Patents by Inventor Caroline Baudouin

Caroline Baudouin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11026441
    Abstract: The invention relates to an avocado extract rich in polyphenols, containing at least 10% by weight of polyphenols, expressed in gallic acid equivalent relative to the dry extract obtained, wherein said polyphenols contain procyanidins, cafeic acid and cafeic acid derivatives, typically in a proportion of at least 70% by weight, expressed in gallic acid equivalent relative to the total polyphenol content by weight. The invention also relates to a composition comprising an extract according to the invention as active agent and a suitable excipient. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: June 8, 2021
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Alex Saunois, Caroline Baudouin, Sophie Leclere-Bienfait, Sebastien Garnier, Philippe Msika
  • Patent number: 10837958
    Abstract: The invention relates to biomarkers of the skin of children and, in particular, that of infants, having altered expression in the presence of urine. Such markers are particularly advantageous as they allow the skin's response to urine to be monitored. The inventors have developed methods for evaluating the efficacy in vitro of formulations in preventing the harmful effects of urine on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: November 17, 2020
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Caroline Baudouin, Philippe Msika
  • Publication number: 20200256853
    Abstract: The present invention relates to models of reconstructed sensitive skin reproducing the features of sensitive skin, as well as to processes for obtaining such models. The present invention further relates to in vitro processes for testing formulations or active ingredients for the prevention or treatment of sensitive skin.
    Type: Application
    Filed: June 21, 2018
    Publication date: August 13, 2020
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Gaelle BELLEMERE, Stephanie BREDIF, Gaetan BOYER, Caroline BAUDOUIN
  • Publication number: 20200085897
    Abstract: The invention relates to an extract of aerial parts of Maca rich in polyphenols, and also to a composition comprising such an extract and, where appropriate, a suitable excipient. The invention also relates to a process for extracting an extract of aerial parts of Maca rich in polyphenols, and also to the extract that can be obtained by means of said process. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths and/or for use thereof in preventing and/or treating vascular disorders. Finally, the invention relates to a cosmetic care process for the skin, the superficial body growths or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which comprises the administration of such a composition or of such an extract.
    Type: Application
    Filed: September 24, 2019
    Publication date: March 19, 2020
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Alex SAUNOIS, Caroline BAUDOUIN, Sophie LECLERE-BIENFAIT, Sebastien GARNIER, Philippe MSIKA
  • Patent number: 10463593
    Abstract: The present invention relates to the use of a lupin peptide extract to prevent loss of skin firmness or to increase the firmness of skin. Advantageously, the lupin peptide extract can prevent the appearance of cellulite and/or reduce skin cellulite.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: November 5, 2019
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Caroline Baudouin, Sophie Leclere-Bienfait, Philippe Msika, Stéphanie Bredif
  • Patent number: 10444226
    Abstract: A method for determining whether the skin surface of a subject is mature/immature in its organization/function, by taking a skin sample and determining the corneodesmosome distribution within the stratum corneum of the sample by an immunoelectron microscopy method.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: October 15, 2019
    Assignee: LABORATOIRE EXPANSCIENCE
    Inventors: Philippe Msika, Nadège Lachmann, Caroline Baudouin
  • Publication number: 20190242880
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is dry. Such markers are particularly advantageous in that they allow the skin's response to dehydration to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of dehydration on children's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 8, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Stephanie BREDIF, Caroline BAUDOUIN
  • Publication number: 20190234939
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is affected by atopic dermatitis. Such markers are particularly advantageous in that they allow the skin's response to atopic dermatitis to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of atopic dermatitis on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: June 23, 2017
    Publication date: August 1, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Caroline BAUDOUIN, Stephanie BREDIF
  • Patent number: 10196607
    Abstract: A skin model comprises keratinocytes capable of overexpressing filaggrin. A method for evaluating the in vitro activity of a formulation or of at least one active agent on the healing of nipple skin and/or on the reduction of nipple skin inflammation, by bringing said active agent or said formulation into contact with a skin model comprising keratinocytes overexpressing filaggrin and also comprising a lesion, and measuring the level of production of at least one biological marker chosen from lactate dehydrogenase (LDH), TNF?, filaggrin, TGF?1 and ?1 integrin.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: February 5, 2019
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Stephanie Bredif, Caroline Baudouin, Philippe Msika, Marisa Meloni
  • Patent number: 10175230
    Abstract: The invention relates to a method for evaluating the effectiveness of an active ingredient selected from C7 avocado sugars, also called avocado perseose, for preventing or treating a deficiency of the skin barrier, said method comprising the determination of the level of expression and/or activation of at least one biological marker, where said biological marker is selected from epidermal maturation markers, lipid barrier markers, hydric regulation markers and stratum granulosum regulation markers.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: January 8, 2019
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Philippe Msika, Caroline Baudouin, Stephanie Bredif
  • Publication number: 20180369193
    Abstract: The invention relates to an avocado extract rich in polyphenols, containing at least 10% by weight of polyphenols, expressed in gallic acid equivalent relative to the dry extract obtained, wherein said polyphenols contain procyanidins, cafeic acid and cafeic acid derivatives, typically in a proportion of at least 70% by weight, expressed in gallic acid equivalent relative to the total polyphenol content by weight. The invention also relates to a composition comprising an extract according to the invention as active agent and a suitable excipient. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Applicant: Laboratoires Expanscience
    Inventors: Alex SAUNOIS, Caroline BAUDOUIN, Sophie LECLERE-BIENFAIT, Sebastien GARNIER, Philippe MSIKA
  • Patent number: 10143648
    Abstract: The present invention relates to the use of a peptide and glycoside extract of Schizandra fruit as a cutaneous neurosensory agent, for improving the response of the cutaneous neurosensory system, in particular for: —improving cutaneous innervation in the basal state, —combatting age-related loss of cutaneous innervation in the basal state, advantageously for preventing loss of the cutaneous sensitivity and/or combatting thinning of the epidermis, and/or —improving cutaneous perception of the environment, more particularly for combatting burns, extreme cold and/or pain.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: December 4, 2018
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Philippe Msika, Caroline Baudouin, Stéphanie Bredif
  • Patent number: 10092495
    Abstract: The invention concerns a use of C7 sugars and derivatives of formula (I), called avocado perseose, which have, inter alia, a protective activity to epidermal skin cells. These C7 sugars and derivatives are capable of maintaining the expression of markers of adult stem cells, in particular basal stem cells. Avocado perseose can also be used for preventing the deleterious effects of environmental damage. Avocado perseose has a beneficial effect on the conservation of the potential of epidermal stem cells and thus helps maintain skin homeostasis.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: October 9, 2018
    Assignee: LABORATOIRE EXPANSCIENCE
    Inventors: Philippe Msika, Caroline Baudouin
  • Publication number: 20180149640
    Abstract: The invention relates to biomarkers of the skin of children and, in particular, that of infants, having altered expression in the presence of urine. Such markers are particularly advantageous as they allow the skin's response to urine to be monitored. The inventors have developed methods for evaluating the efficacy in vitro of formulations in preventing the harmful effects of urine on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: March 31, 2015
    Publication date: May 31, 2018
    Applicant: Laboratoire Expanscience
    Inventors: Caroline BAUDOUIN, Philippe MSIKA
  • Patent number: 9952201
    Abstract: The invention relates to in vitro methods for testing formulations or active ingredients for preventing the harmful effects of UV on children's skin, in particular children aged three or less. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the harmful effects of UV on the skin of children aged three or less, using a skin model specifically capable of reproducing the characteristics of the skin of children of this age.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: April 24, 2018
    Assignee: LABORATORIES EXPANSCIENCE
    Inventors: Caroline Baudouin, Stephanie Bredif, Philippe Msika
  • Publication number: 20170326061
    Abstract: The present invention relates to the use of a peptide and glycoside extract of Schizandra fruit as a cutaneous neurosensory agent, for improving the response of the cutaneous neurosensory system, in particular for: —improving cutaneous innervation in the basal state, —combatting age-related loss of cutaneous innervation in the basal state, advantageously for preventing loss of the cutaneous sensitivity and/or combatting thinning of the epidermis, and/or—improving cutaneous perception of the environment, more particularly for combatting burns, extreme cold and/or pain.
    Type: Application
    Filed: November 26, 2015
    Publication date: November 16, 2017
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Philippe MSIKA, Caroline BAUDOUIN, Stéphanie BREDIF
  • Publication number: 20170241989
    Abstract: The invention relates to biomarkers of the skin of children and, in particular, that of infants, having altered expression in the presence of urine. Such markers are particularly advantageous as they allow the skin's response to urine to be monitored. The inventors have developed methods for evaluating the efficacy in vitro of formulations in preventing the harmful effects of urine on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: March 31, 2015
    Publication date: August 24, 2017
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventor: Caroline Baudouin
  • Publication number: 20170157019
    Abstract: The present invention relates to the use of a lupin peptide extract to prevent loss of skin firmness or to increase the firmness of skin. Advantageously, the lupin peptide extract can prevent the appearance of cellulite and/or reduce skin cellulite.
    Type: Application
    Filed: July 3, 2015
    Publication date: June 8, 2017
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Caroline BAUDOUIN, Sophie LECLERE- BIENFAIT, Philippe MSIKA, Stéphanie BREDIF
  • Patent number: 9616009
    Abstract: The present invention relates to a composition including at least one C7 sugar, or derivative from esterification of said sugar, and a pharmaceutically acceptable carrier for treating alopecia. The present invention also relates to a method for cosmetically treating hair and nails, said method being intended to stimulate the growth thereof and/or slow the loss thereof. According to said method, a cosmetic composition including at least one C7 sugar, or derivative from esterification of said sugar, is administered. The present invention finally relates to a method for cosmetic care of hair and/or eyelashes and/or nails.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: April 11, 2017
    Assignee: LABORATOIRES EXPANSCIENCE
    Inventors: Caroline Baudouin, Philippe Msika
  • Publication number: 20160326492
    Abstract: A first subject of the invention is a skin model characterized in that it comprises keratinocytes capable of overexpressing filaggrin.
    Type: Application
    Filed: January 12, 2015
    Publication date: November 10, 2016
    Applicant: Laboratoires Expanscience
    Inventors: Stephanie BREDIF, Caroline BAUDOUIN, Philippe MSIKA, Marisa MELONI