Patents by Inventor Charity Tucker BECHTEL

Charity Tucker BECHTEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF CONJUGATING AN AGENT TO A THIOL MOIETY IN A PROTEIN THAT CONTAINS AT LEAST ONE TRISULFIDE BOND
    Publication number: 20220372141
    Abstract: The invention provides improved methods of conjugating an agent to a thiol moiety in a protein that contains at least one disulfide bond and at least one trisulfide bond. Exemplary embodiments include the production of antibody drug conjugates substantially free of impurities created in the presence of reactive sulfide moieties in the production processes.
    Type: Application
    Filed: May 24, 2022
    Publication date: November 24, 2022
    Applicant: Genentech, Inc.
    Inventors: Jayme FRANKLIN, Xin Xin LIN, Jeffrey GORRELL, Timothy TULLY, Matthew HUTCHINSON, Charity Tucker BECHTEL
  • Methods of conjugating an agent to a thiol moiety in a protein that contains at least one sulfide bond
    Patent number: 11370838
    Abstract: The invention provides improved methods of conjugating an agent to a thiol moiety in a protein that contains at least one disulfide bond and at least one trisulfide bond. Exemplary embodiments include the production of antibody drug conjugates substantially free of impurities created in the presence of reactive sulfide moieties in the production processes.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: June 28, 2022
    Assignee: GENENTECH, INC.
    Inventors: Jayme Franklin, Xin Xin Lin, Jeffrey Gorrell, Timothy Tully, Matthew Hutchinson, Charity Tucker Bechtel
  • METHODS OF CONJUGATING AN AGENT TO A THIOL MOIETY IN A PROTEIN THAT CONTAINS AT LEAST ONE SULFIDE BOND
    Publication number: 20170209593
    Abstract: The invention provides improved methods of conjugating an agent to a thiol moiety in a protein that contains at least one disulfide bond and at least one trisulfide bond. Exemplary embodiments include the production of antibody drug conjugates substantially free of impurities created in the presence of reactive sulfide moieties in the production processes.
    Type: Application
    Filed: January 24, 2017
    Publication date: July 27, 2017
    Inventors: Jayme FRANKLIN, Xin Xin LIN, Jeffrey GORRELL, Timothy TULLY, Matthew HUTCHINSON, Charity Tucker BECHTEL