Patents by Inventor Charlene J. Williams

Charlene J. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Primers and methods for detecting mutations in the procollagen II gene (COL2A1) that indicate a genetic predisposition for a COL2A1-associated disease
    Patent number: 5948611
    Abstract: The invention provides probes and primers for amplifying certain regions of genes for structural proteins of cartilage and methods for detecting mutations in these genes isolated from the nucleic acid of cells suspected of exhibiting mutant structural protein gene expression or having mutant structural protein genes. The invention also provides methods for determining a genetic predisposition for a disease that alters the structure or function of cartilage because of a mutation in a gene for a structural protein of cartilage in a mammal.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: September 7, 1999
    Assignee: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Leena Ala-Kokko, Charlene J. Williams, Pertti Ritvaniemi, Clinton Baldwin, Ian Hopkinson, Nilofer Nina Ahmad