Patents by Inventor Carmine P. Iovine
Carmine P. Iovine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9511147Abstract: This invention relates to compositions and applications for an mterpolymer network delivery system containing iodine.Type: GrantFiled: August 12, 2012Date of Patent: December 6, 2016Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Joachim B. Kohn, Carmine P. Iovine, Niraj Ramachandran
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Publication number: 20140308331Abstract: This invention relates to compositions and applications for an interpolymer network delivery system containing iodine.Type: ApplicationFiled: August 12, 2012Publication date: October 16, 2014Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Joachim B. Kohn, Carmine P. Iovine, Niraj Ramachandran
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Patent number: 8367110Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: GrantFiled: April 5, 2012Date of Patent: February 5, 2013Assignee: Rutgers, The State University of New JerseyInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Publication number: 20120207796Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: ApplicationFiled: April 5, 2012Publication date: August 16, 2012Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Publication number: 20090238858Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: ApplicationFiled: February 20, 2009Publication date: September 24, 2009Applicant: Rutgers, The State University of New JerseyInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Patent number: 5656367Abstract: A biodegradable binder for nonwoven stock is prepared as an emulsion of 5-200% solids of poly(hydroxybutyrate/hydroxyvalerate) copolymer in water in which the copolymer comprises 70-100 mole percent of 3-hydroxybutyrate and 0-30 percent of 3-hydroxyvalerate.Type: GrantFiled: April 29, 1994Date of Patent: August 12, 1997Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, John H. Walton
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Patent number: 5346974Abstract: This invention provides polyether polycarboxylate compositions selected from the group consisting of polyether polycarboxylates which may be prepared by oxidizing copolymers of furan and maleic anhydride, and other polyether polycarboxylate compositions prepared by oxidizing novel, intermediate polymers of furan, maleic anhydride, and at least one copolymerizable comonomer, selected from the group consisting of furan, alkenyl alkyl ethers, alkyl acrylates, alkenyl carboxyalkyl ethers, vinyl esters of carboxylic acids, unsaturated carboxylic acids, unsaturated dicarboxylic acids and their anhydrides and esters, and olefins. This invention also provides novel, unoxidized terpolymer intermediates comprising furan, maleic anhydride, and at least one copolymerizable comonomer, other than furan and maleic anhydride, selected from the above group, as well as a process for oxidizing these polymers and the furan and maleic anhydride copolymers.Type: GrantFiled: September 17, 1992Date of Patent: September 13, 1994Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, Rama S. Chandran, John C. Leighton
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Patent number: 5312850Abstract: Hot melt adhesive compositions are prepared from 20 to 98% by weight of a polylactide homo- or copolymer containing at least 20 molar percent of the lactide component; 2 to 80% by weight of a polar tackifier having a Ring and Ball softening point (as described by ASTM E-26) greater than about 60.degree. C.; 0 to 50% by weight of a plasticizer; 0 to 30% by weight of a wax diluent; 0-3% by weight of a stabilizer; and 0-20% of starch. By utilizing a naturally occurring, thermoplastic, biodegradable copolymer as the base polymer, these adhesives advance the state of the art of hot melt adhesives by alleviating the dependence on petroleum based materials and by allowing for the development of hot melt adhesives which either degrade naturally after coming in contact with the soil or which can be composted.Type: GrantFiled: January 4, 1993Date of Patent: May 17, 1994Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, Thomas F. Kauffman, Jules E. Schoenberg, Paul P. Puletti
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Patent number: 5308530Abstract: This invention provides detergent compositions, particularly liquid compositions, utilizing one or more polycarboxylates as builders, or as anti-redeposition agents, wherein the polycarboxylates are novel polymers comprising repeating units of the structure: ##STR1## wherein m is a mole fraction from 0.70 to 0.95; n is a mole fraction from 0.05 to 0.30; A is derived from at least one ethylenically unsaturated carboxylic acid monomer; B is derived from at least one ethylenically unsaturated carboxylic acid monomer and B is not A; and C is: ##STR2## wherein X is --H, ##STR3## or a combination thereof, R.sup.1 is --H, --CH.sub.3, or --(CH.sub.2).sub.q CH.sub.3, or a combination thereof, and q is 1-5; R.sup.2 is: ##STR4## or R.sup.3 , or a combination thereof, and R.sup.3 is a C.sub.8 -C.sub.18 linear or branched alkyl chain; the interpolymer being prepared by polymerizing the monomers in a solvent system in which the monomers and interpolymer are soluble.Type: GrantFiled: November 21, 1990Date of Patent: May 3, 1994Assignee: Lever Brothers Company, Division of Conopco, Inc.Inventors: Michael P. Aronson, Ingrid Brase, David L. Elliott, John F. Hessel, Carmine P. Iovine, John C. Leighton, J. Thomas McCown
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Patent number: 5278211Abstract: Formaldehyde free crosslinking emulsion polymers are prepared by the addition of N-(2,2-dialkoxy-1-hydroxy)ethyl acrylamide to a vinyl ester based polymer. The resultant emulsions can be used as binders for nonwovens or fiberfill or as woodworking adhesives.Type: GrantFiled: April 5, 1993Date of Patent: January 11, 1994Assignee: National Starch and Chemical Investment Holding CorporationInventors: Rama S. Chandran, Carmine P. Iovine, Paul R. Mudge, John C. Leighton, Pravin K. Kukkala
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Patent number: 5252663Abstract: Formaldehyde free crosslinking emulsion polymers are prepared by the addition of N-(2,2-dialkoxy-1-hydroxy)ethyl acrylamide to a vinyl ester based polymer. The resultant emulsions can be used as binders for nonwovens or fiberfill or as woodworking adhesives.Type: GrantFiled: May 22, 1991Date of Patent: October 12, 1993Assignee: National Starch and Chemical Investment Holding CorporationInventors: Rama S. Chandran, Carmine P. Iovine, Paul R. Mudge, John C. Leighton, Malcolm F. Hallam, Pravin K. Kukkala
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Patent number: 5252646Abstract: Hot melt adhesive compositions are prepared from 20 to 98% by weight of a polylactide homo- or copolymer containing at least 20 molar percent of the lactide component; 2 to 80% by weight of a polar tackifier having a Ring and Ball softening point (as described by ASTM E-26) greater than about 60.degree. C.; 0 to 50% by weight of a plasticizer; 0 to 30% by weight of a wax diluent; 0-3% by weight of a stabilizer; and 0-20% of a polymer. By utilizing a naturally occurring, thermoplastic, biodegradable copolymer as the base polymer, these adhesives advance the state of the art of hot melt adhesives by alleviating the dependence on petroleum based materials and by allowing for the development of hot melt adhesives which either degrade naturally after coming in contact with the soil or which can be composted.Type: GrantFiled: October 29, 1992Date of Patent: October 12, 1993Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, Thomas F. Kauffman, Jules E. Schoenberg, Paul P. Puletti
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Patent number: 5187006Abstract: A formaldehyde-free latent crosslinking monomer represented by the formula ##STR1## in which R.sup.1 and R.sup.2 are C.sub.1 -C.sub.3 alkyl; R.sup.3 is hydrogen, C.sub.1 -C.sub.3 alkyl, or R.sup.4 --C(O)--; and R.sup.4 is C.sub.1 -C.sub.3 alkyl or C.sub.6 -C.sub.8 aryl, contains an allyl group capable of undergoing addition copolymerization and a dialkoxy ethyl group capable of crosslinking under acidic conditions. The monomer can be copolymerized with comonomers to form emulsion polymers for use as formaldehyde-free binders in nonwoven textiles. Methods for the preparation of the monomer, the polymers, and the nonwoven fabrics are described.Type: GrantFiled: August 14, 1992Date of Patent: February 16, 1993Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Dennis Neigel, Carmine P. Iovine
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Patent number: 5187238Abstract: This invention provides polyether polycarboxylate compositions selected from the group consisting of polyether polycarboxylates which may be prepared by oxidizing copolymers of furan and maleic anhydride, and other polyether polycarboxylate compositions prepared by oxidizing novel, intermediate polymers of furan, maleic anhydride, and at least one copolymerizable comonomer, selected from the group consisting of furan, alkenyl alkyl ethers, alkyl acrylates, alkenyl carboxyalkyl ethers, vinyl esters of carboxylic acids, unsaturated carboxylic acids, unsaturated dicarboxylic acids and their anhydrides and esters, and olefins. This invention also provides novel, unoxidized terpolymer intermediates comprising furan, maleic anhydride, and at least one copolymerizable comonomer, other than furan and maleic anhydride, selected from the above group, as well as a process for oxidizing these polymers and the furan and maleic anhydride copolymers.Type: GrantFiled: April 24, 1991Date of Patent: February 16, 1993Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, Rama S. Chandran, John C. Leighton
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Patent number: 5177263Abstract: A formaldehyde-free latent crosslinking monomer represented by the formula ##STR1## in which R.sup.1 and R.sup.2 are C.sub.1 -C.sub.3 alkyl; R.sup.3 is hydrogen, C.sub.1 -C.sub.3 alkyl, or R.sup.4 --C(O)--; and R.sup.4 is C.sub.1 -C.sub.3 alkyl or C.sub.6 -C.sub.8 aryl, contains an allyl group capable of undergoing addition copolymerization and a dialkoxy ethyl group capable of crosslinking under acidic conditions. The monomer can be copolymerized with comonomers to form emulsion polymers for use as formaldehyde-free binders in nonwoven textiles. Methods for the preparation of the monomer, the polymers, and the nonwoven fabrics are described.Type: GrantFiled: September 24, 1991Date of Patent: January 5, 1993Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Dennis Neigel, Carmine P. Iovine
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Patent number: 5126108Abstract: Aminophosphonate-containing polymers of the formula:--B].sub.m [A].sub.nwhereinA represents repeating units from one or more ethylenically unsaturated comonomers;B is ##STR1## wherein R is hydrogen or methyl.X is hydrogen or an alkali metal,Z is CH.sub.2 --P(O)(OX).sub.2 or C.sub.1 -C.sub.6 alkyl, aryl, cyclohexyl or alkaryl,m/n is 0.1 to .5.The novel polymers of the present invention may be used as dispersants for concentrated aqueous particulate slurries, and as corrosion inhibitors and scale inhibitors in water treatment.Type: GrantFiled: February 27, 1991Date of Patent: June 30, 1992Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Carmine P. Iovine
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Patent number: 5087682Abstract: This invention provides polyether polycarboxylate compositions selected from the group consisting of polyether polycarboxylates which may be prepared by oxidizing copolymers of furan and maleic anhydride, and other polyether polycarboxylate compositions prepared by oxidizing novel, intermediate polymers of furan, maleic anhydride, and at least one copolymerizable comonomer, selected from the group consisting of furan, alkenyl alkyl ethers, alkyl acrylates, alkenyl carboxyalkyl ethers, vinyl esters of carboxylic acids, unsaturated carboxylic acids, unsaturated dicarboxylic acids and their anhydrides and esters, and olefins. This invention also provides novel, unoxidized terpolymer intermediates comprising furan, maleic anhydride, and at least one copolymerizable comonomer, other than furan and maleic anhydride, selected from the above group, as well as a process for oxidizing these polymers and the furan and maleic anhydride copolymers.Type: GrantFiled: October 16, 1989Date of Patent: February 11, 1992Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, Rama S. Chandran, John C. Leighton
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Patent number: 5066749Abstract: This invention provides interpolymers comprising repeating units of the structure: ##STR1## wherein m is a mole fraction from 0.70 to 0.95; n is a mole fraction from 0.05 to 0.30; A is derived from at least one ethylenically unsaturated carboxylic acid monomer; B is derived from at least one ethylenically unsaturated carboxylic acid monomer and B is not A; and C is: ##STR2## wherein X is --H, ##STR3## or a combination thereof, R.sup.1 is --H, --CH.sub.3, or --(CH.sub.2).sub.q --CH.sub.3, or a combination thereof, and q is 1-5; R.sup.2 is: ##STR4## or R.sup.3, or a combination thereof, and R.sup.3 is C.sub.8 -C.sub.18 linear or branched alkyl chain; the interpolymer being prepared by polymerizing the monomers in a solvent system in which the monomers and interpolymer are soluble. Also provided is a polymerization process for preparing hydrophobically-modified polycarboxylate builders which are compatible with liquid detergent formulations.Type: GrantFiled: September 11, 1990Date of Patent: November 19, 1991Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Carmine P. Iovine, Michael P. Aronson, David L. Elliott
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Patent number: 5023368Abstract: Aminophosphonate-containing polymers of the formula:--B].sub.m [A].sub.nwhereinA represents repeating units from one or more ethylenically unsaturated comonomers;B is ##STR1## wherein R is hydrogen or methyl,X is hydrogen or an alkali metal,Z is CH.sub.2 --P(O)(OX).sub.2 or C.sub.1 -C.sub.6 alkyl, aryl, cyclohexyl or alkaryl, m/n is 0.01 to 0.5.The novel polymers of the present invention may be used as dispersants for concentrated aqueous particulate slurries, and as corrosion inhibitors and scale inhibitors in water treatment.Type: GrantFiled: June 8, 1989Date of Patent: June 11, 1991Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Carmine P. Iovine
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Patent number: 4948822Abstract: Laminating adhesives are described for forming flexible laminates having high bond strength, and a high degree of both humidity and water resistance. The one-part laminating adhesive compositions incorporate acrylic polymer emulsions prepared by a "core-shell" multistage polymerization process.Type: GrantFiled: February 27, 1989Date of Patent: August 14, 1990Assignee: National Starch and Chemical Investment Holding CorporationInventors: Carmine P. Iovine, James L. Walker