Patents by Inventor Charles Samuel Umbaugh

Charles Samuel Umbaugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11022604
    Abstract: An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 1, 2021
    Assignee: Purdue Research Foundation
    Inventors: Marxa L. Figueiredo, Charles Samuel Umbaugh, Herman O. Sintim, Adriana Diaz-Quinones
  • Publication number: 20200064334
    Abstract: An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
    Type: Application
    Filed: August 29, 2019
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Marxa L. Figueiredo, Charles Samuel Umbaugh, Herman O. Sintim, Adriana Diaz-Quinones
  • Patent number: 10438688
    Abstract: An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: October 8, 2019
    Assignee: Purdue Research Foundation
    Inventors: Marxa L. Figueiredo, Charles Samuel Umbaugh, Herman O. Sintim, Adriana Diaz-Quinones
  • Publication number: 20190065669
    Abstract: An in silico screening method generated compounds that are against laminin receptor 37 LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
    Type: Application
    Filed: August 27, 2018
    Publication date: February 28, 2019
    Applicant: Purdue Research Foundation
    Inventors: Marxa L. Figueiredo, Charles Samuel Umbaugh, Herman O. Sintim, Adriana Diaz-Quinones