Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4 The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4) and compositions comprising such antibodies or antigen-binding fragments thereof. In a specific aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human B7-H4 increase T cell proliferation, increase interferon-gamma production, and/or deplete B7-H4 expressing cells via ADCC activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody or antigen-binding fragment thereof that specifically binds to human B7-H4.

Abstract: Methods of identifying and using SLAMF1 antagonists are provided.

Abstract: The present invention relates to a data distribution device comprising of a core electronics suite having at least two data ports where each port is in communication with its own network transport medium. At least two broadband transceivers, each in communication with its own broadband data port, enable sending and receiving of broadband data signals. At least two converters, each in communication with its own transceiver, enable the conversion of RF modulated data signals into data packets and the conversion of data packets into RF modulated data signals.

Abstract: The present invention relates to a data distribution device comprising of a core electronics suite having at least two data ports where each port is in communication with its own network transport medium. At least two broadband transceivers, each in communication with its own broadband data port, enable sending and receiving of broadband data signals. At least two converters, each in communication with its own transceiver, enable the conversion of RF modulated data signals into data packets and the conversion of data packets into RF modulated data signals.

Abstract: A method and apparatus for disinfecting an entire room in one operation that includes providing a sufficiently large container having a liquid disinfectant and aerosol and a manually actuated valve and nozzle that includes a spray pattern for a uniform distribution of aerosol spray, said container being sized to completely disinfect a room of a specific surface area and volume. To use the device, the aerosol container is placed at a central location in the room based on its distribution pattern and, once activated, the room will be kept closed so that the entire disinfectant contents can be continuously dispersed for total disinfectant of the room in a single operation until all the contents of the container have been emptied.

Abstract: A method and system for printing medical labels. A hand-held, portable computer, a printer and a wireless data communication interface communicating between the computer and the printer are provided. Medical data are organized in the computer into predetermined type files and are preferably further organized into sub-files for presentation on a display associated with the computer. A user selects from among the files through use of the computer, preferably by touching the display. The computer communicates ultimately selected data to the printer and the printer prints the data on a label which is applied to a medical document.

Abstract: A method and system for printing medical labels. A hand-held, portable computer, a printer and a wireless data communication interface communicating between the computer and the printer are provided. Medical data are organized in the computer into predetermined type files and are preferably further organized into sub-files for presentation on a display associated with the computer. A user selects from among the files through use of the computer, preferably by touching the display. The computer communicates ultimately selected data to the printer and the printer prints the data on a label which is applied to a medical document.

Abstract: This invention provides a mounting structure 10 for releasably securing an auditorium seating unit to the floor. The mounting structure includes a bracket support 12 which is a rectangular casing 32 equipped with openings 40 & 42 interconnected with a pathway slot 46. The mounting structure includes a plate member 16 that is permanently part of the leg or stanchion of the seating unit. The plate member has a stud fastener 52 and a nut/bolt arrangement 62 that depends from the plate member and are received in the openings 40 & 42. The stud 52 and the nut/bolt arrangement 62 are received in the pathway slot 46 and the fasteners 52 & 62 are guided into the openings 40 & 42. The stud 52 and nut/bolt 62 secure the seating unit to the bracket support 12. Cover plates 114 serve to cover the exposed bracket support 12 absent the seating unit 28. The plate member is equipped with a guide element 102 to facilitate locating the openings when restoring the seating unit to this auditorium.

Abstract: An optical element having a light carrying medium through which light can propagate by total internal reflection. The light carrying medium has at least one surface. A layer is positioned adjacent the surface and is of a porous first material of sufficient porosity and with pores which are vacant or contain a second material having an index of refraction lower than that of the light carrying medium, such that the layer reduces total internal reflection in the light carrying medium less than would be reduced using a non-porous layer of the same dimensions of only the first material. A light integrator and scanner using such integrator are also provided.

Abstract: A spectral filtration system comprising a non-imaging optic having entry and exit faces, the exit face being tilted relative to the entry face, and a filter positioned so as to receive light from, or transmit light to, a face of the non-imaging optic.

Abstract: A border treatment is supplied to an image which is to be processed by using an algorithm operation on a neighborhood surrounding each image pixel of the image. The border provides a high frequency high contrast area which appears to the image processing system as an undesirable area and which is eliminated thereby allowing an uninfluenced treatment of each of the pixels in an image including the pixels at the edges of an image. Any neighborhood influence resulting from border pixels near the edge of the image is eliminated because these border pixels appear as noise which is eliminated. The appearance of noise is due to the high frequency alternation of contrasting areas which are processed as noise and thereby eliminated.

Abstract: A light integrator in a first aspect, comprises:an elongated tapered solid core having first and second ends and an elongated surface therebetween, down which a decreasing total proportion of light can propagate by total internal reflection at the elongated surface;a layer of reflective material positioned adjacent at least a portion of the elongated surface, which reflective layer is of a first material having sufficient porosity, with pores which are vacant or contain a second material having an index of refraction lower than that of the core, such that the layer reduces total internal reflection in the core less than it would be reduced using a non-porous layer of the same dimensions of only the first material; andfirst and second light ports defined by regions of the core not covered by the reflective material, positioned such that light can pass through the first port, propagate down the core by total internal reflection at the elongated surface, while an increasing total proportion passes through the el