Abstract: The finding that phosphatidylserine (PtdSer) exposure on the outer leaflet of virally transduced cells triggers their engulfment by resident immune cells is described. It is demonstrated that inhibition of phospholipid scramblase 1 (PLSCR1) activity prevents PtdSer externalization and enables prolonged protection of vector-transduced cells from phagocytosis. Methods of inhibiting a virus vector-induced inflammatory response in tissue, methods of prolonging virus vector encoded transgene expression, and methods of modulating an inflammatory response in tissue of a subject, by administering an inhibitor of PLSCR1 are described.

Abstract: The finding that phosphatidylserine (PtdSer) exposure on the outer leaflet of virally transduced cells triggers their engulfment by resident immune cells is described. It is demonstrated that inhibition of phospholipid scramblase 1 (PLSCR1) activity prevents PtdSer externalization and enables prolonged protection of vector-transduced cells from phagocytosis. Methods of inhibiting a virus vector-induced inflammatory response in tissue, methods of prolonging virus vector encoded transgene expression, and methods of modulating an inflammatory response in tissue of a subject, by administering an inhibitor of PLSCR1 are described.

Abstract: Methods for handling raw oil are disclosed herein. Systems for handling raw oil are disclosed herein. Housing module structures related thereto are disclosed herein.

Abstract: A brake pad measuring device is designed to be small enough to fit through various suspension components or many vehicles' wheel aperture and still maintain the ability to move in three-dimensions. The device is compact enough so that it may take an accurate reading of the thickness of a brake pad while being between the caliper housing and the brake pad backing plate of a vehicle. The device also comprises a spring so that once it is correctly placed, it may be manipulated in order to automatically get a reading of the thickness of a brake pad to the closest millimeter or 32nd of an inch by releasing the spring to cause a measurement to be automatically taken. Using this device, any user can get quick, reliable measurements for all four sets of brake pads in a matter of minutes and all without having to remove a single wheel from the vehicle.