Patents by Inventor Carl S. Brown

Carl S. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8848051
    Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines a virtual approximation plane or a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the virtual approximation plane or the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: September 30, 2014
    Assignees: Samsung Electronics, Co., Ltd., Applied Precision, Inc.
    Inventors: Kyu-sang Lee, Carl S. Brown, Kyla Teplitz, Steve Goodson
  • Patent number: 8478069
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extent that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: July 2, 2013
    Assignee: Applied Precision, Inc.
    Inventor: Carl S. Brown
  • Patent number: 8333932
    Abstract: A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: December 18, 2012
    Assignees: Samsung Electronics Co., Ltd., Applied Precision, Inc.
    Inventors: Kyu-sang Lee, Seong-ho Cho, Carl S. Brown, Kyla Teplitz
  • Patent number: 8115150
    Abstract: A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: February 14, 2012
    Assignee: Applied Precision, Inc.
    Inventors: Carl S. Brown, Steven A. Reese
  • Publication number: 20120033895
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extent that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Application
    Filed: October 13, 2011
    Publication date: February 9, 2012
    Applicant: APPLIED PRECISION, INC.
    Inventor: CARL S. BROWN
  • Patent number: 8041146
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extend that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: October 18, 2011
    Assignee: Applied Precision, Inc
    Inventor: Carl S. Brown
  • Publication number: 20110117255
    Abstract: A method of preparing a blended alcoholic beverage and a blended alcoholic beverage formulation thus produced. The blended alcoholic beverage is made by a process including the steps of: a) combining a juiced fruit and optionally grinds of the juiced fruit with water and, optionally, other flavorings or additives, to produce a concentrate; b) blending the concentration with a sweetening agent; c) heating the sweetened concentrate for a period of time; d) filtering the heated concentrate; e) cooling the heated concentrate to a temperature between about 115 and 165° F.; 1) adding a proofed alcohol, and optionally a stabilizer, to the heated and cooled concentrate; and g) re-filtering the heated concentrate to produce the fruit-based alcoholic beverage.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 19, 2011
    Inventors: Carl S. Brown, Kevin P. Clang
  • Publication number: 20100208061
    Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines one of a virtual approximation plane and a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the one of the virtual approximation plane and the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.
    Type: Application
    Filed: February 11, 2010
    Publication date: August 19, 2010
    Applicants: SAMSUNG ELECTRONICS CO., LTD., APPLIED PRECISION, INC.
    Inventors: Kyu-sang LEE, Carl S. BROWN, Kyla TEPLITZ, Steve GOODSON
  • Publication number: 20100210475
    Abstract: A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.
    Type: Application
    Filed: February 11, 2010
    Publication date: August 19, 2010
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kyu-sang LEE, Seong-ho CHO, Carl S. BROWN, Kyla TEPLITZ
  • Publication number: 20100177984
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extend that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Application
    Filed: January 13, 2010
    Publication date: July 15, 2010
    Inventor: Carl S. Brown
  • Patent number: 7683345
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: March 23, 2010
    Assignee: Applied Precision, Inc.
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Patent number: 7608840
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: October 27, 2009
    Assignee: Applied Precision, LLC
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Publication number: 20090206238
    Abstract: A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path.
    Type: Application
    Filed: December 30, 2008
    Publication date: August 20, 2009
    Applicant: Applied Precision, Inc. Delaware corporation
    Inventors: Carl S. Brown, Steven A. Reese
  • Publication number: 20090026386
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Application
    Filed: August 4, 2008
    Publication date: January 29, 2009
    Applicant: Applied Precision, LLC
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Publication number: 20090028413
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Application
    Filed: August 4, 2008
    Publication date: January 29, 2009
    Applicant: Applied Precision, LLC
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Publication number: 20080245953
    Abstract: An image acquisition system and method employing multi-axis integration (MAI) may incorporate both optical axis integration (OAI) and time-delay integration (TDI) techniques. Disclosed MAI systems and methods may integrate image data in the z direction as the data are acquired, projecting the image data prior to deconvolution. Lateral translation of the image plane during the scan in the z direction may allow large areas to be imaged in a single scan sequence.
    Type: Application
    Filed: December 31, 2007
    Publication date: October 9, 2008
    Applicant: Applied Precision, LLC
    Inventors: Steven A. REESE, Carl S. BROWN, Paul C. GOODWIN
  • Patent number: 7408176
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 5, 2008
    Assignee: Applied Precision, LLC
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Patent number: 7330588
    Abstract: Expression profiling using DNA microarrays is an important new method for analyzing cellular physiology. In “spotted” microarrays, fluorescently labeled cDNA from experimental and control cells is hybridized to arrayed target DNA and the arrays imaged at two or more wavelengths. Statistical analysis is performed on microarray images and show that non-additive background, high intensity fluctuations across spots, and fabrication artifacts interfere with the accurate determination of intensity information. The probability density distributions generated by pixel-by-pixel analysis of images can be used to measure the precision with which spot intensities are determined. Simple weighting schemes based on these probability distributions are effective in improving significantly the quality of microarray data as it accumulates in a multi-experiment database. Error estimates from image-based metrics should be one component in an explicitly probabilistic scheme for the analysis of DNA microarray data.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: February 12, 2008
    Assignee: Applied Precision, LLC
    Inventors: Carl S. Brown, Paul C. Goodwin
  • Patent number: 7283253
    Abstract: An image acquisition system and method employing multi-axis integration (MAI) may incorporate both optical axis integration (OAI) and time-delay integration (TDI) techniques. Disclosed MAI systems and methods may integrate image data in the z direction as the data are acquired, projecting the image data prior to deconvolution. Lateral translation of the image plane during the scan in the z direction may allow large areas to be imaged in a single scan sequence.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: October 16, 2007
    Assignee: Applied Precision, LLC
    Inventors: Steven A. Reese, Carl S. Brown, Paul C. Goodwin
  • Patent number: 7228003
    Abstract: A plurality of panels are assembled into a single image. Each of the panels may have different intensities throughout the panel, as well as non-uniformities between panels. The panels are modified using flat-field calibration, panel flattening, and panel connecting techniques. These techniques correct for non-uniformities and provide a cleaner, single image.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: June 5, 2007
    Assignee: Applied Precision, LLC
    Inventor: Carl S. Brown