Abstract: The present disclosure relates to ready-to-use liquid aqueous bortezomib compositions bortezomib and pharmaceutical excipients. Other aspects include methods of preparing such ready-to-use liquid aqueous bortezomib compositions, and methods of using such ready-to-use liquid bortezomib compositions in therapeutic applications.

Abstract: A method of producing graphene or other two-dimensional material such as graphene including heating the substrate held within a reaction chamber to a temperature that is within a decomposition range of a precursor, and that allows two-dimensional crystalline material formation from a species released from the decomposed precursor; establishing a steep temperature gradient (preferably >1000° C. per meter) that extends away from the substrate surface towards an inlet for the precursor; and introducing precursor through the relatively cool inlet and across the temperature gradient towards the substrate surface. The steep temperature gradient ensures that the precursor remains substantially cool until it is proximate the substrate surface thus minimizing decomposition or other reaction of the precursor before it is proximate the substrate surface. The separation between the precursor inlet and the substrate is less than 100 mm.

Abstract: The disclosed haptic vibrotactile actuators on inflatable bladders may include an inflatable bladder and a flexible haptic vibrotactile actuator positioned on or in the inflatable bladder such that inflation and deflation of the inflatable bladder alters a vibrotactile sensation induced by the flexible haptic vibrotactile actuator in response to activation of the flexible haptic vibrotactile actuator. Various other related methods and systems are also disclosed.

Abstract: A method of producing graphene or other two-dimensional material such as graphene including heating the substrate held within a reaction chamber to a temperature that is within a decomposition range of a precursor, and that allows two-dimensional crystalline material formation from a species released from the decomposed precursor; establishing a steep temperature gradient (preferably >1000° C. per meter) that extends away from the substrate surface towards an inlet for the precursor; and introducing precursor through the relatively cool inlet and across the temperature gradient towards the substrate surface. The steep temperature gradient ensures that the precursor remains substantially cool until it is proximate the substrate surface thus minimizing decomposition or other reaction of the precursor before it is proximate the substrate surface. The separation between the precursor inlet and the substrate is less than 100 mm.

Abstract: A method is provided for treating back pain whereby a person sits comfortably in a seated position in a chair and fastens their upper body above the waist to the seat back and fastens their lower body at just above the buttocks and then by means of leaning back allows the seat back to pull the person's upper body away from their lower body providing spinal traction.

Abstract: Systems and methods for reducing the deleterious effects of specular reflections (e.g., glint) on active illumination systems are disclosed. An example system includes an illuminator or light source configured to illuminate a scene with electromagnetic radiation having a defined polarization orientation. The system also includes a receiver for receiving portions of the electromagnetic radiation reflected or scatter from the scene. Included in the receiver is a polarizer having a polarization axis crossed with the polarization orientation of the emitted electromagnetic radiation. By crossing the polarizer with the polarization of the emitted electromagnetic radiation, the polarizer may filter out glint or specular reflections in the electromagnetic radiation returned from the scene.

Abstract: A method of producing graphene or other two-dimensional material such as graphene including heating the substrate held within a reaction chamber to a temperature that is within a decomposition range of a precursor, and that allows two-dimensional crystalline material formation from a species released from the decomposed precursor; establishing a steep temperature gradient (preferably >1000° C. per meter) that extends away from the substrate surface towards an inlet for the precursor; and introducing precursor through the relatively cool inlet and across the temperature gradient towards the substrate surface. The steep temperature gradient ensures that the precursor remains substantially cool until it is proximate the substrate surface thus minimizing decomposition or other reaction of the precursor before it is proximate the substrate surface. The separation between the precursor inlet and the substrate is less than 100 mm.

Abstract: A method of producing graphene or other two-dimensional material such as graphene including heating the substrate held within a reaction chamber to a temperature that is within a decomposition range of a precursor, and that allows two-dimensional crystalline material formation from a species released from the decomposed precursor; establishing a steep temperature gradient (preferably >1000° C. per meter) that extends away from the substrate surface towards an inlet for the precursor; and introducing precursor through the relatively cool inlet and across the temperature gradient towards the substrate surface. The steep temperature gradient ensures that the precursor remains substantially cool until it is proximate the substrate surface thus minimizing decomposition or other reaction of the precursor before it is proximate the substrate surface. The separation between the precursor inlet and the substrate is less than 100 mm.

Abstract: Imaging systems and methods are disclosed that use multiple illumination pulses to irradiate a scene of interest. An example system includes optics to receive a sequence of returned light pulse portions scattered or reflected from the scene. A modulator is configured to modulate the intensity of the returned light pulse portions to form a sequence of modulated light pulse portions. A means of selectively exposing a sensor during a sequence of exposure periods is also included, so that each modulated light pulse portion is received by the sensor during one of the exposure periods, respectively. The sensor is configured to generate a sequence of sensor signals as a result of receiving the modulated light pulse portions and to accumulate the sensor signals to form a sensor output signal. A processor may read the sensor output signal and process the image based on that signal.

Abstract: A haptic glove comprises a glove body including a glove digit corresponding to a phalange of a user hand with the glove digit having a bend location that is located along the glove digit. A haptic apparatus is coupled to the glove body at the bend location with the haptic apparatus comprising a plurality of sheets that are flexible and inextensible and a pressure actuator coupled to one or more of the plurality of sheets. The plurality of sheets are stacked and configured to translate relative to each other along the centerline with bending of the glove digit. The pressure actuator is configured to adjust an applied pressure to the plurality of sheets to adjust friction between the sheets. The adjustment of friction is proportional to a bending resistance of the glove digit.

Abstract: An apparatus for creating haptic stimulations is provided. The apparatus includes one or more pods coupled to a garment, each pod including: (i) an internal structure, and (ii) an airtight bladder surrounding the internal structure, where the bladder is pneumatically coupled to a pneumatic device that is configured to control a pressurized state of the bladder. Each pod is configured to: (i) have a first degree of flexibility when the bladder of the pod is in a first pressurized state; and (ii) have a second degree of flexibility, less than the first degree of flexibility, when the bladder of the pod is in a second pressurized state different from the first pressurized state. Each pod provides a haptic stimulation to a wearer of the garment when the corresponding bladder is in the second pressurized state.

Abstract: A spiralizer attachment (70) for a kitchen appliance includes a body and a rotatable plate (60) associated with the body. The blade plate includes a slot (86) and at least one blade (88). Rotation of the blade plate relative to a food item forms at least one continuous slice of the food item.

Abstract: The disclosed haptic vibrotactile actuators on inflatable bladders may include an inflatable bladder and a flexible haptic vibrotactile actuator positioned on or in the inflatable bladder such that inflation and deflation of the inflatable bladder alters a vibrotactile sensation induced by the flexible haptic vibrotactile actuator in response to activation of the flexible haptic vibrotactile actuator. Various other related methods and systems are also disclosed.

Abstract: The disclosed haptic vibrotactile actuator may include a textile comprising a first major surface and a second, opposite major surface, an electrode coupled to the first major surface of the textile across at least a majority of a surface area of a first surface of the electrode, and a flexible electroactive material electrically coupled to a second, opposite surface of the electrode. Various other related methods and systems are also disclosed.

Abstract: Methods, systems and apparatus that provide for perceptual, cognitive, and motor behaviors in an integrated system implemented using neural architectures. Components of the system communicate using artificial neurons that implement neural networks. The connections between these networks form representations—referred to as semantic pointers—which model the various firing patterns of biological neural network connections. Semantic pointers can be thought of as elements of a neural vector space, and can implement a form of abstraction level filtering or compression, in which high-dimensional structures can be abstracted one or more times thereby reducing the number of dimensions needed to represent a particular structure.

Abstract: A food processing system includes a container for receiving a food item processed by said food processing system. A configuration of said processing performed by said food processing system is determined by a position of the food item as it enters said container.

Abstract: A wellhead system includes a sequence valve in fluid communication with a wellhead device having a first hydraulic actuation device and a second hydraulic actuation device. The sequence valve includes a valve element configured to direct flow to the first hydraulic actuation device in a closed position and to direct flow to the second hydraulic actuation device in an open position. The sequence valve can actuate the second hydraulic actuation device after fully actuating the first hydraulic actuation device. Because the sequence valve can control the order of actuation of the actuation devices, the sequence valve can simplify the operation of the wellhead device and prevent incomplete or improper actuation of the wellhead device. The sequence valve can be utilized in remote and high pressure applications. Because of this, the sequence valve can provide reliable operation in various configurations.

Abstract: Methods for obtaining natural colorants from plant material (e.g., tobacco material) and for using such natural colorants to dye various substrates are provided. Natural colorants are obtained using particular enzymes and particular conditions (e.g., time, temperature, and pH profiles). Such colorants can be used to dye substrates, for example, using conventional dyeing techniques or using unique in situ methods.

Abstract: A food processing system includes a food processor wherein an initial operation of said food processor is configured to cut a food item in a first, generally vertical direction and a later operation of said food processor is configured to cut said food item in a second direction. The second direction is distinct from the vertical direction.

Abstract: Methods for obtaining natural colorants from plant material (e.g., tobacco material) and for using such natural colorants to dye various substrates are provided. Natural colorants are obtained using particular enzymes and particular conditions (e.g., time, temperature, and pH profiles). Such colorants can be used to dye substrates, for example, using conventional dyeing techniques or using unique in situ methods.