering the heated concentrate; e) cooling the heated concentrate to a temperature between about 115 and 165° F.; 1) adding a proofed alcohol, and optionally a stabilizer, to the heated and cooled concentrate; and g) re-filtering the heated concentrate to produce the fruit-based alcoholic beverage.Type: ApplicationFiled: November 17, 2009Publication date: May 19, 2011Inventors: Carl S. Brown, Kevin P. Clang
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Publication number: 20100208061Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines one of a virtual approximation plane and a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the one of the virtual approximation plane and the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.Type: ApplicationFiled: February 11, 2010Publication date: August 19, 2010Applicants: SAMSUNG ELECTRONICS CO., LTD., APPLIED PRECISION, INC.Inventors: Kyu-sang LEE, Carl S. BROWN, Kyla TEPLITZ, Steve GOODSON
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Publication number: 20100210475Abstract: A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.Type: ApplicationFiled: February 11, 2010Publication date: August 19, 2010Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Kyu-sang LEE, Seong-ho CHO, Carl S. BROWN, Kyla TEPLITZ
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Publication number: 20100177984Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extend that respective contributions of the target object and each individual reflection may be distinguished and quantified.Type: ApplicationFiled: January 13, 2010Publication date: July 15, 2010Inventor: Carl S. Brown
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Patent number: 7683345Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.Type: GrantFiled: August 4, 2008Date of Patent: March 23, 2010Assignee: Applied Precision, Inc.Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
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Patent number: 7608840Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.Type: GrantFiled: August 4, 2008Date of Patent: October 27, 2009Assignee: Applied Precision, LLCInventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
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Publication number: 20090206238Abstract: A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path.Type: ApplicationFiled: December 30, 2008Publication date: August 20, 2009Applicant: Applied Precision, Inc. Delaware corporationInventors: Carl S. Brown, Steven A. Reese
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Publication number: 20090026386Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.Type: ApplicationFiled: August 4, 2008Publication date: January 29, 2009Applicant: Applied Precision, LLCInventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
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Publication number: 20090028413Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.Type: ApplicationFiled: August 4, 2008Publication date: January 29, 2009Applicant: Applied Precision, LLCInventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
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Publication number: 20080245953Abstract: An image acquisition system and method employing multi-axis integration (MAI) may incorporate both optical axis integration (OAI) and time-delay integration (TDI) techniques. Disclosed MAI systems and methods may integrate image data in the z direction as the data are acquired, projecting the image data prior to deconvolution. Lateral translation of the image plane during the scan in the z direction may allow large areas to be imaged in a single scan sequence.Type: ApplicationFiled: December 31, 2007Publication date: October 9, 2008Applicant: Applied Precision, LLCInventors: Steven A. REESE, Carl S. BROWN, Paul C. GOODWIN
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Patent number: 7408176Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.Type: GrantFiled: June 18, 2004Date of Patent: August 5, 2008Assignee: Applied Precision, LLCInventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
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Patent number: 7330588Abstract: Expression profiling using DNA microarrays is an important new method for analyzing cellular physiology. In “spotted” microarrays, fluorescently labeled cDNA from experimental and control cells is hybridized to arrayed target DNA and the arrays imaged at two or more wavelengths. Statistical analysis is performed on microarray images and show that non-additive background, high intensity fluctuations across spots, and fabrication artifacts interfere with the accurate determination of intensity information. The probability density distributions generated by pixel-by-pixel analysis of images can be used to measure the precision with which spot intensities are determined. Simple weighting schemes based on these probability distributions are effective in improving significantly the quality of microarray data as it accumulates in a multi-experiment database. Error estimates from image-based metrics should be one component in an explicitly probabilistic scheme for the analysis of DNA microarray data.Type: GrantFiled: September 23, 2004Date of Patent: February 12, 2008Assignee: Applied Precision, LLCInventors: Carl S. Brown, Paul C. Goodwin
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Patent number: 7283253Abstract: An image acquisition system and method employing multi-axis integration (MAI) may incorporate both optical axis integration (OAI) and time-delay integration (TDI) techniques. Disclosed MAI systems and methods may integrate image data in the z direction as the data are acquired, projecting the image data prior to deconvolution. Lateral translation of the image plane during the scan in the z direction may allow large areas to be imaged in a single scan sequence.Type: GrantFiled: March 13, 2003Date of Patent: October 16, 2007Assignee: Applied Precision, LLCInventors: Steven A. Reese, Carl S. Brown, Paul C. Goodwin
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Patent number: 7228003Abstract: A plurality of panels are assembled into a single image. Each of the panels may have different intensities throughout the panel, as well as non-uniformities between panels. The panels are modified using flat-field calibration, panel flattening, and panel connecting techniques. These techniques correct for non-uniformities and provide a cleaner, single image.Type: GrantFiled: June 18, 2004Date of Patent: June 5, 2007Assignee: Applied Precision, LLCInventor: Carl S. Brown