Abstract: Tissue scraper element for medical use in extracting undesired body tissue, e.g. a natural eye lens, by mechanical vibratory contact to disintegrate the tissue and by accompanying flushing fluid flow removal of the disintegrated tissue from the tissue site, the element including a longitudinal shank whose base end in use is mounted on a hand held instrument for longitudinal back and forth vibratory movement, and whose free end terminates in a tip extending crosswise of the shank longitudinal axis. The shank has an internal flow passage, and the tip terminates in a laterally outwardly directed scraper edge and has an internal flow channel communicating the shank passage with a mouth adjacent the scraper edge. Upon contacting the scraper edge against the undesired tissue in a direction crosswise of the shaft longitudinal axis, while subjecting the shank and tip to such vibratory movement and accompanying flushing fluid flow via the tip mouth, the tissue will be disintegrated and removed.

Abstract: An injector head forming a hollow cone of spreadable leaves is partially inserted into a minimum size eye incision to inject a temporarily folded intraocular lens into the eye without stressing the incision. An injector device having a holder with a bore holding the lens in folded state is connected to the cone, and a plunger of the device inserted in the bore pushes the lens into and through the cone for controlled gradual injection into the eye and simultaneous controlled gradual unfolding therein.

Abstract: A surgical instrument for seating an intraocular lens in the posterior capsule of an eye in place of a removed cataracted natural lens includes a longitudinally extending shank and a band attached to the shank and forming a closed loop. The loop extends outwardly of the S-shaped tip portion of the shank for holding the intraocular lens in a plane which is generally parallel to and laterally displaced from the longitudinal axis of the shank. The band has a first end connected with the shank for movement therewith, and a second end connected to a support member located in the shank for movement therewith and relative thereto. The member, when displaced in the shank bore relative to the shank, tears the band, breaking the loop. Thereby, upon withdrawal of the instrument from the eye, the band is withdrawn together with the instrument without disturbing the seating of the intraocular lens in the posterior capsule.

Abstract: The present invention provides a biologically compatible collagenous reaction product comprising ethylenically unsaturated or polymeric substituted collagen, the monomeric substituents being essentially free of nitrogen, e.g., methacrylate styrene, polyvinyl, ethylene. The collagenous reaction product can be polymerized, e.g., by exposure to UV irradiation, chemical agents or atmospheric oxygen, and molded to form useful medical implant articles. Methods of preparation are also provided.

Abstract: An instrument for aspirating and irrigating unwanted material from all regions of the capsule of the eye, especially suitable for cataract removal, including an instrument having a hooked tip portion at the operative end thereof. The hooked tip portion is capable of being deformed into a straightened portion for entering the eye. The straightened portion resiliently returning to its hooked configuration upon release of an outside force, whereby the hooked tip portion is capable of access to inner peripheral regions of the posterior capsule which previously were accessible only with great difficulty. The instrument is capable of supplying treatment fluid to the region of the eye in question for irrigating the region and the instrument is capable of aspirating the region for removal of fluid and unwanted tissue.

Abstract: Two piece intraocular lens for successive insertion of the two pieces through a minimum size incision into the eye for assembly therein to form the two piece lens for implantation in the eye, including an oblong lens body and a separate ring shaped collapsible tension frame therefor containing light-masking material for inhibiting light rays directed toward the outer edge portions of the lens body from being scattered thereby toware the retina after the assembly two pieces lens has been implanted in the eye.

Abstract: The present invention provides a non-biodegradable corneal implant comprising (1) a polymerized transparent collagenous core having acylated amine or esterified carboxyl groups, and (2) a polymerized periphery surrounding the core, the periphery comprising fibrous collagen, e.g., Type I, being in the form of fibrils under suitable physiological conditions, or fibrillar collagenous material prepared from intact tissue. A method of preparing such an implant is also provided.

Abstract: Production of a chemically modified, crosslinkable, telopeptide-containing, naturally crosslinked, solubilized collagen from tissue obtained from a sole human donor, for implanting in the same donor, by chemically modifying the tissue, e.g. by acylation and/or esterification, to form an autoimplantable, crosslinkable, telopeptide-containing naturally crosslinked, collagen, product, as a completely solubilized collagen solution, optionally of high index of refraction for correcting sight, or as a partially solubilized collagen suspension; and use of the product for altering the condition of in situ tissue of the same human donor by autoimplantation, such as by crosslinking the product to form an implant device, by placing an effective amount of the product at the tissue site and crosslinking the product in situ, or by partially crosslinking the product and placing an effective amount thereof at the tissue site and optionally further crosslinking the product in situ.

Abstract: Decentered intraocular lens, usable to correct high myopia of an intact natural lens in an eye having a decentered pupil, by insertion through an eye incision and implanting in the anterior chamber at minimum risk of contacting the natural lens. The intraocular lens includes a lens body having a thickened outer edge and a concave face, and a pair of opposed haptics each terminating in a transverse edge having a pair of laterally spaced lobes to engage adjacent eye tissue at a corresponding pair of spaced tissue points, the transverse edges being of unequal length and arranged at respective distances from the lens body so that the lobes lie in a circle whose center is eccentric to the lens body optical axis, to position the lens body in spaced relating to the natural lens, decentered relative to the circle and eye optical axis and centered relative to the decentered pupil, with the lens body outer edge masked by the iris to inhibit transmission thereat of entering edge glare causing light rays.

Abstract: Corrective intraocular lens for use with an intact natural eye lens, by insertion through an incision into the eye and implantation therein in spaced relation to the natural lens, including a lens body having a pair of opposed haptics constituting a first insertable leading haptic and a last insertable trrailing haptic, each outwardly terminating in a transverse edge having a pair of laterally spaced apart and outwardly projecting contact lobes for engaging an adjacent eye tissue portion at a corresponding pair of spaced apart tissue points, the trailing haptic transverse edge having a 2-3 mm length, and the leading haptic transverse edge having a length larger than 2-3 mm and preferably about as large as the lens body diameter, such that the 2-3 mm length transverse edge of the last inserted haptic may be passed inwardly of the incision under minimum deflection of the intraocular lens and minimum risk of contact with the natural lens by the intraocular lens during implantation.

Abstract: Clip-on optic assembly for clipping in situ onto a previously implanted intraocular lens to change its optical characteristics without removal from the eye, comprising a lens body having a plurality of spaced apart resilient clip members extending therefrom and outwardly terminating in clips for gripping the implanted lens peripheral edge to clip the assembly thereon. At least one clip is formed as a bent end sufficiently resilient for temporary unbending and displacement over and across the implanted lens peripheral edge to grip the clip thereon, e.g. with the clips being of selected length for maintaining the lens body optical axis concentric or eccentric to the implanted lens optical axis, the assembly upon insertion into the eye being clipped onto the implanted lens such that a bent end clip is last manipulated onto such peripheral edge.

Abstract: Overlapping two piece intraocular lens for successive insertion of the two pieces through a minimum size incision into the eye for assembly therein to form the two piece lens for implantation in the eye, including a lens body and a separate ring shaped collapsible filament, tension frame therefor containing light-masking material to inhibit light rays directed toward the lens body outer edge portions from being scattered thereby toward the retina after the assembled overlapping two piece lens has been implanted in the eye.

Abstract: Corrective intraocular lens for use with an intact natural eye lens, by insertion through an incision into the eye and implantation therein in spaced relation to the natural lens, including a lens body having a pair of opposed haptics constituting a first insertable leading haptic and a last insertable trailing haptic, each outwardly terminating in a transverse edge having a pair of laterally spaced apart and outwardly projecting contact lobes for engaging an adjacent eye tissue portion at a corresponding pair of spaced apart tissue points, the trailing haptic transverse edge having a 2-3 mm length, and the leading haptic transverse edge having a length larger than 2-3 mm and preferably about as large as the lens body diameter, such that the 2-3 mm length transverse edge of the last inserted haptic may be passed inwardly of the incision under minimum deflection of the intraocular lens and minimum risk of contact with the natural lens by the intraocular lens during implantation.

Abstract: An intraocular lens for implantation within an eye after cataract surgery. The intraocular lens has a haptic having an elongated gently curving seating portion having a free end and a weakened portion about which such seating portion pivots. The weakened portion is spaced from the fulcrum formed at the location at which the haptic is anchored to the lens body such that the free end of the seating portion moves toward the lens body in response to compression of the seating portion toward the lens body for facilitating seating thereof, while minimizing the risk of injury to the delicate membranes in the eye by outwardly extending distal portions of the haptics.

Abstract: Bipartite intraocular lens, insertable in temporarily contracted condition through a minimum size incision into the eye for implantation therein, including a haptic containing oblong lens body coactively mounted in a ring shaped, partially contractible, differential thickness, unitary tension frame formed of a tension band having light-masking contractible wings for inhibiting light rays directed toward the outer edge portions of the lens body from being scattered thereby toward the retina after the lens has been implanted in the eye.

Abstract: Composite lens, especially an intraocular lens for insertion through an incision into an eye and desirably containing haptics, comprising a flat, partially hollow laminate optic, formed by a pair of relatively thin, sheet-like elements having opposed interior surfaces, at least one such element constituting a protected Fresnel lens defining the interior surface of the element as a discontinuous surface formation of a concentric series of annular prisms, the interior surfaces being peripherally sealed together to define therebetween a counterpart series of permanent captive gas enclosing, liquid free, spaces of different index of refraction from that of the elements, preferably with the elements being formed of flexible, temporarily deformable material and together sized to provide the optic with a comparatively thin thickness in relation to its diameter, permitting its deformation into a reduced girth cylindrical shape for eye insertion through a minimum size corneal incision, after which the lens will return

Abstract: Intraocular lens for implantation in the posterior chamber of an eye, following extracapsular removal of the natural eye lens, including a lens assembly having an anterior surface formation and a posterior surface formation, at least a portion of the posterior surface formation constituting a planar contact region adapted to be seated against the adjacent planar tissue surface of the posterior capsule to form a connection interface for permanent anchoring of the lens assembly thereat, the contact region being provided with a roughened surface area defined by a series of ordered narrow linear depressions therein extending generally transversely of the plane of the contact region, for accelerated adhesion of the tissue of the adjacent posterior capsule part to the depressions and enhanced anchoring of the lens assembly to the posterior capsule part, to prevent dislodgment of the implanted intraocular lens.

Abstract: Lens forceps and method of use thereof for extractive removal from the interior of an eye through a corneal incision of a surgically severed segmental lens fragment, the forceps contemplating a manually manipulatable eye lens size clamp of two relatively longitudinally movable parts, including a scoop part having a handle provided with a crescent shaped scoop extending therefrom and defining an upwardly open receiving trough of conforming size and shape to the profile of such a fragment for receiving the fragment therein, and a cover part having a handle provided with a cover extending therefrom, the parts being arranged for manually controlled relative longitudinal movement therebetween and, in one position of such movement, for manually controlled removable stationary engagement of the handles and corresponding positioning of the cover over the scoop to form therewith a cage to retain the fragment for permitting removal thereof from the eye through the corneal incision.

Abstract: Method of inserting an intraocular lens, having an optic and haptics of flexible material, through an incision into an eye, including preliminarily compressing the lens into a generally cylindrical shape, e.g. in a tubular sleeve, immersing the compressed lens in an eye compatible liquid, e.g. water, freezing the liquid in situ to form a generally cylindrical frozen plug, and inserting the frozen plug, containing the compressed lens therein, through the incision into the interior of the eye, e.g. by positioning such sleeve external to the eye at the incision and pressing the frozen plug by a plunger in the direction of the eye so as to force the plug out of the sleeve and in unconfined condition through the incision, such that the inserted plug will thaw in the eye interior and release the lens to its original, undeformed state, whereupon the original state lens may be seated in place in the eye.

Abstract: An artificial lens adapted for implantation in the human eye and the method for implanting such lens. The lens is of pliable material so that it may be folded or curled for insertion through a minimum length incision. It has a medial optic portion having a posterior concave surface corresponding to the anterior surface of the natural lens when the latter is in its flattest natural condition, and haptic portions for seating the lens in the eye such that the posterior concave surface of the medial optic portion of the artificial lens seats directly against the anterior surface of the natural lens of the eye which remains in and is not removed from the eye.