Patents by Inventor Chen-Yaw Chiu

Chen-Yaw Chiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO TREAT ASTHMA AND AIRWAY ALLERGY USING CYCLO TYROSINE-VALINE AND RELATED COMPOUNDS
    Publication number: 20190183960
    Abstract: The present invention provides a method to treat asthma and airway allergy by administering the dipeptide cyclo tyrosine-valine or a related cyclodipeptide compound to a subject in need thereof. Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperresponsiveness, accumulation of immune cells in bronchoalveolar fluid, and allergen-specific antibody production in an animal or human subject. The compound can therefore be used to treat asthma and airway allergy.
    Type: Application
    Filed: February 27, 2018
    Publication date: June 20, 2019
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, Chen-Yaw Chiu, Chuan-Sheng Lin, Luis Dominick B. Antig, Pei-Wen Hsieh, Yu-Li Chen, Chih-Jung Chang, Tsung-Ru Wu, David Marcelo Ojcius, Chia-Chen Lu, Hsin-Chih Lai, John D. Young
  • Method to treat fatty liver disease using
    Patent number: 10111915
    Abstract: The present invention describes a method to reduce blood aspartate transaminase level, liver weight, hepatic lipid accumulation and hepatocyte hypertrophy by administering the probiotic bacterium Parabacteroides goldsteinii to a subject showing signs of fatty liver disease. This probiotic bacterium can therefore be used to treat fatty liver disease.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: October 30, 2018
    Assignee: CHANG GUNG BIOTECHNOLOGY CORP.
    Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • Method to reduce insulin resistance and improve glucose tolerance using
    Patent number: 10086019
    Abstract: The present invention provides a method to reduce insulin resistance and improve glucose tolerance by administering the probiotic bacterium Parabacteroides goldsteinii. This probiotic bacterium can therefore be used to treat insulin resistance, metabolic syndrome, and type 2 diabetes.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: October 2, 2018
    Assignee: CHANG GUNG BIOTECHNOLOGY CORP.
    Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • Method to reduce body weight, fat accumulation and adipocyte size using
    Patent number: 9956255
    Abstract: The present invention describes a method to reduce body weight, fat accumulation and adipocyte size by administering the probiotic bacterium Parabacteroides goldsteinii. This probiotic bacterium can therefore be used to treat obesity in animals and humans.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: May 1, 2018
    Assignee: CHANG GUNG BIOTECHNOLOGY CORP.
    Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • Method to prepare polysaccharides possessing insulin-sensitizing properties and applications thereof
    Patent number: 9828442
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce hyperglycemia and insulin resistance, and can therefore be used to prevent and treat type 2 diabetes and related conditions.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: November 28, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • Method to prepare polysaccharides possessing protective activities on fatty liver disease
    Patent number: 9782447
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce liver size, weight and the number and size of liver lipid vacuoles, as well as serum triglycerides and serum aspartate aminotransferase levels in humans and animals. The prepared polysaccharides can therefore be used to prevent and treat fatty liver disease.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: October 10, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • Method to prepare hirsutella sinensis polysaccharides possessing anti-obesity properties and uses thereof
    Patent number: 9782431
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: October 10, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • Method to prepare polysaccharides possessing protective activities on fatty liver disease
    Patent number: 9763990
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce liver weight and liver lipid content in humans and animals. The prepared polysaccharides can therefore be used to prevent and treat fatty liver disease.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: September 19, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • Method to prepare ganoderma lucidum polysaccharides possessing insulin-sensitizing properties and applications thereof
    Patent number: 9757409
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce hyperglycemia and improve insulin sensitivity in humans and animals, and can therefore be used to prevent and treat type 2 diabetes.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: September 12, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • Method to prepare polysaccharides possessing anti-obesity properties and uses thereof
    Patent number: 9758595
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: September 12, 2017
    Assignee: Chang Gung Biotechnology Corp.
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
  • METHOD TO PREPARE GANODERMA LUCIDUM POLYSACCHARIDES POSSESSING PROTECTIVE ACTIVITIES ON FATTY LIVER DISEASE
    Publication number: 20170028003
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce liver weight and liver lipid content in humans and animals. The prepared polysaccharides can therefore be used to prevent and treat fatty liver disease.
    Type: Application
    Filed: September 23, 2015
    Publication date: February 2, 2017
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING INSULIN-SENSITIZING PROPERTIES AND APPLICATIONS THEREOF
    Publication number: 20160361341
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce hyperglycemia and insulin resistance, and can therefore be used to prevent and treat type 2 diabetes and related conditions.
    Type: Application
    Filed: September 15, 2015
    Publication date: December 15, 2016
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING ANTI-OBESITY PROPERTIES AND USES THEREOF
    Publication number: 20160361348
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.
    Type: Application
    Filed: September 16, 2015
    Publication date: December 15, 2016
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING PROTECTIVE ACTIVITIES ON FATTY LIVER DISEASE
    Publication number: 20160361370
    Abstract: The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce liver size, weight and the number and size of liver lipid vacuoles, as well as serum triglycerides and serum aspartate aminotransferase levels in humans and animals. The prepared polysaccharides can therefore be used to prevent and treat fatty liver disease.
    Type: Application
    Filed: September 16, 2015
    Publication date: December 15, 2016
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Chien-Sheng Lee, Wei-Chang Wang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • METHOD TO PREPARE GANODERMA LUCIDUM POLYSACCHARIDES POSSESSING INSULIN-SENSITIZING PROPERTIES AND APPLICATIONS THEREOF
    Publication number: 20160354405
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce hyperglycemia and improve insulin sensitivity in humans and animals, and can therefore be used to prevent and treat type 2 diabetes.
    Type: Application
    Filed: September 15, 2015
    Publication date: December 8, 2016
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young
  • METHOD TO PREPARE GANODERMA LUCIDUM POLYSACCHARIDES POSSESSING ANTI-OBESITY PROPERTIES AND USES THEREOF
    Publication number: 20160347867
    Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.
    Type: Application
    Filed: September 15, 2015
    Publication date: December 1, 2016
    Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, Ding-E Young