Patents by Inventor Chandraiah Lagisetti

Chandraiah Lagisetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dual CLK/CDK1 inhibitors for cancer treatment
    Patent number: 11337981
    Abstract: The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: May 24, 2022
    Assignee: SRI International
    Inventors: Thomas R. Webb, Jaehyeon Park, Chandraiah Lagisetti
  • DUAL CLK/CDK1 INHIBITORS FOR CANCER TREATMENT
    Publication number: 20200390772
    Abstract: The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: May 28, 2020
    Publication date: December 17, 2020
    Inventors: Thomas R. Webb, Jaehyeon Park, Chandraiah Lagisetti
  • Dual CLK/CDK1 inhibitors for cancer treatment
    Patent number: 10722515
    Abstract: The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: July 28, 2020
    Assignee: SRI International
    Inventors: Thomas R. Webb, Jaehyeon Park, Chandraiah Lagisetti
  • DUAL CLK/CDK1 INHIBITORS FOR CANCER TREATMENT
    Publication number: 20190255059
    Abstract: This disclosure generally relates to dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: September 29, 2017
    Publication date: August 22, 2019
    Inventors: Thomas R. Webb, Jaehyeon Park, Chandraiah Lagisetti
  • Anticancer compounds
    Patent number: 9682993
    Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: June 20, 2017
    Assignee: St. Jude Children's Research Hospital
    Inventors: Thomas R Webb, Chandraiah Lagisetti
  • ANTICANCER COMPOUNDS
    Publication number: 20160009728
    Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 9, 2013
    Publication date: January 14, 2016
    Inventors: Thomas R Webb, Chandraiah Lagisetti
  • Anticancer compounds and methods of making and using same
    Patent number: 8969405
    Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: March 3, 2015
    Assignee: St. Jude Children's Research Hospital
    Inventors: Thomas R. Webb, Chandraiah Lagisetti
  • ANTICANCER COMPOUNDS AND METHODS OF MAKING AND USING SAME
    Publication number: 20110178098
    Abstract: In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 22, 2009
    Publication date: July 21, 2011
    Inventors: Thomas R. Webb, Chandraiah Lagisetti