Patents by Inventor Charles A. Blaha

Charles A. Blaha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075193
    Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.
    Type: Application
    Filed: May 3, 2023
    Publication date: March 7, 2024
    Inventors: Shuvo Roy, Rishi Kant, Andrew Posselt, Shang Song, Willieford Moses, Charles Blaha
  • Patent number: 11666691
    Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: June 6, 2023
    Assignee: The Regents of the University of California
    Inventors: Shuvo Roy, Rishi Kant, Andrew Posselt, Shang Song, Willieford Moses, Charles Blaha
  • Publication number: 20220016324
    Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.
    Type: Application
    Filed: June 9, 2021
    Publication date: January 20, 2022
    Inventors: Shuvo Roy, Rishi Kant, Andrew Posselt, Shang Song, Willieford Moses, Charles Blaha
  • Patent number: 11033668
    Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: June 15, 2021
    Assignee: The Regents of the University of California
    Inventors: Shuvo Roy, Rishi Kant, Andrew Posselt, Shang Song, Willieford Moses, Charles Blaha
  • Publication number: 20190216998
    Abstract: (57) Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.
    Type: Application
    Filed: March 7, 2017
    Publication date: July 18, 2019
    Applicant: The Regents of the University of California
    Inventors: Shuvo ROY, Rishi KANT, Andrew POSSELT, Shang SONG, Willieford MOSES, Charles BLAHA
  • Patent number: 10256202
    Abstract: A durable bond pad structure is described that facilitates highly durable electrical connections to semiconductor microelectronics chips (e.g., silicon carbide (SiC) chips) to enable prolonged operation over very extreme temperature ranges.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: April 9, 2019
    Assignee: The United States of America as Represented by the Administrator of National Aeronautics and Space Administration
    Inventors: David J. Spry, Dorothy Lukco, Philip G. Neudeck, Carl W. Chang, Liangyu Chen, Roger D. Meredith, Kelley M. Moses, Charles A. Blaha, Jose M. Gonzalez, Glenn M. Beheim, Kimala L. Laster
  • Patent number: 10172966
    Abstract: Disclosed herein are methods, processes, devices, and compositions for the treatment of target cells and/or tissues, the treatment comprising identifying the target cell with positron emission tomography and then directing a epithermal neutron toward the identified target cell. In various aspects, the target cells and/or tissues take up and metabolize boronated glucose and radioactive fluorinated glucose molecules.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: January 8, 2019
    Inventor: Charles Blaha
  • Publication number: 20160158391
    Abstract: Disclosed herein are methods, processes, devices, and compositions for the treatment of target cells and/or tissues, the treatment comprising identifying the target cell with positron emission tomography and then directing a epithermal neutron toward the identified target cell. In various aspects, the target cells and/or tissues take up and metabolize boronated glucose and radioactive fluorinated glucose molecules.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Inventor: Charles Blaha
  • Publication number: 20060195157
    Abstract: The present invention provides a method for modulating or regulating levels of a neurochemical in an individual using deep brain stimulation. More particularly, the invention relates to a method of treating neurological and psychiatric diseases by providing a feedback loop capable of maintaining central and/or peripheral nervous system neurochemical levels in an individual.
    Type: Application
    Filed: October 5, 2005
    Publication date: August 31, 2006
    Inventors: Kendall Lee, Charles Blaha
  • Publication number: 20030016116
    Abstract: A method of depositing a thin metal film using photolithography is disclosed. The method includes the deposition of a sacrificial metal layer on a substrate. Photolithography processing forms a pattern on the sacrificial metal layer that is removed prior to sputter deposition of the thin metal film.
    Type: Application
    Filed: July 23, 2001
    Publication date: January 23, 2003
    Inventor: Charles A. Blaha
  • Patent number: 5109398
    Abstract: An apparatus and method for conducting and imaging vertical flow tests through a sample of porous material on-line in a CT scanner, characterized by a sample of porous material, such as a core sample, having a vertical axis and a transversely extending horizontal axis defining a scan plane to be imaged by the CT scanner. The sample is of uniform transverse width in the scan plane and has top and bottom end surfaces and opposite transverse side surfaces. The invention is further characterized by opposite filler bodies, of a material having an X-ray attenuation characteristic similar to the X-ray attenuation characteristic of the sample, juxtaposed against the side surfaces of the sample, respectively. The filler bodies have inner surface adjacent the sample and outer side surfaces that are round in the scan plane for forming with the sample a round shape for scanning in the scan plane. Also provided are top and bottom end pieces in fluid communication with the top and bottom surfaces, respectively.
    Type: Grant
    Filed: February 22, 1990
    Date of Patent: April 28, 1992
    Assignee: BP America Inc.
    Inventors: Patricia K. Hunt, Michael J. King, Charles Blaha