Abstract: Devices and methods for non-invasive capillary blood pressure measurement are provided. An device can comprise a front end in contact with the body to compress and decompress the capillaries in the tissue, a pressure control module for regulating the contact pressure between the front end and the tissue, a pressure transducer coupled to the front end for measuring the contact pressure, a capillary sensing module for detecting the capillaries pulsations under the contact pressure modulation, and an algorithm for determining the capillaries pressures from the traces of capillary pulsation signals and the contact pressure signal. The methods include an oscillometric method for intermittent arterial and capillary blood pressure measurement and a volume-clamp method for continuous capillary blood pressure measurement.

Abstract: Devices and methods for non-invasive capillary blood pressure measurement are provided. An device can comprise a front end in contact with the body to compress and decompress the capillaries in the tissue, a pressure control module for regulating the contact pressure between the front end and the tissue, a pressure transducer coupled to the front end for measuring the contact pressure, a capillary sensing module for detecting the capillaries pulsations under the contact pressure modulation, and an algorithm for determining the capillaries pressures from the traces of capillary pulsation signals and the contact pressure signal. The methods include an oscillometric method for intermittent arterial and capillary blood pressure measurement and a volume-clamp method for continuous capillary blood pressure measurement.

Abstract: Described is a switched capacitor circuit for performing an analog circuit function. Unlike conventional switched capacitor circuits employing operational amplifiers, the switched capacitor circuit uses a comparator and does not require direct feedback between the input and output of the comparator. The switched capacitor circuit includes a first and a second switched capacitance network, a comparator and a current source. The first switched capacitance network has an input terminal to receive a circuit input voltage during a first phase. The comparator has an input terminal in communication with the first switched capacitance network and an output terminal in communication with the second switched capacitance network through a switched terminal. The current source communicates with the switched capacitance networks and supplies a current to charge the networks during a second phase. The circuit can be used, for example, to provide high gain amplification in integrated circuits.