Patents by Inventor Caterina Brusasco

Caterina Brusasco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10874878
    Abstract: The present disclosure relates to a particle therapy apparatus for irradiating a target with a charged particle beam. In one implementation, the apparatus includes an isocentric gantry rotatable about an axis and configured to direct a particle beam towards an isocenter of gantry and according to a final beam direction, a magnetic resonance imaging system configured to generate a main magnetic field parallel to the final beam direction, and a passive magnetic shield surrounding the magnetic resonance imaging system, the passive magnetic shield and the magnetic resonance imaging system being synchronously rotatable with the gantry about the axis.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: December 29, 2020
    Assignee: Ion Beam Applications S.A.
    Inventor: Caterina Brusasco
  • Publication number: 20180099158
    Abstract: The present disclosure relates to a particle therapy apparatus for irradiating a target with a charged particle beam. In one implementation, the apparatus includes an isocentric gantry rotatable about an axis and configured to direct a particle beam towards an isocenter of gantry and according to a final beam direction, a magnetic resonance imaging system configured to generate a main magnetic field parallel to the final beam direction, and a passive magnetic shield surrounding the magnetic resonance imaging system, the passive magnetic shield and the magnetic resonance imaging system being synchronously rotatable with the gantry about the axis.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 12, 2018
    Inventor: Caterina BRUSASCO
  • Publication number: 20180099155
    Abstract: The present disclosure relates to a method and a medical apparatus for visualizing on magnetic resonance (MR) images a hadron beam path traversing an organic body. The present method may utilize artefacts in MR image acquisition provoked by the changes in properties of excitable atoms when irradiated by a hadron beam. By synchronizing the hadron pulses with different steps of MR data acquisition, it is possible to identify such artefacts and determine, based on their positions, the hadron beam path and the corresponding position of the Bragg peak.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 12, 2018
    Inventors: Damien PRIEELS, Erik VAN DER KRAAIJ, Sébastien HENROTIN, Caterina BRUSASCO
  • Publication number: 20180099157
    Abstract: The present disclosure relates to a method and a medical apparatus for visualizing a hadron beam traversing an organic body. In one implementation, the method may include capturing a magnetic resonance (MR) image including a volume of irradiated excitable atoms surrounding a hadron beam and having a magnetic susceptibility modified by the hadron beam captured as a hyposignal. For example, a hyposignal may be obtained by saturating the spins of the irradiated excitable atoms before capturing an MR image based on excitation of excitable atoms not affected by the hadron beam.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 12, 2018
    Inventors: Damien PRIEELS, Erik VAN DER KRAAIJ, Sébastien HENROTIN, Caterina BRUSASCO
  • Patent number: 9199093
    Abstract: The present invention relates to a device and method for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications. The actual 3D dose distribution in the patient is tracked during the course of the entire treatment by reconstructing the photon fluences from measured 2D detector responses during irradiation in conjunction with updated patient images.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: December 1, 2015
    Assignee: Ion Beam Applications S.A.
    Inventor: Caterina Brusasco
  • Patent number: 8779375
    Abstract: The present invention relates to a device for dosimetry monitoring of a hadron beam, comprising successive ionization chambers obtained by a series of parallel detector plates separated from each other by a gas filled gap, each detector plate having a collecting part comprising a collecting side insulated from a bias voltage part comprising a bias voltage side and arranged in such a way that the collecting side is facing the bias voltage side of a subsequent detector plate, the resulting assembly of these detector plates forming a plurality of ionization chamber cells, the thicknesses and the choice of the materials of each layer constituting each detector plate as well as the gap of an ionization chamber cell have been selected in order to satisfy the condition that the water equivalent thickness of cell is equal to the length of said cell.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 15, 2014
    Assignee: Ion Beam Applications S.A.
    Inventors: Bruno Marchand, Caterina Brusasco, Sébastien De Neuter, Friedrich Friedl
  • Patent number: 8716663
    Abstract: The present invention relates to a device and method for monitoring and verification of the quality of a radiation treatment beam in conformal radiation therapy, and in particular for IMPT (Intensity Modulated Particle Therapy) applications. The device comprises a 2D electronic detector measuring 2D responses to the delivered treatment beam. These 2D responses are compared with predicted 2D responses and differences in responses are signalled. Based on the measured 2D responses the effectively delivered 3D dose distribution in the target can be reconstructed.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: May 6, 2014
    Assignee: Ion Beam Applications S.A.
    Inventors: Caterina Brusasco, Bruno Marchand
  • Patent number: 8338783
    Abstract: The present invention relates to a dosimetry device for verification of quality of a radiation beam in standard and conformal radiation therapy, and for IMRT (Intensity Modulated Radiation Therapy) applications. The device includes an active area comprising individual radiation detectors. The active area comprises a limited number of lines of radiation detectors, and a number of extra radiation detectors dedicated to the energy measurement of electrons or photons. It also comprises a build-up plate with energy degraders. The energy degraders are located upstream from the extra radiation detectors in the path of the radiation beam.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: December 25, 2012
    Assignees: Ion Beam Applications S.A., Instituto Nazionale di Fisica Nucleare (INFN), Departimento di Fisica Sperimentale, Università Degli Studi
    Inventors: Caterina Brusasco, Flavio Marchetto
  • Publication number: 20120310030
    Abstract: The invention relates to the field of line control of a beam, and especially to a device comprising a plurality of ionisation chambers, enabling the measurement of the dose deposited by an ionising beam and the field of said beam. At least one ionisation chamber is formed from support films having a thickness less than or equal to 100 nm.
    Type: Application
    Filed: September 30, 2010
    Publication date: December 6, 2012
    Inventors: Jean-Marc Fontbonne, Jérôme Perronnel, Bruno Marchand, Caterina Brusasco
  • Publication number: 20120232324
    Abstract: The present invention relates to a device and method for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications. The actual 3D dose distribution in the patient is tracked during the course of the entire treatment by reconstructing the photon fluences from measured 2D detector responses during irradiation in conjunction with updated patient images.
    Type: Application
    Filed: May 6, 2009
    Publication date: September 13, 2012
    Inventors: Caterina Brusasco, Anders Murman
  • Patent number: 8218725
    Abstract: A method is provided for monitoring and/or signalling errors of a radiation therapy apparatus during delivery of a radiation treatment to a target, the radiation therapy apparatus being configurable for a given radiation treatment by means of a beam shaping device. The method includes providing a radiation array detector between the beam shaping device and the target, capable of providing a measured detector response of the radiation treatment; determining a predicted detector response for successive times of the radiation treatment; measuring the measured detector response caused by the radiation beams for corresponding successive times of the radiation treatment; performing a comparison between the measured detector response and the corresponding predicted detector response; signalling in a short reaction time, an error when the comparison results in a difference which exceeds a given threshold.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: July 10, 2012
    Assignees: Ion Beam Applications S.A., Raysearch Laboratories AB
    Inventors: Lutz Müller, Caterina Brusasco, Björn Hårdemark, Johan Löf, Anders Murman
  • Publication number: 20120104270
    Abstract: The present invention relates to a device for dosimetry monitoring of a hadron beam, comprising n successive ionization chambers i obtained by a serie or stack of n+1 parallel detector plates separated from each other by a gas filled gap, each detector plates having a collecting part comprising a collecting side insulated from a bias voltage part comprising a bias voltage side and ranged in a such way that the said collecting side is facing the said bias voltage side of a subsequent detector plate or inversely, each detector plate comprising m layers Lk of materials, the resulting assembly of these detector plates forming a plurality of ionization chamber cells, characterised in that: the thicknesses Ik and the choice of the materials of each layer Lk constituting each detector plate as well as the gap of an ionization chamber cell i have been selected in order to satisfy the equation (I) for each ionization chamber i, where lgi is the gas filled gap distance between two detector plates; Ik is the thickness o
    Type: Application
    Filed: March 22, 2010
    Publication date: May 3, 2012
    Inventors: Bruno Marchand, Caterina Brusasco, Sébastien De Neuter, Friedrich Friedl
  • Patent number: 8160204
    Abstract: The present invention relates to a method and device for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: April 17, 2012
    Assignees: Ion Beam Applications S.A., Raysearch Laboratories AB
    Inventors: Lutz Müller, Caterina Brusasco, Björn Hårdemark, Johan Löf, Anders Murman
  • Publication number: 20110248188
    Abstract: The present invention relates to a device and method for monitoring and verification of the quality of a radiation treatment beam in conformal radiation therapy, and in particular for IMPT (Intensity Modulated Particle Therapy) applications. The device comprises a 2D electronic detector measuring 2D responses to the delivered treatment beam. These 2D responses are compared with predicted 2D responses and differences in responses are signalled. Based on the measured 2D responses the effectively delivered 3D dose distribution in the target can be reconstructed.
    Type: Application
    Filed: May 6, 2009
    Publication date: October 13, 2011
    Inventors: Caterina Brusasco, Bruno Marchand
  • Publication number: 20100215147
    Abstract: The present invention relates to a method and device for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 26, 2010
    Inventors: Lutz Müller, Caterina Brusasco, Björn Hårdemark, Johan Löf, Anders Murman
  • Publication number: 20100177872
    Abstract: A method is provided for monitoring and/or signalling errors of a radiation therapy apparatus during delivery of a radiation treatment to a target, the radiation therapy apparatus being configurable for a given radiation treatment by means of a beam shaping device. The method includes providing a radiation array detector between the beam shaping device and the target, capable of providing a measured detector response of the radiation treatment; determining a predicted detector response for successive times of the radiation treatment; measuring the measured detector response caused by the radiation beams for corresponding successive times of the radiation treatment; performing a comparison between the measured detector response and the corresponding predicted detector response; signalling in a short reaction time, an error when the comparison results in a difference which exceeds a given threshold.
    Type: Application
    Filed: November 2, 2007
    Publication date: July 15, 2010
    Inventors: Lutz Müller, Caterina Brusasco, Björn Hårdemark, Johan Löf, Anders Murman
  • Publication number: 20090200476
    Abstract: The present invention relates to a dosimetry device for verification of quality of a radiation beam in standard and conformal radiation therapy, and for IMRT (Intensity Modulated Radiation Therapy) applications. The device includes an active area comprising individual radiation detectors. The active area comprises a limited number of lines of radiation detectors, and a number of extra radiation detectors dedicated to the energy measurement of electrons or photons. It also comprises a build-up plate with energy degraders. The energy degraders are located upstream from the extra radiation detectors in the path of the radiation beam.
    Type: Application
    Filed: July 27, 2006
    Publication date: August 13, 2009
    Inventors: Caterina Brusasco, Flavio Marchetto
  • Patent number: 7307264
    Abstract: An irradiation apparatus for irradiating by scanning a target volume according to a predetermined dose profile with a scanning beam of charged particles forming an irradiation spot on said target volume, said apparatus comprising: a beam generating device, a reference generator for computing, from said predetermined dose profile, through a dynamic inverse control strategy, the time evolution of commanded variables, these variables being the beam current I(t), the spot position settings x(t),y(t) and the scanning speed settings vx(t), vy(t), a monitor device having means for detecting at each time (t), the actual spot position as a measured position defined by the values xm(t),ym(t) on the target volume, characterised in that said irradiation apparatus further comprises means for determining the differences ex(t), ey(t) between the measured values xm(t), ym(t) and the spot position settings x(t) and y(t), and means for applying a correction to the scanning speed settings vx(t) and vy(t) depending on said d
    Type: Grant
    Filed: November 29, 2002
    Date of Patent: December 11, 2007
    Assignee: Ion Beam Applications S.A.
    Inventors: Caterina Brusasco, Bruno Marchand, Jean-François De Le Hoye, Damien Prieels
  • Publication number: 20050238134
    Abstract: An irradiation apparatus for irradiating by scanning a target volume according to a predetermined dose profile with a scanning beam of charged particles forming an irradiation spot on said target volume, said apparatus comprising: a beam generating device, a reference generator for computing, from said predetermined dose profile, through a dynamic inverse control strategy, the time evolution of commanded variables, these variables being the beam current I(t), the spot position settings x(t),y(t) and the scanning speed settings vx(t), vy(t), a monitor device having means for detecting at each time (t), the actual spot position as a measured position defined by the values xm(t),ym(t) on the target volume, characterised in that said irradiation apparatus further comprises means for determining the differences ex(t), ey(t) between the measured values xm(t), ym(t) and the spot position settings x(t) and y(t), and means for applying a correction to the scanning speed settings vx(t) and vy(t) depending on said
    Type: Application
    Filed: November 29, 2002
    Publication date: October 27, 2005
    Inventors: Caterina Brusasco, Bruno Marchand, Jean-Francois De Le Hoye, Damien Prieels