Patents by Inventor Carlos Filipe

Carlos Filipe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240052312
    Abstract: The present disclosure relates to compositions, constructs and vectors for reprogramming cells into plasmacytoid dendritic cells or interferon type I-producing cells, methods and uses thereof. The present disclosure relates to the development of methods for making plasmacytoid dendritic cells or interferon type I-producing cells that promote antiviral and anti-tumoral immune responses from differentiated, multipotent or pluripotent stem cells by introducing and expressing isolated/synthetic transcription factors. More particularly, the disclosure provides methods for obtain plasmacytoid dendritic cells or interferon type I-producing cells by direct cellular reprogramming with the surprisingly use of combinations of specific transcription factors.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 15, 2024
    Inventors: Carlos Filipe Ribeiro Lemos Pereira, Cristiana Ferreira Pires, Fábio Fiúza Rosa, Abigail Altman
  • Publication number: 20240018200
    Abstract: The present disclosure relates to compositions, vectors, constructs, cells and methods for the reprogramming of cells into natural killer (NK) cells or progenitors. In particular, it relates to a combination of transcription factors for the reprogramming of cells.
    Type: Application
    Filed: December 17, 2021
    Publication date: January 18, 2024
    Inventors: Inês Maria Nascimento Caiado, Ilia Kurochkin, Gladys Telliam Dushime, Ewa Sitnicka Quinn, Carlos Filipe Ribeiro Lemos Pereira
  • Publication number: 20230306967
    Abstract: A computer implemented platform with the responsibility of handling complex tasks provided by users via a natural input interface (voice, text, image, among others). This platform design is based on the principle of full scalability, ambient and context awareness and with multi-domain extensible capability. The proposed computer-implemented system ensures the handling of input data provided by users via natural input interfaces, comprising a set of layers arranged in a modular and loosely coupled architecture, wherein the set of layers are adapted to interpret and manage several types of contextual information from the user input data, while permanently improving decisioning and response times, enabling increasingly complex interactions with the user.
    Type: Application
    Filed: May 30, 2022
    Publication date: September 28, 2023
    Inventors: Carlos Filipe LOPES TORRAO, Carolina Pimentel FERNANDES MAIO, Bruno SOUSA ROSA CRUZ FERNANDES, Joao Miguel NUNES FERREIRA, Jorge Filipe PINTO SEQUEIRA DOS SANTOS GRACA
  • Patent number: 11692215
    Abstract: This disclosure relates to biosensors, and in particular, biosensors based on nucleic acid cleaving enzymes such as ribonucleotide-cleaving DNAzymes for the detection of analytes, and methods of use.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: July 4, 2023
    Assignee: McMaster University
    Inventors: Carlos Filipe, Yingfu Li, Sahar Esmaeili Samani, Dingran Chang, Erin M. McConnell, Meghan Rothenbroker
  • Publication number: 20230144557
    Abstract: A method of preserving one or more chemical and/or biological species in a polymer matrix comprising pullulan and trehalose is described. The method includes combining the one or more chemical and/or biological species, an aqueous pullulan and a trehalose solution and drying the resultant mixture to provide a solid polymeric matrix in the form of a powder and/or with a water content of less than 10 wt %. The polymeric matrix comprising the one or more chemical and/or biological species and its use, for example, in biological preparations and medicaments is also described.
    Type: Application
    Filed: April 13, 2021
    Publication date: May 11, 2023
    Inventors: Vincent Ho Yin Leung, Sana Jahanshahi-Anbuhi, Carlos Filipe, M. Monsur Ali
  • Patent number: 11549945
    Abstract: Provided herein are nucleic acid-cleaving catalytic nucleic acid probes, biosensors and lateral flow biosensor devices and methods and kits of using the probes, biosensors and lateral flow biosensor devices for detecting an analyte present on or generated from a microorganism in a test sample, including Helicobacter pylori and methods for determining whether a subject has a Helicobacter pylori infection.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: January 10, 2023
    Assignee: McMaster University
    Inventors: John D. Brennan, Yingfu Li, Monsur Ali, Carlos Filipe, Michael Gregory Wolfe
  • Publication number: 20220325244
    Abstract: The present disclosure relates to compositions, nucleic acid constructs, methods and kits thereof for cell induction or reprogramming cells to the dendritic cell state or antigen presenting cell state, based, in part, on the surprisingly effect described herein of novel use and combinations of transcription factors that permit induction or reprogramming of differentiated or undifferentiated cells into dendritic cells or antigen presenting cells. Such compositions, nucleic acid constructs, methods and kits can be used for inducing dendritic cells in vitro, ex vivo, or in vivo, and these induced dendritic cells or antigen presenting cells can be used for immunotherapy applications.
    Type: Application
    Filed: April 26, 2022
    Publication date: October 13, 2022
    Inventors: Carlos Filipe Ribeiro Lemos Pereira, Cristiana Ferreira Pires, Fábio Alexandre Fiúza Rosa
  • Patent number: 11345891
    Abstract: The present disclosure relates to compositions, nucleic acid constructs, methods and kits thereof for cell induction or reprogramming cells to the dendritic cell state or antigen presenting cell state, based, in part, on the surprisingly effect described herein of novel use and combinations of transcription factors that permit induction or reprogramming of differentiated or undifferentiated cells into dendritic cells or antigen presenting cells. Such compositions, nucleic acid constructs, methods and kits can be used for inducing dendritic cells in vitro, ex vivo, or in vivo, and these induced dendritic cells or antigen presenting cells can be used for immunotherapy applications.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: May 31, 2022
    Assignee: Asgard Therapeutics AB
    Inventors: Carlos Filipe Ribeiro Lemos Pereira, Cristiana Ferreira Pires, Fabio Alexandre Fiuza Rosa
  • Publication number: 20220065851
    Abstract: The present application is directed to methods of performing chemical reactions, including multi-step chemical reactions in which two or more of the reagents in the chemical reaction are incorporated or entrapped in a solid polymeric structure comprising pullulan. In certain embodiments, the chemical reaction or multi-step reaction serves as a sensor. Accordingly the present application is also directed to sensors for performing the methods of the application. In certain embodiments, at least one of the reagents is a biomolecule and the sensor is a biosensor. In certain other embodiments, the solid polymeric structure comprising pullulan and the reagents for performing a chemical reaction form a convenient device for performing a chemical reaction.
    Type: Application
    Filed: June 28, 2021
    Publication date: March 3, 2022
    Applicant: McMaster University
    Inventors: Carlos Filipe, John D. Brennan, Robert Pelton, Sana Jahanshahi-Anbuhi, Yingfu Li
  • Publication number: 20210283065
    Abstract: A method of preserving the one or more chemical and/or biological species in a polymer matrix comprising pullulan and trehalose is described. The method includes combining the one or more chemical and/or biological species, an aqueous pullulan and a trehalose solution and drying the resultant mixture to provide a solid polymeric matrix. A polymeric matrix comprising one or more chemical and/or biological species and its use, for example, on surfaces for food preparation, for food preservation and in biological preparations is also described.
    Type: Application
    Filed: June 3, 2021
    Publication date: September 16, 2021
    Applicant: McMaster University
    Inventors: Vincent Ho Yin Leung, Sana Jahanshahi-Anbuhi, Carlos Filipe, M.Monsur Ali
  • Publication number: 20210262013
    Abstract: This disclosure relates to biosensors, and in particular, biosensors based on nucleic acid cleaving enzymes such as ribonucleotide-cleaving DNAzymes for the detection of analytes, and methods of use.
    Type: Application
    Filed: February 19, 2021
    Publication date: August 26, 2021
    Inventors: Carlos Filipe, Yingfu Li, Sahar Esmaeili Samani, Dingran Chang, Erin M. McConnell, Meghan Rothenbroker
  • Patent number: 11067569
    Abstract: The present application is directed to methods of performing chemical reactions, including multi-step chemical reactions in which two or more of the reagents in the chemical reaction are incorporated or entrapped in a solid polymeric structure comprising pullulan. In certain embodiments, the chemical reaction or multi-step reaction serves as a sensor. Accordingly the present application is also directed to sensors for performing the methods of the application. In certain embodiments, at least one of the reagents is a biomolecule and the sensor is a biosensor. In certain other embodiments, the solid polymeric structure comprising pullulan and the reagents for performing a chemical reaction form a convenient device for performing a chemical reaction.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: July 20, 2021
    Assignee: MCMASTER UNIVERSITY
    Inventors: Carlos Filipe, John D. Brennan, Robert Pelton, Sana Jahanshahi-Anbuhi, Yingfu Li
  • Patent number: 11040015
    Abstract: A method of preserving the one or more chemical and/or biological species in a polymer matrix comprising pullulan and trehalose is described. The method includes combining the one or more chemical and/or biological species, an aqueous pullulan and a trehalose solution and drying the resultant mixture to provide a solid polymeric matrix. A polymeric matrix comprising one or more chemical and/or biological species and its use, for example, on surfaces for food preparation, for food preservation and in biological preparations is also described.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: June 22, 2021
    Assignee: McMaster University
    Inventors: Vincent Ho Yin Leung, Sana Jahanshahi- Anbuhi, Carlos Filipe, M. Monsur Ali
  • Publication number: 20200363413
    Abstract: Provided herein are nucleic acid-cleaving catalytic nucleic acid probes, biosensors and lateral flow biosensor devices and methods and kits of using the probes, biosensors and lateral flow biosensor devices for detecting an analyte present on or generated from a microorganism in a test sample, including Helicobacter pylori and methods for determining whether a subject has a Helicobacter pylori infection.
    Type: Application
    Filed: May 15, 2020
    Publication date: November 19, 2020
    Inventors: John D. Brennan, Yingfu Li, Monsur Ali, Carlos Filipe, Michael Gregory Wolfe
  • Patent number: 10711918
    Abstract: A deflector (38) including: a support (70); an intermediate member (72), pivotally mounted in the support (70) around a first rotation axis (B-B?); at least a secondary pivoting member (74), pivotally connected to the intermediate member (72) around a second rotation axis (C-C?) parallel to the first rotation axis (B-B?); for each secondary pivoting member (74), at least a pair of rotating members (76). Each rotating member (76) is connected to the secondary pivoting member (74). The deflector (38) including: a guiding mechanism, for guiding each rotating member (76) in translation with regard to the support (70) along a translation axis (D-D?) non parallel to the first rotation axis (B-B?); a connecting member (78), pivotally mounted to the secondary pivoting member (74). The rotating member (76) is rotatably mounted on the connecting member (78) around a rotating member rotation axis (E-E?).
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: July 14, 2020
    Assignee: TECHNIP FRANCE
    Inventors: Mário Augusto Lopes De Castro, Jucimar Coelho Moza, Leonardo-Alexandre Lucena, Carolina-Paiva Nascimento, José-Roberto Correa, Paula Duarte, Paulo-Webber Gil, Luis Paulo Ferreira, Carlos-Filipe Santos
  • Patent number: 10653139
    Abstract: The present disclosure relates to a method for protecting stored agricultural dry products during storage, consisting of a controlled release system of essential oils and a shell for allowing oil diffusion in vapour phase towards the outer atmosphere without direct contact of the support material with stored products. This system is characterized by being suitable for use within containers for protecting stored dried agricultural plant products for a long period of time, in particular more than 4 weeks, more preferably more than 8 or 12 weeks.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 19, 2020
    Assignees: UNIVERSIDADE DO PORTO, INSTITUTO SUPERIOR DE AGRONOMIA, INSTITUTO NACIONAL DE INVESTIGAÇÃO AGRÁRIA E VETERINÁRIA
    Inventors: Margarida Maria Da Silva Monteiro Bastos, Fernão Domingos De Montenegro Baptista Malheiro De Magalhaes, José Manuel Ribeiro De Sousa, Carlos Filipe Gonçalves Pires Da Silva, Joana Vieira De Freitas Barbosa, António Maria Marques Mexia, Ana Maria Da Costa Aldir Magro, Maria Da Graça Fraga Freire De Barros Barbosa Maia, Cláudia Verónica Sánchez Lara, José Manuel Ferreira Nobre Semedo, Maria Manuela Roldão De Oliveira, Olivia Cruz De Matos
  • Publication number: 20200017832
    Abstract: The present disclosure relates to compositions, nucleic acid constructs, methods and kits thereof for cell induction or reprogramming cells to the dendritic cell state or antigen presenting cell state, based, in part, on the surprisingly effect described herein of novel use and combinations of transcription factors that permit induction or reprogramming of differentiated or undifferentiated cells into dendritic cells or antigen presenting cells. Such compositions, nucleic acid constructs, methods and kits can be used for inducing dendritic cells in vitro, ex vivo, or in vivo, and these induced dendritic cells or antigen presenting cells can be used for immunotherapy applications.
    Type: Application
    Filed: April 5, 2018
    Publication date: January 16, 2020
    Inventors: Carlos Filipe Ribeiro Lemos Pereira, Cristiana Ferreira Pires, Fábio Alexandre Fiúza Rosa
  • Publication number: 20190211946
    Abstract: A deflector (38) including: a support (70); an intermediate member (72), pivotally mounted in the support (70) around a first rotation axis (B-B?); at least a secondary pivoting member (74), pivotally connected to the intermediate member (72) around a second rotation axis (C-C?) parallel to the first rotation axis (B-B?); for each secondary pivoting member (74), at least a pair of rotating members (76). Each rotating member (76) is connected to the secondary pivoting member (74). The deflector (38) including: a guiding mechanism, for guiding each rotating member (76) in translation with regard to the support (70) along a translation axis (D-D?) non parallel to the first rotation axis (B-B?); a connecting member (78), pivotally mounted to the secondary pivoting member (74). The rotating member (76) is rotatably mounted on the connecting member (78) around a rotating member rotation axis (E-E?).
    Type: Application
    Filed: September 8, 2017
    Publication date: July 11, 2019
    Inventors: Mário Augusto LOPES DE CASTRO, Jucimar Coelho MOZA, Leonardo-Alexandre LUCENA, Carolina-Paiva NASCIMENTO, José-Roberto CORREA, Paula DUARTE, Paulo-Webber GIL, Luis Paulo FERREIRA, Carlos-Filipe SANTOS
  • Publication number: 20190178880
    Abstract: The present application is directed to methods of performing chemical reactions, including multi-step chemical reactions in which two or more of the reagents in the chemical reaction are incorporated or entrapped in a solid polymeric structure comprising pullulan. In certain embodiments, the chemical reaction or multi-step reaction serves as a sensor. Accordingly the present application is also directed to sensors for performing the methods of the application. In certain embodiments, at least one of the reagents is a biomolecule and the sensor is a biosensor. In certain other embodiments, the solid polymeric structure comprising pullulan and the reagents for performing a chemical reaction form a convenient device for performing a chemical reaction.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 13, 2019
    Applicant: McMaster University
    Inventors: Carlos Filipe, John D. Brennan, Robert Pelton, Sana Jahanshahi-Anbuhi, Yingfu Li
  • Publication number: 20190111006
    Abstract: A method of preserving the one or more chemical and/or biological species in a polymer matrix comprising pullulan and trehalose is described. The method includes combining the one or more chemical and/or biological species, an aqueous pullulan and a trehalose solution and drying the resultant mixture to provide a solid polymeric matrix. A polymeric matrix comprising one or more chemical and/or biological species and its use, for example, on surfaces for food preparation, for food preservation and in biological preparations is also described.
    Type: Application
    Filed: October 16, 2018
    Publication date: April 18, 2019
    Applicant: McMaster University
    Inventors: Vincent Ho Yin Leung, Sana Jahanshahi- Anbuhi, Carlos Filipe, M. Monsur Ali