Patents by Inventor Carmen Piunno

Carmen Piunno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6194136
    Abstract: This invention relates to methods, apparatus and solutions for cryopreserving microscopic biological materials for biologically extended periods of time. The method comprises treating a suspension of biological material, in an appropriate buffer, with a cryoprotectant or combination of cryoprotectants which raises the glass transition temperature range of the sample. One or more dry protectants may be added to the cryosolution. The cryosolution is then nebulized and rapidly cooled with novel apparatus, dried by molecular distillation, stored and then rehydrated in a buffer prior to its use. The solutions comprise novel mixtures of cryoprotectants.
    Type: Grant
    Filed: July 13, 1998
    Date of Patent: February 27, 2001
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Carmen Piunno, David P. Ross
  • Patent number: 5780295
    Abstract: This invention relates to methods, apparatus and solutions for cryopreserving microscopic biological materials for biologically extended periods of time. The method comprises treating a suspension of biological material, in an appropriate buffer, with a cryoprotectant or combination of cryoprotectants which raises the glass transition temperature range of the sample. One or more dry protectants may be added to the cryosolution. The cryosolution is then nebulized and rapidly cooled with novel apparatus, dried by molecular distillation, stored and then rehydrated in a buffer prior to its use. The solutions comprise novel mixtures of cryoprotectants.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: July 14, 1998
    Assignee: Life Cell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Carmen Piunno, David P. Ross
  • Patent number: 5154007
    Abstract: This invention relates to an apparatus and method for distillation drying of one or more biological samples. The drying apparatus includes a retaining assembly, a vacuum assembly, cooling means, monitoring means and control means for actively regulating the temperature and pressure conditions of biological tissue so that such tissue may be dried without substantial ultrastructural damage.
    Type: Grant
    Filed: March 13, 1990
    Date of Patent: October 13, 1992
    Assignee: Board of Regents University of Texas System
    Inventors: Carmen Piunno, Stephen Livesey, John G. Linner, Anthony A. del Campo, Mark J. Zaltzberg
  • Patent number: 5044165
    Abstract: A method and apparatus for ultrarapid cooling of tissue samples against a chilled cryogenic surface. The cryogenic surface is enclosed in a high vacuum chamber during cooling of the cryogenic surface. Dry non-condensable room temperature gas is introduced from an external source to raise the chamber pressure just prior to slamming or plunging a sample against the cryogenic surface. The cryogenic surface is heated for regeneration or cleaning purposes between each successive sample.
    Type: Grant
    Filed: December 15, 1988
    Date of Patent: September 3, 1991
    Assignee: Board of Regents, The University of Texas
    Inventors: John G. Linner, Stephen A. Livesey, Carmen Piunno, Mark Zaltsberg, Frank Gibson
  • Patent number: 4964280
    Abstract: This invention relates to an apparatus and method for distillation drying of one or more biological samples. The drying apparatus includes a retaining assembly, a vacuum assembly, cooling means, monitoring means and control means for actively regulating the temperature and pressure conditions of biological tissue so that such tissue may be dried without substantial ultrastructural damage.
    Type: Grant
    Filed: August 17, 1989
    Date of Patent: October 23, 1990
    Assignee: Board of Regents
    Inventors: Carmen Piunno, Stephen Livesey, John G. Linner, Anthony A. del Campo, Mark J. Zaltzberg