Patents by Inventor Charles Cullis Hinckley

Charles Cullis Hinckley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Containment cuvette for PCR and method of use
    Patent number: 6645758
    Abstract: A cuvette and a method of use prevent nucleic acid amplified by PCR technology from being released to the atmosphere, while still proceeding to a detection step to determine whether or not the nucleic acid is present. Detection reagents are either pre-incorporated into compartments in the cuvette or added after amplification. In the latter case, a check valve prevents amplified nucleic acid from being released. Transfer of liquids between compartments is achieved via the use of flexible compartment walls and an external pressure source, or via pistons that are part of the cuvette and operate on the compartments as a piston within a piston chamber.
    Type: Grant
    Filed: September 28, 1992
    Date of Patent: November 11, 2003
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Paul Nicholas Schnipelsky, Leonard Joseph Seaberg, Charles Cullis Hinckley, Jeffrey Allen Wellman, William Harold Donish, John Bruce Findlay
  • Blocked compartments in a PCR reaction vessel
    Patent number: 5811296
    Abstract: A flexible cuvette comprising enclosed chambers and passageways for filling and/or passing liquid thereinto or therethrough, the chambers and passageways being formed by plastic sheets blocked together prior to use to eliminate air bubbles, by an amount sufficient to require at least 0.8 g/cm of lineal width peel-apart force.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: September 22, 1998
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: John Benjamin Chemelli, Charles Cullis Hinckley