Patents by Inventor Chandan K. Sen

Chandan K. Sen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100035798
    Abstract: The invention provides methods, delivery devices, and compositions for topically oxygenating hypoxic tissue with a hemoglobin-based oxygen earner (HBOC), such as Oxyglobin (Oxyb) in order to promote wound healing and/or reducing hypoxia in post-harvest transplant tissue. The invention can be used, among other things, to stimulate angiogenesis and blood flow at a wound site, reduce wound dilation, and promote wound contraction, thereby increasing the overall rate of wound healing. The invention can also be used, among other things, to reduce oxidative stress in pre-implantation donor organ tissue, as well as stimulate the proliferation of granulation tissue, vessel growth, and promote epithelial healing in transplant tissue once it has been implanted.
    Type: Application
    Filed: September 17, 2007
    Publication date: February 11, 2010
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Chandan K. Sen, Sashwati Roy, Savita Khanna
  • Patent number: 6387945
    Abstract: A compound is provided having the formula I: wherein the variables are defined in the specification. Methods of making the compounds, compositions including the compounds and methods of treatment of conditions involving reactive oxygen species are also provided.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: May 14, 2002
    Assignee: The Regents of the University of California
    Inventors: Lester Packer, Oren Tirosh, Chandan K. Sen, Sashwati Roy
  • Publication number: 20010039292
    Abstract: A compound is provided having the formula I: 1
    Type: Application
    Filed: May 9, 2001
    Publication date: November 8, 2001
    Applicant: The Regents Of The University of California, a California corporation
    Inventors: Lester Packer, Oren Tirosh, Chandan K. Sen, Sashwati Roy
  • Patent number: 6235772
    Abstract: A compound is provided having the formula I: as defined in the specification. Methods of making the compounds, compositions including the compounds and methods of treatment of conditions involving reactive oxygen species are also provided.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: May 22, 2001
    Assignee: The Regents of the University of California
    Inventors: Lester Packer, Oren Tirosh, Chandan K. Sen, Sashwati Roy
  • Patent number: 6090842
    Abstract: A compound is provided having the formula I: ##STR1## wherein R.sup.1 and R.sup.2 independently denote a methylene, ethylene or unbranched or branched C.sub.3-16 alkylene, alkenylene or alkynylene group which is unsubstituted or substituted with one or more halogen, hydroxyl or amine groups, wherein in the unbranched or branched C.sub.3-16 alkylene, alkenylene or alkynylene group an internal alkylene carbon atom in the carbon backbone thereof can be replaced by an oxygen atom,R.sup.3 and R.sup.4(i) independently denote(a) hydrogen,(b) a methyl, ethyl, vinyl or unbranched or branched C.sub.3-16 alkyl, alkenyl or alkynyl group which is unsubstituted or substituted with one or more halogen, hydroxyl or amine groups, wherein in said unbranched or branched C.sub.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: July 18, 2000
    Assignee: The Regents of the University of California
    Inventors: Lester Packer, Oren Tirosh, Chandan K. Sen, Sashwati Roy