Patents by Inventor Charles Williams Flexner

Charles Williams Flexner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELF-ASSEMBLING ANTIVIRAL PRODRUGS
    Publication number: 20230147365
    Abstract: Disclosed are therapeutic self-assembling molecules including a peptide sequence conjugated to one or more antiviral therapeutics to form a peptide-based antiviral prodrug capable of self-assembly into supramolecular structures with varying morphology in aqueous solutions, which can be injected subcutaneously or intramuscularly for the long-acting treatment of chronic viral infections.
    Type: Application
    Filed: November 7, 2022
    Publication date: May 11, 2023
    Inventors: Honggang Cui, Charles Williams Flexner, Maya Monroe, Han Wang
  • Prodrug compositions
    Patent number: 11498933
    Abstract: The present invention provides a composition comprising nanoparticles of prodrugs of certain pharmaceutically active agents, wherein the nanoparticles of prodrugs are dispersed within a carrier material. The present invention further provides processes for the making of the same.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: November 15, 2022
    Assignees: The John Hopkins University
    Inventors: Steven Paul Rannard, Andrew Owen, Paul Curley, James Hobson, Marco Siccardi, Caren L. Freel Meyers, Amer Al-Khouja, David J. Meyers, Charles Williams Flexner
  • METHOD FOR PRODUCING A LIQUID COMPOSITION
    Publication number: 20200114012
    Abstract: A first aspect of the present invention provides a method of producing a liquid composition comprising stabilised particles of active species in oil by precipitating a solution of the active species in a non-solvent in the presence of one or more stabilisers, mixing the precipitate suspension with an oil and then removing the solvents. Further aspects of the present invention relate to liquid compositions produced by said method and methods of use of such liquid compositions.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 16, 2020
    Inventors: Steven Paul Rannard, Andrew Owen, Paul Curley, James Hobson, Marco Siccardi, Caren L. Freel Meyers, Amer Al-Khouja, David J. Meyers, Charles Williams Flexner
  • PRODRUG COMPOSITIONS
    Publication number: 20200040015
    Abstract: The present invention provides a composition comprising nanoparticles of prodrugs of certain pharmaceutically active agents, wherein the nanoparticles of prodrugs are dispersed within a carrier material. The present invention further provides processes for the making of the same.
    Type: Application
    Filed: March 29, 2018
    Publication date: February 6, 2020
    Inventors: Steven Paul Rannard, Andrew Owen, Paul Curley, James Hobson, Marco Siccardi, Caren L. Freel Meyers, Amer Al-Khouja, David J. Meyers, Charles Williams Flexner