Patents by Inventor Catherine Elizabeth Majors

Catherine Elizabeth Majors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230035412
    Abstract: A method for detecting an analyte is described in which the simultaneously binding of two fusion proteins (i.e., a sandwich assay in solution) is used, bringing two halves of a split enzyme together to produce product, which is detected via a FRET-based biosensor. The method may incorporate an autocatalytic feedback loop that responds to enzymatic product by producing more product to provide ultrasensitive, bistable detection of analyte that is tunable over several orders of magnitude. This system is broadly applicable for protein and small molecule detection.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 2, 2023
    Applicant: Northwestern University
    Inventors: Keith E.J. Tyo, Catherine Elizabeth Majors