Patents by Inventor Cecilia Anneren
Cecilia Anneren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10125349Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or Inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: GrantFiled: March 27, 2014Date of Patent: November 13, 2018Assignee: GE Healthcare Bio-Sciences ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Patent number: 10011816Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: GrantFiled: October 7, 2016Date of Patent: July 3, 2018Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Patent number: 9976117Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: GrantFiled: October 7, 2016Date of Patent: May 22, 2018Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Patent number: 9944895Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: GrantFiled: June 22, 2016Date of Patent: April 17, 2018Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Patent number: 9845455Abstract: The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.Type: GrantFiled: April 19, 2013Date of Patent: December 19, 2017Assignee: GE Healthcare Bio-Sciences ABInventors: Cecilia Anneren, Christian Kaisermayer, Mats Lundgren, Johanna Tschop, Therese Lundstrom, Ann-Christin Magnusson, Gerald Blueml
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Patent number: 9714415Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or Inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: GrantFiled: October 7, 2016Date of Patent: July 25, 2017Assignee: GE Healthcare Bio-Sciences ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Publication number: 20170096642Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or Inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: ApplicationFiled: October 7, 2016Publication date: April 6, 2017Inventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Publication number: 20170022471Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: ApplicationFiled: October 7, 2016Publication date: January 26, 2017Inventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Publication number: 20160340646Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: ApplicationFiled: June 22, 2016Publication date: November 24, 2016Inventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Publication number: 20160053225Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or Inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.Type: ApplicationFiled: March 27, 2014Publication date: February 25, 2016Applicant: GE Healthcare Bio-Sciences ABInventors: Sara Pijuan Galito, Christoffer Tamm, Cecilia Anneren
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Publication number: 20130236970Abstract: The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.Type: ApplicationFiled: April 19, 2013Publication date: September 12, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: CECILIA ANNEREN, CHRISTIAN KAISERMAYER, MATS LUNDGREN, JOHANNA TSCHOP, THERESE LUNDSTROM, ANN-CHRISTIN MAGNUSSON, GERALD BLUEML
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Publication number: 20120214230Abstract: The present invention relates to a fast a simple coating procedure for coating of cell culture and/or handling surfaces to prevent cell adhesion and growth. The invention relates to a cell culture/handling product coated with phenyl dextran, as well as methods of producing and using it.Type: ApplicationFiled: October 21, 2010Publication date: August 23, 2012Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Cecilia Anneren, Gunnar Glad, Christine Sund Lundstrom
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Publication number: 20120156779Abstract: The present invention relates to a method for cell expansion. In the method, preferably a cell culture product is used, such as a microcarrier, or other adherent cell culture surface, comprising degradable polysaccharide, preferably starch, modified with small molecular weight cell-binding ligands. This allows recovery (detachment) of adhered cells to be aided by degradation of the culture surface with enzymatic agents, such as amylase. The method for cell expansion comprises the following steps: a) adding cells, culture medium and cell culture surface comprising a degradable polysaccharide with guanidine group containing ligands to a bioreactor; b) expanding said cells by adherent cell culture; and c) aiding the detachment of said cells by exposing them to a polysaccharidase to degrade the culturing surface.Type: ApplicationFiled: August 23, 2010Publication date: June 21, 2012Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Cecilia Anneren, Andreas Axen, Asa Bjurling, Christine Sund Lundstrom, James Van Alstine, Gunnar Froman
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Publication number: 20110070648Abstract: The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.Type: ApplicationFiled: May 11, 2009Publication date: March 24, 2011Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Cecilia Anneren, Linnea Pauler
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Publication number: 20040171563Abstract: The present invention relates to a novel use of a tyrosine kinase inhibitor or blocking agent. More precisely, it relates to use of an inhibitor of tyrosine kinase for production of a drug for prevention/treatment of type I diabetes mellitus, wherein the inhibitor is a GTK (BSK, IYK, FRK, RAK) tyrosine kinase.Type: ApplicationFiled: April 26, 2004Publication date: September 2, 2004Inventors: Michael Welsh, Cecilia Anneren