Abstract: The present invention relates to a device for a ventilated facade, comprising a plurality of panels (1) provided with at least two hooking elements (4), at least one upright profile (5) intended to be attached to a building, wherein the U-shaped upright profile (5), a hanger (10) for each hooking element (4) secured with the possibility of sliding and frontally to the upright profile (5), which is configured to hold the panel (1) and wherein the hanger (10) is provided with a central cavity (3), wherein the hooking element (4) is housed in the central cavity (3) in an assembly situation, enabling the hanger (10) to be frontally assembled to the upright profile (5) and access to the connecting element (26). Thus, it is possible to adjust the panels in height without the need for disassembly and at any stage of the installation, even after having finished their installation.

Abstract: A cylindrical lock with a latch bolt, including an electro-mechanical mechanism enabling pull-back of the latch bolt to a retracted position. In an exemplary embodiment, the electro-mechanical mechanism includes an electrically powered motor and a drive linkage system coupling the motor to the latch bolt, the electro-mechanical mechanism configured to fit within a cylindrical hole formed in a door.

Abstract: The present invention relates to a clamping device for ventilated facades comprising a plurality of panels (3) and at least two upper clamping features (9) for each panel (3), wherein the upper clamping features (9) comprise an upper main body (11) and a first flange (12) extending from the upper main body (11), wherein the first flange (12) is linkable to a lower edge (6) of a panel (3) of another adjacent row and is intended to be attached to the upright profile (1). The level of insulation of the facade against the entry of water from the outside into the insulation layer behind the panels is thus improved by allowing the use of panels that overlap their adjacent panels by means of double-fold flanges and that describe geometries that create areas for water collection and channeling.

Abstract: The present disclosure provides dry powder compositions of treprostinil prodrugs and methods of treating pulmonary hypertension (e.g., pulmonary arterial hypertension or PH associated with interstitial lung disease), in a patient in need thereof with the same. The dry powder composition includes (a) from about 0.5 wt % to about 5 wt % of a compound of Formula (I): a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, (b) from about 10 wt % to about 61 wt % of leucine, and the balance being (c) a sugar selected from the group consisting of trehalose and mannitol. The entirety of (a), (b), and (c) is 100 wt %, and R1 is tetradecyl, pentadecyl, hexadecyl, heptadecyl, or octadecyl. The method of treating PH includes administering an effective amount of the dry powder composition to the lungs of the patient by inhalation via a dry powder inhaler, during an administration period. In certain compositions and methods provided herein, R1 is hexadecyl, e.g., linear hexadecyl.

Abstract: Systems and methods described herein facilitate the management of personalized life information using a distributed ledger. For example, a distributed ledger system, such as one or more blockchains, may manage personalized life information of one or more individuals to, for example, determine an occurrence of a life event for a first individual based at least in part on personalized life information for the first individual, to access various types of personalized life information for the first individual in response to the determination of the occurrence of the life event for the first individual, and to provide a subset of the personalized life information data for the first individual to a user device associated with a second individual.

Abstract: In one aspect, the present disclosure provides a microRNA-33 (miR-33) inhibitor comprising a peptide nucleic acid covalently bound to a pH low insertion peptide. In another aspect, the present disclosure provides a method of treating pulmonary fibrosis in a subject, the method comprising administering to the subject a therapeutically effective amount of the miR-33 inhibitor. In some embodiments, the pulmonary fibrosis is idiopathic pulmonary fibrosis.

Abstract: Construction robot, for the construction of bridges, formed by a motorized chassis (4) and configured to run longitudinally along a beam (1) with a geo-positioning system (7) and one or more height-adjustable cutting tools (8) arranged over at least one edge of the beam (1). The cutting tools (8) vary the height according to the position of the robot.

Abstract: Embodiments disclosed herein may relate to systems and methods for secure authentication that enable a user to set up an account or log in an existing account upon an existing user vouching for the user. Embodiments disclosed herein relate to verifying one or more attributes of the user by transmitting multiple decentralized verification notifications to multiple existing users. Upon receiving a verification quorum, a request may be authenticated.

Abstract: Systems and methods are described to facilitate an efficient on-boarding experience for users joining a financial institution, while maintaining the integrity of certain operations to determine whether the users are eligible for certain financial products based on the personal information of the users. For instance, a first server may perform an approval process by receiving a request to verify an identity of the user using a digital identity service, sending to a second server a request to obtain one or more categories of personal information about the user, receiving personal information associated with the one or more categories selected by or authorized by the user, determining, based on at least some of the received personal information, that the user is approved for a payment card, and sending information associated with the payment card to a mobile device.

Abstract: Diffuser apparatus for turbine frames and outlet guide vanes are disclosed. An example diffuser is integrated into a turbine engine. The example diffuser includes a plurality of struts extending between an inner portion and an outer portion of the turbine engine; and a plurality of flowpath surfaces supported by the plurality of struts. The example plurality of flowpath surfaces extends circumferentially within the turbine engine at a plurality of radial spans to control diffusion of air flow within the turbine engine.

Abstract: The disclosure relates to a method for optimizing sample distribution in a laboratory system, the method comprising: retrieving, at a control unit of the laboratory system, one or more test requests for each sample provided to the laboratory system; controlling, by the control unit, a transport system of the laboratory system to convey the provided samples to one or more sample buffer units; creating, by the control unit, run instructions to run one or more requested tests on selected samples on a test plate based on optimization criteria; transmitting, by the control unit, the run instructions to an analyzer of the laboratory system; and controlling, by the control unit, the transport system to convey the selected samples for which one or more requested tests shall be executed from a sample buffer unit to the analyzer.

Abstract: A system for measurement of monochromatic attenuation for each wavelength of the spectrum, understood as such the attenuation at a wavelength of the spectrum with the spectral width provided by the measurement equipment, of the spectral attenuation in the spectral range of measurement, understood as such the set of monochromatic attenuations at all the wavelengths throughout the spectral range of measurement, and the total attenuation, understood as such the attenuation calculated by the integration of the spectral attenuation in the spectral range of measurement weighted with the solar spectrum.

Abstract: Provided is a computer-implemented process including obtaining a corpus of natural-language text documents, automatically generating questions about information in corresponding portions of the documents, and associating the questions with the corresponding portions of the documents. The process further includes storing the questions and the associations with the corresponding portions of the documents in memory to form an index of automatically-generated questions to corresponding portions of documents that answer the questions.

Abstract: Embodiments described herein disclose technology for verifying authorization of an application download. The system can receive from a device associated with a user, a request to download an application. In response to a first instance of the application being downloaded on the device, the system can assign a unique identifier to the first instance of the application. After the application is downloaded and prior to granting the person requesting the application download access to the first instance of the application, the system can request via the first instance of the application identification information and particular authentication information to verify that the person requesting the application download is authorized to do so. In response to verifying that the person requesting the application download is authorized, the unique identifier can be associated with the account, user and/or device to result in a verified download of the first instance of the application.

Abstract: Bridge construction method for a bridge formed by a series of beams placed between slabs, supported by angular profiles affixed to the beams. The method includes the steps of: fixing clips to edges of the upper surface of the beams, placing the beams on their supports, calculating the correct position of the angular profiles according to the shape or position of the beams; joining fasteners on the angular profiles, at an individual height determined according to the calculated positions; affixing the fasteners to the clips, so the angular profiles hang at the edges of the beams placing the slab on the angular profiles and casting concrete on the structure. The slabs are supported by angular profiles joined to the upper surface of the beams through a series of threaded protrusion carrying clips in said upper surface. Fasteners are joined to the clips and affixed to the angular profiles.

Abstract: The present disclosure relates to methods for treating bronchiectasis, for example, non-cystic fibrosis bronchiectasis with compositions comprising an effective amount of certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds of Formula (I), including pharmaceutically acceptable salts thereof, that inhibit dipeptidyl peptidase 1 (DPP1) activity. Methods provided herein are useful for prophylaxis, increasing the lung function in a patient, and/or and/or decreasing the rate of pulmonary exacerbation in a patient. In one embodiment, the compound of Formula (I) is (2S)—N-{(1S)-1-cyano-2-[4-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)phenyl]ethyl}-1,4-oxazepane-2-carboxamide.

Abstract: Provided is a process including obtaining a set of natural-language text documents that discuss a topic, the set of documents containing different states of knowledge about the topic at different times. The process includes selecting an ontology from among a plurality of ontologies that correspond to different domains of knowledge, the selection being based on the ontology corresponding to a domain of knowledge including the topic. The process includes identifying concepts discussed in the documents using the ontology and detecting changes in at least some of the concepts over time based on differences between discussion of the concepts in documents authored at different times. The process includes updating natural language instructions on the topic based on the detected changes in the concepts and storing the updated natural language instructions in memory.

Abstract: A system and a method for diagnosing a problem with a motor vehicle using sound. Ambient noise information for the motor vehicle is determined. Current sound information is received, and whether there is a variation in sound between the current sound information and the ambient noise information is determined. The ambient noise information is subtracted from the current sound information if the variation has been identified, to identify a sound anomaly. A sound anomaly signal is extracted and compared with predetermined anomaly signal information stored in a database. The predetermined anomaly signal information is associated with diagnostic information.

Abstract: The technology described herein detects a first device associated with a user that is within a detectable range of a second device. The system requests authentication information. In response to receiving the authentication information, a token generator associated with the user can generate a secure token. The secure token can be sent to the server. Once the secure token is verified, the user is granted access to one or more services.

Abstract: An authentication system may receive non-voice biometric authentication information from a user and authenticate the user via a first authentication method using the non-voice biometric authentication information. After authenticating the user via the first authentication method, the authentication system can enhance or create, based on a verbal request or a verbal command received from the user, a voice profile associated with the user. Once the profile is enhanced or created, the user is enrolled into a voice biometric authentication program.