Patents by Inventor Carlos Guillermo Borroto Nordelo

Carlos Guillermo Borroto Nordelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10104889
    Abstract: The present invention describes a method for the stimulation of the natural defense and the induction of resistance to diseases in plants by simultaneous activation of genes related to the route of the salicylic acid, the jasmonic acid/ethylene and the hypersensitive response. The invention also includes the use of brassinosteroids for the preventive and curative treatment against plant diseases caused by pathogens. In addition, includes a method for the prevention and treatment of the Huanglongbing disease in citrus.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: October 23, 2018
    Assignee: Centro de Ingeniería Genética y Biotechnología
    Inventors: Orlando Borrás Hidalgo, Eduardo Canales López, Merardo Pujol Ferrer, Carlos Guillermo Borroto Nordelo, Yamilet Coll García
  • Patent number: 9055744
    Abstract: The present invention reveals a nucleic acid sequence from Nicotiana megalosiphon encoding for an anti-pathogenic protein. The invention comprises the use of this nucleic acid molecule in transgenic plants of agricultural interest to confer resistance to pathogens. The invention also includes a bioproduct that comprises this anti-pathogenic protein to control plant pathogen agents.
    Type: Grant
    Filed: April 18, 2013
    Date of Patent: June 16, 2015
    Assignee: Centro de Ingenieria Genetica y Biotecnologia
    Inventors: Orlando Borras Hidalgo, Roxana Caridad Portieles Alvarez, Merardo Pujol Ferrer, Gil Alberto Enriquez Obregon, Ernesto Manuel Gonzalez Ramos, Camilo Ayra Pardo, Carlos Guillermo Borroto Nordelo
  • Publication number: 20140171326
    Abstract: The present invention describes a method for the stimulation of the natural defense and the induction of resistance to diseases in plants by simultaneous activation of genes related to the route of the salicylic acid, the jasmonic acid/ethylene and the hypersensitive response. The invention also includes the use of brassinosteroids for the preventive and curative treatment against plant diseases caused by pathogens. In addition, includes a method for the prevention and treatment of the Huanglongbing disease in citrus.
    Type: Application
    Filed: February 27, 2012
    Publication date: June 19, 2014
    Inventors: Orlando Borras Hidalgo, Eduardo Canales López, Merardo Pujol Ferrer, Carlos Guillermo Borroto Nordelo, Yamilet Coll Garcia
  • Patent number: 8450559
    Abstract: The present invention reveals a nucleic acid sequence from Nicotiana megalosiphon encoding for an anti-pathogenic protein. The invention comprises the use of this nucleic acid molecule in transgenic plants of agricultural interest to confer resistance to pathogens. The invention also includes a bioproduct that comprises this anti-pathogenic protein to control plant pathogen agents.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: May 28, 2013
    Assignee: Centro de Ingenieria Genetica y Biotecnologia
    Inventors: Orlando Borrás Hidalgo, Roxana Caridad Portieles Álvarez, Merardo Pujol Ferrer, Gil Alberto Enriquez Obregón, Ernesto Manuel González Ramos, Camilo Ayra Pardo, Carlos Guillermo Borroto Nordelo
  • Patent number: 8409562
    Abstract: The current invention describes chimeric vaccine antigens against the virus that causes the Classic Swine Fever (CSFV). Such vaccine antigens are based on viral subunits coupled to proteins able to stimulate cellular and humoral immune system. Chimeric antigens can be produced in expression systems that guarantee a correct tertiary structure folding of the chimeric molecules, which constitute the essence of the current invention. The vaccine formulations containing such chimeric antigens induce an early and potent immune response on vaccinated pigs and confer full protection against CSFV. Moreover, the resultant vaccine formulations prevent the viral transmission from sows to their offspring. The chimeric antigens, as well as the resultant vaccine formulations, can be applied in animal health as vaccines for preventive use in swine.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: April 2, 2013
    Assignees: Centro de Ingenieria Genetica y Biotecnologia, Centro Nacional de Sanidad Agropecuaria
    Inventors: Jorge Roberto Toledo Alonso, Oliberto Sánchez Ramos, Maritza Isidra Barrera Valle, Nancy Elena Figueroa Baile, Yanet Prieto Carratala, Maria Pilar Rodriguez Molto, Maria Teresa Frias Lepoureau, Carlos Guillermo Borroto Nordelo
  • Publication number: 20110124581
    Abstract: The present invention reveals a nucleic acid sequence from Nicotiana megalosiphon encoding for an anti-pathogenic protein. The invention comprises the use of this nucleic acid molecule in transgenic plants of agricultural interest to confer resistance to pathogens. The invention also includes a bioproduct that comprises this anti-pathogenic protein to control plant pathogen agents.
    Type: Application
    Filed: March 27, 2009
    Publication date: May 26, 2011
    Inventors: Orlando Borrás Hidalgo, Roxana Caridad Portieles Álvarez, Merardo Pujol Ferrer, Gil Alberto Enriquez Obregón, Ernesto Manuel González Ramos, Camilo Ayra Pardo, Carlos Guillermo Borroto Nordelo
  • Publication number: 20100300166
    Abstract: A composition to stimulate the development and growth of plants that comprises at least a Tsukamurella paurometabola strain, biofertilizing agent that optimize the assimilation of the organic matter by plants, favoring the intake of nitrogen and phosphorus by the plant.
    Type: Application
    Filed: April 29, 2008
    Publication date: December 2, 2010
    Inventors: Jesús Mena Campos, Eulogio Pimentel Vázquez, Marieta Marín Bruzos, Armando Tomás Hernández García, Ileana Sánchez Ortiz, Yamilka Ramírez Núñez, Sonia González Blanco, Marianela García Siverio, Carlos Guillermo Borroto Nordelo
  • Publication number: 20090324644
    Abstract: The present invention describes chimeric vaccine antigens against the avian influenza virus (AIV). Said vaccine antigens are based on viral subunits that are coupled to protein molecules that stimulate not only the cellular but also the humoral immune system. The chimeric antigens may be produced in expression systems that guarantee correct three-dimensional folding of the chimeric molecules that constitute the basis of the present invention. The vaccine compositions that contain said chimeric antigens induce a potent, early immune response both in birds and in vaccinated mammals, stimulating high haemagglutinin-inhibiting antibody titres and a potent specific cellular response against the viral antigen. The chimeric antigens, and also the resulting vaccine compositions, are applicable to the field of human and animal health as vaccines for preventive use.
    Type: Application
    Filed: February 28, 2007
    Publication date: December 31, 2009
    Inventors: Oliberto Sanchez Ramos, Jorge Roberto Toledo Alonso, Damarys Diaz Archer, Nancy Elena Figueroa Baile, Maria Pilar Rodriguez Molto, Carlos Guillermo Borroto Nordelo
  • Publication number: 20090304633
    Abstract: The current invention describes chimeric vaccine antigens against the virus that causes the Classic Swine Fever (CSFV). Such vaccine antigens are based on viral subunits coupled to proteins able to stimulate cellular and humoral immune system. Chimeric antigens can be produced in expression systems that guarantee a correct tertiary structure folding of the chimeric molecules, which constitute the essence of the current invention. The vaccine formulations containing such chimeric antigens induce an early and potent immune response on vaccinated pigs and confer full protection against CSFV. Moreover, the resultant vaccine formulations prevent the viral transmission from sows to their offspring. The chimeric antigens, as well as the resultant vaccine formulations, can be applied in animal health as vaccines for preventive use in swine.
    Type: Application
    Filed: February 28, 2007
    Publication date: December 10, 2009
    Applicants: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA, CENTRO NACIONAL DE SANIDAD AGROPECUARIA
    Inventors: Jorge Roberto Toledo Alonso, Oliberto Sánchez Ramos, Maritza Isidra Barrera Valle, Nancy Elena Figueroa Baile, Yanet Prieto Carratala, Maria Pilar Rodriguez Molto, Maria Teresa Frias Lepoureau, Carlos Guillermo Borroto Nordelo